Chromogenic detection of yam mosaic virus by closed-tube reverse transcription loop-mediated isothermal amplification (CT-RT-LAMP)

A closed-tube reverse transcription loop-mediated isothermal amplification (CT-RT-LAMP) assay was developed for the detection of yam mosaic virus (YMV, genus Potyvirus) infecting yam (Dioscorea spp.). The assay uses a set of six oligonucleotide primers targeting the YMV coat protein region, and the...

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Main Authors: Nkere, C.K., Oyekanmi, J.O., Silva, G., Bömer, M., Atiri, G.I., Onyeka, J., Maroya, N.G., Seal, S.E., Kumar, P. Lava
Format: Journal Article
Language:Inglés
Published: Springer 2018
Subjects:
Online Access:https://hdl.handle.net/10568/108663
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author Nkere, C.K.
Oyekanmi, J.O.
Silva, G.
Bömer, M.
Atiri, G.I.
Onyeka, J.
Maroya, N.G.
Seal, S.E.
Kumar, P. Lava
author_browse Atiri, G.I.
Bömer, M.
Kumar, P. Lava
Maroya, N.G.
Nkere, C.K.
Onyeka, J.
Oyekanmi, J.O.
Seal, S.E.
Silva, G.
author_facet Nkere, C.K.
Oyekanmi, J.O.
Silva, G.
Bömer, M.
Atiri, G.I.
Onyeka, J.
Maroya, N.G.
Seal, S.E.
Kumar, P. Lava
author_sort Nkere, C.K.
collection Repository of Agricultural Research Outputs (CGSpace)
description A closed-tube reverse transcription loop-mediated isothermal amplification (CT-RT-LAMP) assay was developed for the detection of yam mosaic virus (YMV, genus Potyvirus) infecting yam (Dioscorea spp.). The assay uses a set of six oligonucleotide primers targeting the YMV coat protein region, and the amplification products in YMV-positive samples are visualized by chromogenic detection with SYBR Green I dye. The CT-RT-LAMP assay detected YMV in leaf and tuber tissues of infected plants. The assay is 100 times more sensitive in detecting YMV than standard RT-PCR, while maintaining the same specificity.
format Journal Article
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institution CGIAR Consortium
language Inglés
publishDate 2018
publishDateRange 2018
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spelling CGSpace1086632025-11-11T10:09:05Z Chromogenic detection of yam mosaic virus by closed-tube reverse transcription loop-mediated isothermal amplification (CT-RT-LAMP) Nkere, C.K. Oyekanmi, J.O. Silva, G. Bömer, M. Atiri, G.I. Onyeka, J. Maroya, N.G. Seal, S.E. Kumar, P. Lava yams viruses plant viruses plant condition plant diseases production virology A closed-tube reverse transcription loop-mediated isothermal amplification (CT-RT-LAMP) assay was developed for the detection of yam mosaic virus (YMV, genus Potyvirus) infecting yam (Dioscorea spp.). The assay uses a set of six oligonucleotide primers targeting the YMV coat protein region, and the amplification products in YMV-positive samples are visualized by chromogenic detection with SYBR Green I dye. The CT-RT-LAMP assay detected YMV in leaf and tuber tissues of infected plants. The assay is 100 times more sensitive in detecting YMV than standard RT-PCR, while maintaining the same specificity. 2018-04 2020-07-03T08:48:56Z 2020-07-03T08:48:56Z Journal Article https://hdl.handle.net/10568/108663 en Open Access application/pdf Springer Nkere, C.K., Oyekanmi, J.O., Silva, G., Bömer, M., Atiri, G.I., Onyeka, J., ... & Kumar, P.L. (2018). Chromogenic detection of yam mosaic virus by closed-tube reverse transcription loop-mediated isothermal amplification (CT-RT-LAMP). Archives of Virology, 163(4), 1057-1061.
spellingShingle yams
viruses
plant viruses
plant condition
plant diseases
production
virology
Nkere, C.K.
Oyekanmi, J.O.
Silva, G.
Bömer, M.
Atiri, G.I.
Onyeka, J.
Maroya, N.G.
Seal, S.E.
Kumar, P. Lava
Chromogenic detection of yam mosaic virus by closed-tube reverse transcription loop-mediated isothermal amplification (CT-RT-LAMP)
title Chromogenic detection of yam mosaic virus by closed-tube reverse transcription loop-mediated isothermal amplification (CT-RT-LAMP)
title_full Chromogenic detection of yam mosaic virus by closed-tube reverse transcription loop-mediated isothermal amplification (CT-RT-LAMP)
title_fullStr Chromogenic detection of yam mosaic virus by closed-tube reverse transcription loop-mediated isothermal amplification (CT-RT-LAMP)
title_full_unstemmed Chromogenic detection of yam mosaic virus by closed-tube reverse transcription loop-mediated isothermal amplification (CT-RT-LAMP)
title_short Chromogenic detection of yam mosaic virus by closed-tube reverse transcription loop-mediated isothermal amplification (CT-RT-LAMP)
title_sort chromogenic detection of yam mosaic virus by closed tube reverse transcription loop mediated isothermal amplification ct rt lamp
topic yams
viruses
plant viruses
plant condition
plant diseases
production
virology
url https://hdl.handle.net/10568/108663
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