Isoflavone sources and bioavailability
Over the last couple of decades non-nutritional bioactive compounds from plants and their biological effects have received attention. Phytoestrogens, also called “plant estrogens”, with their similar structure to estradiol, act with estrogenic effects when imbibed. The compounds that have received c...
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| Formato: | First cycle, G2E |
| Lenguaje: | Inglés Inglés |
| Publicado: |
2017
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| Acceso en línea: | https://stud.epsilon.slu.se/9922/ |
| _version_ | 1855571608163319808 |
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| author | Gatchell, Sara |
| author_browse | Gatchell, Sara |
| author_facet | Gatchell, Sara |
| author_sort | Gatchell, Sara |
| collection | Epsilon Archive for Student Projects |
| description | Over the last couple of decades non-nutritional bioactive compounds from plants and their biological effects have received attention. Phytoestrogens, also called “plant estrogens”, with their similar structure to estradiol, act with estrogenic effects when imbibed. The compounds that have received considerable interest are, among others, the Isoflavones, of which significant quantities can be found in most members of the family Leguminosae (Fabaceae). Soy, a member of the leguminosae, is the main nutritional source to these phytoestrogenic isoflavones. Isoflavones are commonly consumed in East Asia but less so in the western world. It is highly suggested that the health effects of isoflavones are dependent on the consumer’s ability to digest the substances. This article reviews these estrogen active, polyphenolic compounds present in soy- and bovine milk for the comparison of isoflavone content, bioavailability, and isoflavone related health effects. The mechanisms are also reviewed. This is done for understanding the eventual importance of these phytoestrogens as a part of the diet, and why variation of sources may be of interest for parts of the population. Preliminary study shows phytoestrogen having a largely positive health effect. But only approximately 30-50% of the population are so called “equol-producers” and for the other half soy may not be an optimal isoflavone source and instead bovine milk may serve as an alternative and/or additional dietary source, as isoflavone metabolites have been traced in cow’s milk. |
| format | First cycle, G2E |
| id | RepoSLU9922 |
| institution | Swedish University of Agricultural Sciences |
| language | Inglés Inglés |
| publishDate | 2017 |
| publishDateSort | 2017 |
| record_format | eprints |
| spelling | RepoSLU99222017-01-24T12:34:32Z https://stud.epsilon.slu.se/9922/ Isoflavone sources and bioavailability Gatchell, Sara Physiology of human nutrition Over the last couple of decades non-nutritional bioactive compounds from plants and their biological effects have received attention. Phytoestrogens, also called “plant estrogens”, with their similar structure to estradiol, act with estrogenic effects when imbibed. The compounds that have received considerable interest are, among others, the Isoflavones, of which significant quantities can be found in most members of the family Leguminosae (Fabaceae). Soy, a member of the leguminosae, is the main nutritional source to these phytoestrogenic isoflavones. Isoflavones are commonly consumed in East Asia but less so in the western world. It is highly suggested that the health effects of isoflavones are dependent on the consumer’s ability to digest the substances. This article reviews these estrogen active, polyphenolic compounds present in soy- and bovine milk for the comparison of isoflavone content, bioavailability, and isoflavone related health effects. The mechanisms are also reviewed. This is done for understanding the eventual importance of these phytoestrogens as a part of the diet, and why variation of sources may be of interest for parts of the population. Preliminary study shows phytoestrogen having a largely positive health effect. But only approximately 30-50% of the population are so called “equol-producers” and for the other half soy may not be an optimal isoflavone source and instead bovine milk may serve as an alternative and/or additional dietary source, as isoflavone metabolites have been traced in cow’s milk. De senaste decennierna har det funnits ett ökat intresse för växters bioaktiva ämnen och biologiska effekt. Fytoöstrogen, eller ”växtöstrogen”, med liknande struktur som östradiol, verkar med likhet på kroppen som dess eget östrogen vid konsumtion. De kemiska föreningarna som det har intresserats mest för har bland annat varit isoflavonerna, vilka höga koncentrationer går att finna i växter från familjen Fabaceae. Soja är medlem i familjen och fungerar också som, för människan, den största nutritionella källan. Isoflavoner konsumeras i högre grad i Ostasien, jämfört med västvärlden. Det har föreslagits att isoflavonernas hälsoeffekter är i stark relation till konsumentens förmåga att bryta ner dessa ämnen till deras metaboliter, bland annat equol som har stark likhet med östradiol. Denna artikel sammanfattar dessa östrogenaktiva polyfenolers förekomst, hälsoeffekt och biotillgänglighet i soja- och komjölk. Mekanismer granskas också. Detta är gjort för att öka förståelsen kring varför det kan vara nödvändigt med fytoöstrogener i dieten och varför det eventuellt skulle vara viktigt med varierande källor till dessa. Vid en preliminär granskning verkar isoflavoners hälsoeffekter överlag vara positiva. Bara ca 30-50% av befolkningen kan producera equol från de isoflavoner som finns i soja, för den andra delen kanske soja trots allt inte är den optimala källan till isoflavoner utan istället kan kanske komjölk vara en alternativ källa. Detta då man har kunnat hitta nivåer av dessa isoflavonmetaboliter i mjölk. 2017-01-19 First cycle, G2E NonPeerReviewed application/pdf en https://stud.epsilon.slu.se/9922/1/gatchell_s_170124.pdf Gatchell, Sara, 2016. Isoflavone sources and bioavailability : biological effects of phytoestrogens in the diet. First cycle, G2E. Uppsala: (NL, NJ) > Dept. of Food Science <https://stud.epsilon.slu.se/view/divisions/OID-550.html> urn:nbn:se:slu:epsilon-s-6178 eng |
| spellingShingle | Physiology of human nutrition Gatchell, Sara Isoflavone sources and bioavailability |
| title | Isoflavone sources and bioavailability |
| title_full | Isoflavone sources and bioavailability |
| title_fullStr | Isoflavone sources and bioavailability |
| title_full_unstemmed | Isoflavone sources and bioavailability |
| title_short | Isoflavone sources and bioavailability |
| title_sort | isoflavone sources and bioavailability |
| topic | Physiology of human nutrition |
| url | https://stud.epsilon.slu.se/9922/ https://stud.epsilon.slu.se/9922/ |