Analysis of inbreeding in the Swedish Gotland pony using pedigree information and microsatellite markers
In this study inbreeding in the Swedish indigenous breed Gotland pony has been investigated using traditional genealogical methods and microsatellite markers. Since the breed is classified as endangered-maintained, it is valuable to know the inbreeding status and population structure. Pedigree data...
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| Formato: | H2 |
| Lenguaje: | Inglés sueco |
| Publicado: |
SLU/Dept. of Animal Breeding and Genetics (until 231231)
2010
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| Materias: |
| _version_ | 1855571431211925504 |
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| author | Andersson, Linda |
| author_browse | Andersson, Linda |
| author_facet | Andersson, Linda |
| author_sort | Andersson, Linda |
| collection | Epsilon Archive for Student Projects |
| description | In this study inbreeding in the Swedish indigenous breed Gotland pony has been investigated using traditional genealogical methods and microsatellite markers. Since the breed is classified as endangered-maintained, it is valuable to know the inbreeding status and population structure. Pedigree data was very complete with PEC-values for some horses above 0.8 already during the first decades of the 1900’s. The average inbreeding coefficient was 0.11 for horses born 1996 to 2005. The average increase in inbreeding was 0.75 % per generation since 1985. The average generation interval was 10.4 years. The inbreeding effective population size was 67 individuals. The effective population size based on the variance in progeny group was 235 ponies. On average, each year 10 new stallions and 81 new mares were used in breeding every year. The majority of stallions used in breeding had between 1 and 20 registered offspring.
The DNA profiles from 344 horses were analysed. In total 16 markers were considered. FIS, a measure of inbreeding related to the subpopulation, was 0.014 when considering all 344 animals as a single population. The expected level of heterozygosity was 0.643 while the observed was 0.635. One marker, AHT5, was found not to be in Hardy-Weinberg equilibrium, indicating some kind of selection. |
| format | H2 |
| id | RepoSLU8923 |
| institution | Swedish University of Agricultural Sciences |
| language | Inglés swe |
| publishDate | 2010 |
| publishDateSort | 2010 |
| publisher | SLU/Dept. of Animal Breeding and Genetics (until 231231) |
| publisherStr | SLU/Dept. of Animal Breeding and Genetics (until 231231) |
| record_format | eprints |
| spelling | RepoSLU89232016-03-22T12:20:25Z Analysis of inbreeding in the Swedish Gotland pony using pedigree information and microsatellite markers Analys av inavel hos svenska gotlandsruss baserad på härstamningsinformation och molekylärgenetiska markörer Andersson, Linda Gotland pony inbreeding effective population size microsatellite markers pedigree information heterozygosity In this study inbreeding in the Swedish indigenous breed Gotland pony has been investigated using traditional genealogical methods and microsatellite markers. Since the breed is classified as endangered-maintained, it is valuable to know the inbreeding status and population structure. Pedigree data was very complete with PEC-values for some horses above 0.8 already during the first decades of the 1900’s. The average inbreeding coefficient was 0.11 for horses born 1996 to 2005. The average increase in inbreeding was 0.75 % per generation since 1985. The average generation interval was 10.4 years. The inbreeding effective population size was 67 individuals. The effective population size based on the variance in progeny group was 235 ponies. On average, each year 10 new stallions and 81 new mares were used in breeding every year. The majority of stallions used in breeding had between 1 and 20 registered offspring. The DNA profiles from 344 horses were analysed. In total 16 markers were considered. FIS, a measure of inbreeding related to the subpopulation, was 0.014 when considering all 344 animals as a single population. The expected level of heterozygosity was 0.643 while the observed was 0.635. One marker, AHT5, was found not to be in Hardy-Weinberg equilibrium, indicating some kind of selection. I detta arbete har inaveln inom den svenska ponnyrasen Gotlandsrusset undersökts både genom analys av härstamningsdata och via molekylärgenetiska metoder. Rasen är klassad som ”hotad-bevarad” och därför är rasens inavelsstatus viktig att veta. Härstamningsdata var förhållandevis komplett då PEC-värden över 0,8 förekom för en del hästar redan under de första årtiondena under 1900-talet. Medelinavelskoefficienten var 0,11 för hästar födda mellan 1996-2005. Den genomsnittliga ökningen av inavelsgraden var 0,75 % per generation för hästar födda efter 1985. Det genomsnittliga generationsintervallet var 10.4 år. Den inavelseffektiva populationsstorleken är 67 djur. Den effektiva populationsstorleken baserad på variationen i avkommegruppstorlek gav 235 djur. I genomsnitt sattes det in 10 nya hingstar och 81 ston i avel per år. Majoriteten av hingstar i avel har mellan 1 och 20 registrerade avkommor. Vid den molekylärgenetiska analysen har DNA-information från 344 russ använts och 16 mikrosatelliter har analyserats. FIS, ett mått på inavel relaterat till en subpopulation, är 0,014 för alla 344 djur. Den förväntade heterozygotigraden var 0,643, medan den observerade heterozygotigraden är 0,635. För alla 344 djur var en markör, AHT5, inte i Hardy-Weinberg jämvikt, vilket kan tyda på någon slags selektion. SLU/Dept. of Animal Breeding and Genetics (until 231231) 2010 H2 eng swe https://stud.epsilon.slu.se/8923/ |
| spellingShingle | Gotland pony inbreeding effective population size microsatellite markers pedigree information heterozygosity Andersson, Linda Analysis of inbreeding in the Swedish Gotland pony using pedigree information and microsatellite markers |
| title | Analysis of inbreeding in the Swedish Gotland pony using pedigree information and microsatellite markers |
| title_full | Analysis of inbreeding in the Swedish Gotland pony using pedigree information and microsatellite markers |
| title_fullStr | Analysis of inbreeding in the Swedish Gotland pony using pedigree information and microsatellite markers |
| title_full_unstemmed | Analysis of inbreeding in the Swedish Gotland pony using pedigree information and microsatellite markers |
| title_short | Analysis of inbreeding in the Swedish Gotland pony using pedigree information and microsatellite markers |
| title_sort | analysis of inbreeding in the swedish gotland pony using pedigree information and microsatellite markers |
| topic | Gotland pony inbreeding effective population size microsatellite markers pedigree information heterozygosity |