Hypertrophic osteoarthropathy in wildlife
In this essay suggested pathogenesis of secondary hypertrophic osteoarthropathy (HOA) is reviewed. HOA, characterized by; periostitis, periosteal proliferation of tubular bones and arthritis can develop due to many different underlying diseases. The syndrome is most commonly seen with intra-thoracic...
| Autor principal: | |
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| Formato: | First cycle, G2E |
| Lenguaje: | sueco Inglés |
| Publicado: |
2015
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| Acceso en línea: | https://stud.epsilon.slu.se/7926/ |
| _version_ | 1855571265491828736 |
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| author | Thorsson, Elina |
| author_browse | Thorsson, Elina |
| author_facet | Thorsson, Elina |
| author_sort | Thorsson, Elina |
| collection | Epsilon Archive for Student Projects |
| description | In this essay suggested pathogenesis of secondary hypertrophic osteoarthropathy (HOA) is reviewed. HOA, characterized by; periostitis, periosteal proliferation of tubular bones and arthritis can develop due to many different underlying diseases. The syndrome is most commonly seen with intra-thoracic malignancy or chronic pulmonary infections. HOA has previously mainly been described in humans and various domesticated species. More recently, through wildlife disease monitoring, cases have also been found among wild animals. This essay also aims to summarize the spectra of wild species in which the syndrome has been reported. Finding a coherent pathogenesis has proven to be difficult. Many theories overlap and are not yet fully investigated. Factors of importance include hypoxia, VEGF, PDGF and prostaglandins, but HOA is often suggested to be idiopathic. It is now obvious that secondary HOA affects a wide range of species. Even though the manifestation of the syndrome differs slightly between humans and animals it is similar in many aspects. Considering the similarities it can be presumed that the same pathogenesis applies for humans, domestic animals and wild animals. |
| format | First cycle, G2E |
| id | RepoSLU7926 |
| institution | Swedish University of Agricultural Sciences |
| language | Swedish Inglés |
| publishDate | 2015 |
| publishDateSort | 2015 |
| record_format | eprints |
| spelling | RepoSLU79262015-05-12T10:35:28Z https://stud.epsilon.slu.se/7926/ Hypertrophic osteoarthropathy in wildlife Thorsson, Elina Animal diseases In this essay suggested pathogenesis of secondary hypertrophic osteoarthropathy (HOA) is reviewed. HOA, characterized by; periostitis, periosteal proliferation of tubular bones and arthritis can develop due to many different underlying diseases. The syndrome is most commonly seen with intra-thoracic malignancy or chronic pulmonary infections. HOA has previously mainly been described in humans and various domesticated species. More recently, through wildlife disease monitoring, cases have also been found among wild animals. This essay also aims to summarize the spectra of wild species in which the syndrome has been reported. Finding a coherent pathogenesis has proven to be difficult. Many theories overlap and are not yet fully investigated. Factors of importance include hypoxia, VEGF, PDGF and prostaglandins, but HOA is often suggested to be idiopathic. It is now obvious that secondary HOA affects a wide range of species. Even though the manifestation of the syndrome differs slightly between humans and animals it is similar in many aspects. Considering the similarities it can be presumed that the same pathogenesis applies for humans, domestic animals and wild animals. I denna uppsats beskrivs olika teorier avseende patogenesen till sekundär hypertrofisk osteoartropati (HOA). Den patologiska bilden av HOA innefattar periostit med typisk periostal proliferation av rörben samt artrit. Syndromet anses kunna orsakas av flera olika sjukdomar som underliggande orsak, men ses oftast i samband med intratorakal malignitet eller kronisk lunginflammation. Äldre literatur har visat att sekundär HOA drabbar människa och ett flertal domesticerade djurarter. På senare tid har fall också rapporterats hos flera olika vilda djurarter. Denna uppsats syftar även till att sammanställa det spektrum av vilda djurarter där sekundär HOA finns rapporterat. Att finna en sammanhängande patogenes har visat sig vara svårt då teorierna är många, men sparsamt utredda. Faktorer som anses kunna vara inblandade i processen är hypoxi, tillväxtfaktorer som VEGF, PDGF samt prostaglandiner. Men ofta anges orsaken vara idiopatisk. Litteraturgenomgången har klart visat att sekundär HOA drabbar ett stort antal djurarter. Hur syndromet yttrar sig kliniskt skiljer sig något i beskrivningarna mellan människor och djur, men likheterna överväger vilket gör att man kan anta att samma patogenes föreligger hos människa och olika djurarter, inklusive vilda djur. 2015-05-08 First cycle, G2E NonPeerReviewed application/pdf sv https://stud.epsilon.slu.se/7926/11/thorsson_e_150512.pdf Thorsson, Elina, 2015. Hypertrophic osteoarthropathy in wildlife : and a review of suggested pathogeneses. First cycle, G2E. Uppsala: (VH) > Dept. of Biomedical Sciences and Veterinary Public Health (until 231231) <https://stud.epsilon.slu.se/view/divisions/OID-713.html> urn:nbn:se:slu:epsilon-s-4326 eng |
| spellingShingle | Animal diseases Thorsson, Elina Hypertrophic osteoarthropathy in wildlife |
| title | Hypertrophic osteoarthropathy in wildlife |
| title_full | Hypertrophic osteoarthropathy in wildlife |
| title_fullStr | Hypertrophic osteoarthropathy in wildlife |
| title_full_unstemmed | Hypertrophic osteoarthropathy in wildlife |
| title_short | Hypertrophic osteoarthropathy in wildlife |
| title_sort | hypertrophic osteoarthropathy in wildlife |
| topic | Animal diseases |
| url | https://stud.epsilon.slu.se/7926/ https://stud.epsilon.slu.se/7926/ |