Pulsed inhaled Nitric Oxide - a possible way to treat hypoxemia in colic horses during abdominal surgery
The aim of the present study was to evaluate if pulsed inhaled nitric oxide (PiNO) could be used as a treatment for hypoxemia during general anaesthesia in colic horses. Previous studies have shown a positive response in horses receiving PiNO in comparison to controls, but these studies have only in...
| Main Author: | |
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| Format: | Second cycle, A2E |
| Language: | Swedish Inglés |
| Published: |
2014
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| Online Access: | https://stud.epsilon.slu.se/6525/ |
| _version_ | 1855571026145968128 |
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| author | Wiklund, Maja |
| author_browse | Wiklund, Maja |
| author_facet | Wiklund, Maja |
| author_sort | Wiklund, Maja |
| collection | Epsilon Archive for Student Projects |
| description | The aim of the present study was to evaluate if pulsed inhaled nitric oxide (PiNO) could be used as a treatment for hypoxemia during general anaesthesia in colic horses. Previous studies have shown a positive response in horses receiving PiNO in comparison to controls, but these studies have only included healthy individuals. A total of 30 horses were included in this present study, they all underwent abdominal surgery because of acute colic that could not be medically treated. Fifteen of the horses received PiNO and 15 horses served as a control group. Arterial oxygenation was improved in all horses receiving PiNO. PaO2, SaO2, CaO2 and P(A-a)O2 increased as a result of a decrease in right to left vascular-shunt (Qs/Qt) due to the inhalation of NO. The conclusion is that PiNO is an effective way to treat hypoxemia in colic horses undergoing abdominal surgery. |
| format | Second cycle, A2E |
| id | RepoSLU6525 |
| institution | Swedish University of Agricultural Sciences |
| language | Swedish Inglés |
| publishDate | 2014 |
| publishDateSort | 2014 |
| record_format | eprints |
| spelling | RepoSLU65252014-03-21T14:44:09Z https://stud.epsilon.slu.se/6525/ Pulsed inhaled Nitric Oxide - a possible way to treat hypoxemia in colic horses during abdominal surgery Wiklund, Maja Animal diseases The aim of the present study was to evaluate if pulsed inhaled nitric oxide (PiNO) could be used as a treatment for hypoxemia during general anaesthesia in colic horses. Previous studies have shown a positive response in horses receiving PiNO in comparison to controls, but these studies have only included healthy individuals. A total of 30 horses were included in this present study, they all underwent abdominal surgery because of acute colic that could not be medically treated. Fifteen of the horses received PiNO and 15 horses served as a control group. Arterial oxygenation was improved in all horses receiving PiNO. PaO2, SaO2, CaO2 and P(A-a)O2 increased as a result of a decrease in right to left vascular-shunt (Qs/Qt) due to the inhalation of NO. The conclusion is that PiNO is an effective way to treat hypoxemia in colic horses undergoing abdominal surgery. Syftet med detta arbete var att utvärdera effekterna av pulsad inhalerad kvävemonoxid (PiNO) och se om det kan användas för att behandla hypoxemi under allmän narkos på kolikhästar. Tidigare studier har visat positiva effekter hos hästar som fått PiNO i jämförelse med kontroller, dessa studier har dock bara inkluderat friska individer. Totalt ingick 30 hästar i denna studie och alla dessa buköppnades på grund av akut kolik som inte gick att behandla medicinskt. Femton hästar fick PiNO under narkos och 15 hästar ingick i kontrollgruppen. Alla hästar som fick PiNO fick en förbättrad syresättning; de fick ökat syretryck (PaO2), ökad syremättnad (SaO2), ökat syreinnehåll i arteriellt blod (CaO2) och minskad alveolär-arteriell syredifferens (P(A-a)O2) vilket berodde på en minskad shunt (Qs/Qt) som var ett resultat av den inhalerade kvävemonoxiden. Slutsatsen är att PiNO är en effektiv metod för att behandla hypoxemi hos kolikhästar vid bukkirurgi. 2014-03-19 Second cycle, A2E NonPeerReviewed application/pdf sv https://stud.epsilon.slu.se/6525/7/wiklund_m_140319.pdf Wiklund, Maja, 2014. Pulsed inhaled Nitric Oxide - a possible way to treat hypoxemia in colic horses during abdominal surgery. Second cycle, A2E. Uppsala: (VH) > Dept. of Clinical Sciences (until 231231) <https://stud.epsilon.slu.se/view/divisions/OID-715.html> urn:nbn:se:slu:epsilon-s-3134 eng |
| spellingShingle | Animal diseases Wiklund, Maja Pulsed inhaled Nitric Oxide - a possible way to treat hypoxemia in colic horses during abdominal surgery |
| title | Pulsed inhaled Nitric Oxide - a possible way to treat hypoxemia in colic horses during abdominal surgery |
| title_full | Pulsed inhaled Nitric Oxide - a possible way to treat hypoxemia in colic horses during abdominal surgery |
| title_fullStr | Pulsed inhaled Nitric Oxide - a possible way to treat hypoxemia in colic horses during abdominal surgery |
| title_full_unstemmed | Pulsed inhaled Nitric Oxide - a possible way to treat hypoxemia in colic horses during abdominal surgery |
| title_short | Pulsed inhaled Nitric Oxide - a possible way to treat hypoxemia in colic horses during abdominal surgery |
| title_sort | pulsed inhaled nitric oxide - a possible way to treat hypoxemia in colic horses during abdominal surgery |
| topic | Animal diseases |
| url | https://stud.epsilon.slu.se/6525/ https://stud.epsilon.slu.se/6525/ |