Differences of progressive retinal atrophy in dogs
A group of diseases that affect the dog’s sight is progressive retinal atrophy (PRA) a disease that means that the photoreceptors in the retina of the eye either not develop normally or undergo degeneration and thereby causes vision loss and blindness. The disease affects many different breeds and i...
| Autor principal: | |
|---|---|
| Formato: | M2 |
| Lenguaje: | Inglés sueco |
| Publicado: |
SLU/Dept. of Animal Breeding and Genetics (until 231231)
2013
|
| Materias: |
| _version_ | 1855570888095694848 |
|---|---|
| author | Ekroth, Lisen |
| author_browse | Ekroth, Lisen |
| author_facet | Ekroth, Lisen |
| author_sort | Ekroth, Lisen |
| collection | Epsilon Archive for Student Projects |
| description | A group of diseases that affect the dog’s sight is progressive retinal atrophy (PRA) a disease that means that the photoreceptors in the retina of the eye either not develop normally or undergo degeneration and thereby causes vision loss and blindness. The disease affects many different breeds and is inherited. What have been shown is that it is different genes that had become mutated in the different breeds, this conclude that despite similar clinical symptoms, the underlying reason could be different. Also the genes that are mutated in dogs and give rise to diseases also exists in humans. In humans there is a big group of diseases that goes under the name Retinitis pigmentosa (RP) and it is equivalent to PRA. This is a review of the progression of the disease in both humans and dogs and also a comparison of the mutations that causes the diseases in dogs. |
| format | M2 |
| id | RepoSLU5705 |
| institution | Swedish University of Agricultural Sciences |
| language | Inglés swe |
| publishDate | 2013 |
| publishDateSort | 2013 |
| publisher | SLU/Dept. of Animal Breeding and Genetics (until 231231) |
| publisherStr | SLU/Dept. of Animal Breeding and Genetics (until 231231) |
| record_format | eprints |
| spelling | RepoSLU57052013-06-20T11:25:01Z Differences of progressive retinal atrophy in dogs Skillnader i progressiv retinal atrofi hos hund Ekroth, Lisen Atrophy Retina Dog PRA A group of diseases that affect the dog’s sight is progressive retinal atrophy (PRA) a disease that means that the photoreceptors in the retina of the eye either not develop normally or undergo degeneration and thereby causes vision loss and blindness. The disease affects many different breeds and is inherited. What have been shown is that it is different genes that had become mutated in the different breeds, this conclude that despite similar clinical symptoms, the underlying reason could be different. Also the genes that are mutated in dogs and give rise to diseases also exists in humans. In humans there is a big group of diseases that goes under the name Retinitis pigmentosa (RP) and it is equivalent to PRA. This is a review of the progression of the disease in both humans and dogs and also a comparison of the mutations that causes the diseases in dogs. En grupp av sjukdomar som drabbar hundars syn är progressiv retina atrophy (PRA), en sjukdom som innebär att fotoreceptorerna i ögats retina antingen inte utvecklas normalt eller genomgår en degeneration och därigenom orsakar synreduktion och blindhet. Sjukdomen drabbar många olika raser och är ärftlig. Det har visat sig att det är helt olika gener som drabbats av mutationer i de olika raserna så trots att sjukdomen har relativt likvärdiga kliniska symptom så kan den bakomliggande orsaken vara olika. Hos människor finns det en stor grupp sjukdomar som går under namnet Retinitis pigmentosa (RP) och är den homologa motsvarigheten till hundens PRA. Detta är en studie av sjukdomens förlopp hos både hund och människa samt en sammanställning av de mutationer som ligger till grund för sjukdomarna hos hund. SLU/Dept. of Animal Breeding and Genetics (until 231231) 2013 M2 eng swe https://stud.epsilon.slu.se/5705/ |
| spellingShingle | Atrophy Retina Dog PRA Ekroth, Lisen Differences of progressive retinal atrophy in dogs |
| title | Differences of progressive retinal atrophy in dogs |
| title_full | Differences of progressive retinal atrophy in dogs |
| title_fullStr | Differences of progressive retinal atrophy in dogs |
| title_full_unstemmed | Differences of progressive retinal atrophy in dogs |
| title_short | Differences of progressive retinal atrophy in dogs |
| title_sort | differences of progressive retinal atrophy in dogs |
| topic | Atrophy Retina Dog PRA |