Minor fieled study - molecular epidemiologi of rabies in Sao Paulo state and Minas Gerais state, Brazil

Rabies is a fatal zoonotic disease spread worldwide. The most common sources of infection for all animals and humans are bites from dogs or bats. The aim of this degree project was to diagnose and determine the source of infection for 11 rabies samples from São Paulo State and Minas Gerais State,...

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Autor principal: Torsson, Emeli
Formato: H2
Lenguaje:Inglés
sueco
Publicado: SLU/Dept. of Biomedical Sciences and Veterinary Public Health (until 231231) 2013
Materias:
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author Torsson, Emeli
author_browse Torsson, Emeli
author_facet Torsson, Emeli
author_sort Torsson, Emeli
collection Epsilon Archive for Student Projects
description Rabies is a fatal zoonotic disease spread worldwide. The most common sources of infection for all animals and humans are bites from dogs or bats. The aim of this degree project was to diagnose and determine the source of infection for 11 rabies samples from São Paulo State and Minas Gerais State, Brazil. Diagnosis was made through direct immunofluorescence assay, mouse inoculation and RT-PCR. The sources of infection were determined by sequencing 234 nucleotides of the 5’ end of the N-gene and align these with homologous sequences retrieved from GenBank. All seven samples for which satisfactory sequences could be achieved clustered with the sequences related to vampire bat with a bootstrap value of 98%.
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institution Swedish University of Agricultural Sciences
language Inglés
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publishDate 2013
publishDateSort 2013
publisher SLU/Dept. of Biomedical Sciences and Veterinary Public Health (until 231231)
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spelling RepoSLU52322013-01-29T10:47:06Z Minor fieled study - molecular epidemiologi of rabies in Sao Paulo state and Minas Gerais state, Brazil Minor Field study - molekylär epidemiologisk studie för rabies i Sao Paulo state and minas Gerais state, Brasilien Torsson, Emeli rabies epidemiology Brazil Rabies is a fatal zoonotic disease spread worldwide. The most common sources of infection for all animals and humans are bites from dogs or bats. The aim of this degree project was to diagnose and determine the source of infection for 11 rabies samples from São Paulo State and Minas Gerais State, Brazil. Diagnosis was made through direct immunofluorescence assay, mouse inoculation and RT-PCR. The sources of infection were determined by sequencing 234 nucleotides of the 5’ end of the N-gene and align these with homologous sequences retrieved from GenBank. All seven samples for which satisfactory sequences could be achieved clustered with the sequences related to vampire bat with a bootstrap value of 98%. Rabies är en dödlig zoonos som är spridd över hela världen. De vanligaste smittkällorna för djur och människor är bett från hundar eller fladdermöss. Målet med detta examensarbete var att diagnostisera och fastställa smittkällan för 11 rabiesprover från São Paulo State och Minas Gerais State, Brasilien. Diagnos ställdes via direkt immunofluorescens, musinokulering och RT-PCR. Smittkällan fastställdes via sekvensering av 234 nukleotider av 5´-delen på N-genen vilka jämfördes med homologa sekvenser hämtade från GenBank. Alla sju prover för vilka tillfredställande sekvenser gick att uppnå anhopades, med en sannolikhet på 98 %, inom de sekvenser som relateras till vampyrfladdermusen. SLU/Dept. of Biomedical Sciences and Veterinary Public Health (until 231231) 2013 H2 eng swe https://stud.epsilon.slu.se/5232/
spellingShingle rabies
epidemiology
Brazil
Torsson, Emeli
Minor fieled study - molecular epidemiologi of rabies in Sao Paulo state and Minas Gerais state, Brazil
title Minor fieled study - molecular epidemiologi of rabies in Sao Paulo state and Minas Gerais state, Brazil
title_full Minor fieled study - molecular epidemiologi of rabies in Sao Paulo state and Minas Gerais state, Brazil
title_fullStr Minor fieled study - molecular epidemiologi of rabies in Sao Paulo state and Minas Gerais state, Brazil
title_full_unstemmed Minor fieled study - molecular epidemiologi of rabies in Sao Paulo state and Minas Gerais state, Brazil
title_short Minor fieled study - molecular epidemiologi of rabies in Sao Paulo state and Minas Gerais state, Brazil
title_sort minor fieled study - molecular epidemiologi of rabies in sao paulo state and minas gerais state, brazil
topic rabies
epidemiology
Brazil