Infectious bronchitis in Brazil

Infectious Bronchitis (IB) is a highly contagious viral respiratory and production depressant disease distributed world wide. The disease is caused by the Infectious Bronchitis Virus (IBV), a positive RNA strand Avian Coronavirus within the genus Gammacoronavirus. Due to a combination of high mutati...

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Autor principal: Olofsson, Cecilia
Formato: Second cycle, A1N, A1F or AXX
Lenguaje:sueco
Inglés
Publicado: 2012
Materias:
Acceso en línea:https://stud.epsilon.slu.se/3940/
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author Olofsson, Cecilia
author_browse Olofsson, Cecilia
author_facet Olofsson, Cecilia
author_sort Olofsson, Cecilia
collection Epsilon Archive for Student Projects
description Infectious Bronchitis (IB) is a highly contagious viral respiratory and production depressant disease distributed world wide. The disease is caused by the Infectious Bronchitis Virus (IBV), a positive RNA strand Avian Coronavirus within the genus Gammacoronavirus. Due to a combination of high mutation rate and a tendency of recombination a constant emergence of new genotypes and serotypes is seen. In Brazil, a country with an extensive poultry production and major problems with disease control, the diversity of circulating strains are wide and outbreaks of clinical disease despite intensive use of vaccines are common. The aim of this study was to investigate the presence of IBV and to identify genotypes of isolated IBVs in a limited number of layer flocks in Bastos, São Paulo, as part of the screening for circulating genotypes in the country. As a minor part the Biosecurity measures (precautions) was observed. In addition, a literature study was performed on IB and IBV. Organ samples from four farms were collected as pools of trachea, lungs, kidneys, reproductive tract and enteric content and were analyzed using Reverse Transcriptase Polymerase Chain Reaction (RT-PCR). Over fifty percent of the samples were positive for IBV and three samples were identified as 4/91-genotype using Genotype-specific PCR. Due to problems with the RT-PCR that was targeting part of the S1-gene, the genotypes of the rest of the positive samples could not be determined using DNA sequencing. They were instead identified as not belonging to Massachusetts, D274 or 4/91 genotypes using Genotype-specific RT-PCR. Considering the results of previous studies in Brazil stating that a national Brazilian Variant dominates, the possibility that the unidentified genotypes belonged to the national genotype were considered high.
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spelling RepoSLU39402012-04-20T14:25:29Z https://stud.epsilon.slu.se/3940/ Infectious bronchitis in Brazil Olofsson, Cecilia Human medicine, health, and safety Infectious Bronchitis (IB) is a highly contagious viral respiratory and production depressant disease distributed world wide. The disease is caused by the Infectious Bronchitis Virus (IBV), a positive RNA strand Avian Coronavirus within the genus Gammacoronavirus. Due to a combination of high mutation rate and a tendency of recombination a constant emergence of new genotypes and serotypes is seen. In Brazil, a country with an extensive poultry production and major problems with disease control, the diversity of circulating strains are wide and outbreaks of clinical disease despite intensive use of vaccines are common. The aim of this study was to investigate the presence of IBV and to identify genotypes of isolated IBVs in a limited number of layer flocks in Bastos, São Paulo, as part of the screening for circulating genotypes in the country. As a minor part the Biosecurity measures (precautions) was observed. In addition, a literature study was performed on IB and IBV. Organ samples from four farms were collected as pools of trachea, lungs, kidneys, reproductive tract and enteric content and were analyzed using Reverse Transcriptase Polymerase Chain Reaction (RT-PCR). Over fifty percent of the samples were positive for IBV and three samples were identified as 4/91-genotype using Genotype-specific PCR. Due to problems with the RT-PCR that was targeting part of the S1-gene, the genotypes of the rest of the positive samples could not be determined using DNA sequencing. They were instead identified as not belonging to Massachusetts, D274 or 4/91 genotypes using Genotype-specific RT-PCR. Considering the results of previous studies in Brazil stating that a national Brazilian Variant dominates, the possibility that the unidentified genotypes belonged to the national genotype were considered high. 2012-03-05 Second cycle, A1N, A1F or AXX NonPeerReviewed application/pdf swe https://stud.epsilon.slu.se/3940/7/olofsson_c_%202012.pdf Olofsson, Cecilia, 2012. Infectious bronchitis in Brazil : a minor field study in Bastos municipality, Sao Paulo. Second cycle, A1N, A1F or AXX ( AXX). Uppsala: (VH) > Dept. of Biomedical Sciences and Veterinary Public Health (until 231231) <https://stud.epsilon.slu.se/view/divisions/OID-713.html> urn:nbn:se:slu:epsilon-s-984 eng
spellingShingle Human medicine, health, and safety
Olofsson, Cecilia
Infectious bronchitis in Brazil
title Infectious bronchitis in Brazil
title_full Infectious bronchitis in Brazil
title_fullStr Infectious bronchitis in Brazil
title_full_unstemmed Infectious bronchitis in Brazil
title_short Infectious bronchitis in Brazil
title_sort infectious bronchitis in brazil
topic Human medicine, health, and safety
url https://stud.epsilon.slu.se/3940/
https://stud.epsilon.slu.se/3940/