Potential aquatic bacterial pathogens in the Philippines and Thailand

Strains of Aeromonas spp., `non–cholera vibrios´(NCVs) and Plesiomonas shigelloides isolated from aquatic environments and fish and human diarrhoeal cases in the Philippines and Thailand were characterised for potential virulence markers, such as the production of cytotoxin, cell-associated and cell...

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Autor principal: Maluping, Ramon
Formato: Second cycle, A1N, A1F or AXX
Lenguaje:sueco
Inglés
Publicado: 2011
Materias:
Acceso en línea:https://stud.epsilon.slu.se/3598/
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author Maluping, Ramon
author_browse Maluping, Ramon
author_facet Maluping, Ramon
author_sort Maluping, Ramon
collection Epsilon Archive for Student Projects
description Strains of Aeromonas spp., `non–cholera vibrios´(NCVs) and Plesiomonas shigelloides isolated from aquatic environments and fish and human diarrhoeal cases in the Philippines and Thailand were characterised for potential virulence markers, such as the production of cytotoxin, cell-associated and cell-free haemolysin and their capacity to adhere to human intestinal (Henle 407) cells in vitro. In addition, the occurrence of tlh and tdh haemolysin genes and urease activity among Vibrio parahaemolyticus strains were also investigated. The antimicrobial susceptibility profile of these strains was identified with selected antibiotics used in human medicine and aquaculture. The minimum inhibitory concentration of ampicillin, ceftiofur, gentamicin, neomycin,streptomycin, enrofloxacin, florfenicol, oxytetracycline and trimethoprimsulphamethoxazole was determined using broth microdilution method. Susceptibility to imipenem and detection of extended-spectrum β-lactamases (ESBLs) in ampicillin resistant strains was achieved by the combination disc diffusion method. The results showed that strains recovered from clinical sources (human and fish)produced the investigated potential virulence determinants, while these are absent in environmental strains. Such virulence factors may be involved in the pathogenesis of disease caused by these bacterial pathogens in both humans and animals. Moreover, antimicrobial resistance among environmental strains was rare. Acquired resistance to tetracycline and fluoroquinolone was demonstrated in Aeromonas strains of clinical origin and it could be possible that acquired resistance is associated with the use of antimicrobials in therapy.
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spelling RepoSLU35982012-04-20T14:23:40Z https://stud.epsilon.slu.se/3598/ Potential aquatic bacterial pathogens in the Philippines and Thailand Maluping, Ramon Aquatic ecology Strains of Aeromonas spp., `non–cholera vibrios´(NCVs) and Plesiomonas shigelloides isolated from aquatic environments and fish and human diarrhoeal cases in the Philippines and Thailand were characterised for potential virulence markers, such as the production of cytotoxin, cell-associated and cell-free haemolysin and their capacity to adhere to human intestinal (Henle 407) cells in vitro. In addition, the occurrence of tlh and tdh haemolysin genes and urease activity among Vibrio parahaemolyticus strains were also investigated. The antimicrobial susceptibility profile of these strains was identified with selected antibiotics used in human medicine and aquaculture. The minimum inhibitory concentration of ampicillin, ceftiofur, gentamicin, neomycin,streptomycin, enrofloxacin, florfenicol, oxytetracycline and trimethoprimsulphamethoxazole was determined using broth microdilution method. Susceptibility to imipenem and detection of extended-spectrum β-lactamases (ESBLs) in ampicillin resistant strains was achieved by the combination disc diffusion method. The results showed that strains recovered from clinical sources (human and fish)produced the investigated potential virulence determinants, while these are absent in environmental strains. Such virulence factors may be involved in the pathogenesis of disease caused by these bacterial pathogens in both humans and animals. Moreover, antimicrobial resistance among environmental strains was rare. Acquired resistance to tetracycline and fluoroquinolone was demonstrated in Aeromonas strains of clinical origin and it could be possible that acquired resistance is associated with the use of antimicrobials in therapy. 2011-11-16 Second cycle, A1N, A1F or AXX NonPeerReviewed application/pdf swe https://stud.epsilon.slu.se/3598/1/maluping_r_p_111116.pdf Maluping, Ramon, 2004. Potential aquatic bacterial pathogens in the Philippines and Thailand : studies on the occurrence, characterisation, detection of potential virulence determinants and antimicrobial susceptibility profile. Second cycle, A1N, A1F or AXX ( AXX). Uppsala: (VH) > Dept. of Biomedical Sciences and Veterinary Public Health (until 231231) <https://stud.epsilon.slu.se/view/divisions/OID-713.html> urn:nbn:se:slu:epsilon-s-753 eng
spellingShingle Aquatic ecology
Maluping, Ramon
Potential aquatic bacterial pathogens in the Philippines and Thailand
title Potential aquatic bacterial pathogens in the Philippines and Thailand
title_full Potential aquatic bacterial pathogens in the Philippines and Thailand
title_fullStr Potential aquatic bacterial pathogens in the Philippines and Thailand
title_full_unstemmed Potential aquatic bacterial pathogens in the Philippines and Thailand
title_short Potential aquatic bacterial pathogens in the Philippines and Thailand
title_sort potential aquatic bacterial pathogens in the philippines and thailand
topic Aquatic ecology
url https://stud.epsilon.slu.se/3598/
https://stud.epsilon.slu.se/3598/