Rotavirus zoonotiska potential : kan infekterade föl smitta människa?

Rotavirus causes diarrhea in young mammals all over the world, including infant humans. The diarrhea leads to severe dehydration that can be fatal if left untreated. The dehydration can be treated with fluid therapy and the infection heals itself. Despite the relatively easy treatment half a million...

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Autor principal: Lassa, Emma
Formato: M2
Lenguaje:sueco
Inglés
Publicado: SLU/Dept. of Biomedical Sciences and Veterinary Public Health (until 231231) 2011
Materias:
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author Lassa, Emma
author_browse Lassa, Emma
author_facet Lassa, Emma
author_sort Lassa, Emma
collection Epsilon Archive for Student Projects
description Rotavirus causes diarrhea in young mammals all over the world, including infant humans. The diarrhea leads to severe dehydration that can be fatal if left untreated. The dehydration can be treated with fluid therapy and the infection heals itself. Despite the relatively easy treatment half a million children under the age of five dies every year due to diarrhea caused by rotavirus. Rotavirus sorts into the family Reoviridae and is a double-stranded RNA virus with a segmented genome. The segmentation allows re-assortment in cases of co-infection with different strains which quickly can give rise to new strains of rotavirus. The aim with this literature review was, beside describing rotavirus, to answer the questions: “Does rotaviruses have a zoonotic potential? Is it a risk for humans to be infected by foals carrying the virus?“. Several studies have shown that animals and humans have fallen ill and shedded rotavirus particles with a genome that consisted of a mix of genes from rotaviruses from different species. This, as well as cases where it has been proven that not only a few genes have been transferred, but whole virions, implicates that rotavirus has a zoonotic potential even though no large clinical outbreaks of disease in humans caused by animal rotavirus has yet been documented. Equine rotaviruses have been shown to be a homogenic group that in several aspects are different compared with the other groups of rotaviruses. However studies have found cases were equine rotavirus have re-assorted with porcine, bovine and human rotavirus strains. The conclusion is that there is a ground for concern that people working with horses might be infected with equine rotavirus.
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id RepoSLU3128
institution Swedish University of Agricultural Sciences
language swe
Inglés
publishDate 2011
publishDateSort 2011
publisher SLU/Dept. of Biomedical Sciences and Veterinary Public Health (until 231231)
publisherStr SLU/Dept. of Biomedical Sciences and Veterinary Public Health (until 231231)
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spelling RepoSLU31282012-04-20T14:21:56Z Rotavirus zoonotiska potential : kan infekterade föl smitta människa? Zoonotic potential of rotavirus : can infected foals transmit the disease to humans? Lassa, Emma rotavirus zoonos häst Rotavirus causes diarrhea in young mammals all over the world, including infant humans. The diarrhea leads to severe dehydration that can be fatal if left untreated. The dehydration can be treated with fluid therapy and the infection heals itself. Despite the relatively easy treatment half a million children under the age of five dies every year due to diarrhea caused by rotavirus. Rotavirus sorts into the family Reoviridae and is a double-stranded RNA virus with a segmented genome. The segmentation allows re-assortment in cases of co-infection with different strains which quickly can give rise to new strains of rotavirus. The aim with this literature review was, beside describing rotavirus, to answer the questions: “Does rotaviruses have a zoonotic potential? Is it a risk for humans to be infected by foals carrying the virus?“. Several studies have shown that animals and humans have fallen ill and shedded rotavirus particles with a genome that consisted of a mix of genes from rotaviruses from different species. This, as well as cases where it has been proven that not only a few genes have been transferred, but whole virions, implicates that rotavirus has a zoonotic potential even though no large clinical outbreaks of disease in humans caused by animal rotavirus has yet been documented. Equine rotaviruses have been shown to be a homogenic group that in several aspects are different compared with the other groups of rotaviruses. However studies have found cases were equine rotavirus have re-assorted with porcine, bovine and human rotavirus strains. The conclusion is that there is a ground for concern that people working with horses might be infected with equine rotavirus. SLU/Dept. of Biomedical Sciences and Veterinary Public Health (until 231231) 2011 M2 swe eng https://stud.epsilon.slu.se/3128/
spellingShingle rotavirus
zoonos
häst
Lassa, Emma
Rotavirus zoonotiska potential : kan infekterade föl smitta människa?
title Rotavirus zoonotiska potential : kan infekterade föl smitta människa?
title_full Rotavirus zoonotiska potential : kan infekterade föl smitta människa?
title_fullStr Rotavirus zoonotiska potential : kan infekterade föl smitta människa?
title_full_unstemmed Rotavirus zoonotiska potential : kan infekterade föl smitta människa?
title_short Rotavirus zoonotiska potential : kan infekterade föl smitta människa?
title_sort rotavirus zoonotiska potential : kan infekterade föl smitta människa?
topic rotavirus
zoonos
häst