Biomarkers in equine bone and joint disorders

The purpose with this literature study was to summarize the research on biomarkers in equine bone and joint diseases and to get more knowledge about how these markers are affected by the diseases, exercise, age, sex and breed. Bone and joint diseases are a common cause of loss of performance in the...

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Autor principal: Berg-Johansson, Johanna
Formato: First cycle, G2E
Lenguaje:sueco
Inglés
Publicado: 2009
Materias:
Acceso en línea:https://stud.epsilon.slu.se/236/
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author Berg-Johansson, Johanna
author_browse Berg-Johansson, Johanna
author_facet Berg-Johansson, Johanna
author_sort Berg-Johansson, Johanna
collection Epsilon Archive for Student Projects
description The purpose with this literature study was to summarize the research on biomarkers in equine bone and joint diseases and to get more knowledge about how these markers are affected by the diseases, exercise, age, sex and breed. Bone and joint diseases are a common cause of loss of performance in the athletic horse. Osteochondrosis (OC) is a disease of articular cartilage development and is a common cause of lameness in young horses, leading to decreased athletic potential. Osteoarthritis (OA) is characterized by damage to and loss of articular cartilage matrix components, along with reduced joint function. Disorders in horses have a large economical impact on the horse industry through loss of breeding potential and reduced market value of the affected horses. Disease prevention and pain reduction are general aims of animal welfare within animal husbandry. It would therefore be welcome with any improvement in prevention, diagnosis, treatment and prognostication in these areas and biomarkers may be helpful tools. Molecules that are normal products and byproducts of the metabolic processes that are taking place within the skeletal tissues are often used as markers. Biomarkers are good tools for the prediction and detection of diseases without performing major procedure on the horse. The research is not yet at a stage of having a “magic marker” to diagnose the degree of articular cartilage or bone disease in a single joint with 100% accuracy. Though, many biomarkers have the potential to predict and distinguish the diseases but more research is needed to get higher reliability of these markers.
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spelling RepoSLU2362012-04-20T14:08:40Z https://stud.epsilon.slu.se/236/ Biomarkers in equine bone and joint disorders Berg-Johansson, Johanna Animal diseases Animal physiology - Growth and development The purpose with this literature study was to summarize the research on biomarkers in equine bone and joint diseases and to get more knowledge about how these markers are affected by the diseases, exercise, age, sex and breed. Bone and joint diseases are a common cause of loss of performance in the athletic horse. Osteochondrosis (OC) is a disease of articular cartilage development and is a common cause of lameness in young horses, leading to decreased athletic potential. Osteoarthritis (OA) is characterized by damage to and loss of articular cartilage matrix components, along with reduced joint function. Disorders in horses have a large economical impact on the horse industry through loss of breeding potential and reduced market value of the affected horses. Disease prevention and pain reduction are general aims of animal welfare within animal husbandry. It would therefore be welcome with any improvement in prevention, diagnosis, treatment and prognostication in these areas and biomarkers may be helpful tools. Molecules that are normal products and byproducts of the metabolic processes that are taking place within the skeletal tissues are often used as markers. Biomarkers are good tools for the prediction and detection of diseases without performing major procedure on the horse. The research is not yet at a stage of having a “magic marker” to diagnose the degree of articular cartilage or bone disease in a single joint with 100% accuracy. Though, many biomarkers have the potential to predict and distinguish the diseases but more research is needed to get higher reliability of these markers. 2009-06-02 First cycle, G2E NonPeerReviewed application/pdf swe https://stud.epsilon.slu.se/236/1/bergjohansson_j_090602.pdf Berg-Johansson, Johanna, 2009. Biomarkers in equine bone and joint disorders. First cycle, G2E. Uppsala: (VH) > Dept. of Anatomy, Physiology and Biochemistry (until 231231) <https://stud.epsilon.slu.se/view/divisions/OID-712.html> urn:nbn:se:slu:epsilon-6-31 eng
spellingShingle Animal diseases
Animal physiology - Growth and development
Berg-Johansson, Johanna
Biomarkers in equine bone and joint disorders
title Biomarkers in equine bone and joint disorders
title_full Biomarkers in equine bone and joint disorders
title_fullStr Biomarkers in equine bone and joint disorders
title_full_unstemmed Biomarkers in equine bone and joint disorders
title_short Biomarkers in equine bone and joint disorders
title_sort biomarkers in equine bone and joint disorders
topic Animal diseases
Animal physiology - Growth and development
url https://stud.epsilon.slu.se/236/
https://stud.epsilon.slu.se/236/