How social behaviour in juvenile Brown trout (Salmo trutta) are regulated by social hierarchies and exposure to the benzodiazepine oxazepam
Improved global healthcare rises the production and consumption of human pharmaceuticals. Insufficient wastewater treatment systems and unregulated downstream impacts causes pharmaceutical contamination of surface waters with trace residues in countries covering all continents. Earlier studies of aq...
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| Formato: | M2 |
| Lenguaje: | Inglés sueco |
| Publicado: |
SLU/Dept. of Forest Ecology and Management
2022
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| Materias: |
| _version_ | 1855572974883569664 |
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| author | Johansson Kvarnström, Elin |
| author_browse | Johansson Kvarnström, Elin |
| author_facet | Johansson Kvarnström, Elin |
| author_sort | Johansson Kvarnström, Elin |
| collection | Epsilon Archive for Student Projects |
| description | Improved global healthcare rises the production and consumption of human pharmaceuticals. Insufficient wastewater treatment systems and unregulated downstream impacts causes pharmaceutical contamination of surface waters with trace residues in countries covering all continents. Earlier studies of aquatic systems have shown that pharmaceutical exposure influences fish physiology and causes behavioural responses at both individual and ecosystem level. Here, I evaluated how social status in juvenile brown trout (Salmo trutta) influenced behaviour after exposure to an anxiolytic drug (the benzodiazepine, oxazepam). For this project, the fish were exposed to one of three oxazepam treatments: one low, environmentally relevant dose, one high, human therapeutic relevant dose, and one control dose without oxazepam. I expected decreased aggressive behaviour and mitigated relations between dominant and subordinate individuals. Contrary to the prediction and to earlier documentation of fish behavioural responses to oxazepam exposure, neither of the treatments in this project resulted in altered social hierarchies. Moreover, there were no significant differences in brown trout aggression between the treatment groups. The interspecies variations and the relatively unexplored effects of pharmaceutical exposure on social behaviour motivates further studies, preferability over longer time periods with environmentally realistic contexts. This information should be used to improve pharmaceutical regulations and legislation for ecological risk assessments. |
| format | M2 |
| id | RepoSLU17915 |
| institution | Swedish University of Agricultural Sciences |
| language | Inglés swe |
| publishDate | 2022 |
| publishDateSort | 2022 |
| publisher | SLU/Dept. of Forest Ecology and Management |
| publisherStr | SLU/Dept. of Forest Ecology and Management |
| record_format | eprints |
| spelling | RepoSLU179152022-07-08T10:38:48Z How social behaviour in juvenile Brown trout (Salmo trutta) are regulated by social hierarchies and exposure to the benzodiazepine oxazepam Johansson Kvarnström, Elin Behaviour Brown trout Dominance Ecotoxicology Exposure Fish Oxazepam Pharmaceutical Salmo trutta Social status Improved global healthcare rises the production and consumption of human pharmaceuticals. Insufficient wastewater treatment systems and unregulated downstream impacts causes pharmaceutical contamination of surface waters with trace residues in countries covering all continents. Earlier studies of aquatic systems have shown that pharmaceutical exposure influences fish physiology and causes behavioural responses at both individual and ecosystem level. Here, I evaluated how social status in juvenile brown trout (Salmo trutta) influenced behaviour after exposure to an anxiolytic drug (the benzodiazepine, oxazepam). For this project, the fish were exposed to one of three oxazepam treatments: one low, environmentally relevant dose, one high, human therapeutic relevant dose, and one control dose without oxazepam. I expected decreased aggressive behaviour and mitigated relations between dominant and subordinate individuals. Contrary to the prediction and to earlier documentation of fish behavioural responses to oxazepam exposure, neither of the treatments in this project resulted in altered social hierarchies. Moreover, there were no significant differences in brown trout aggression between the treatment groups. The interspecies variations and the relatively unexplored effects of pharmaceutical exposure on social behaviour motivates further studies, preferability over longer time periods with environmentally realistic contexts. This information should be used to improve pharmaceutical regulations and legislation for ecological risk assessments. Sjukvården förbättras globalt vilket innebär en ökad produktion och konsumtion av läkemedel. I dagsläget är reningsverkens filtrering av avloppsvatten otillräckliga och spår av läkemedel har hittats i vattendrag över hela världen. Studier av akvatiska miljöer som kontaminerats av läkemedel har påvisat beteendeförändringar hos fiskar och andra vattenlevande organismer med konsekvenser på både individ- och ekosystemnivå. Under det här projektet utvärderade jag hur öringens (Salmo trutta) sociala status påverkar beteenden under exponering för ett anxiolytiskt läkemedel (bensodiazepinen oxazepam). Fiskarna exponerades för en av tre behandlingar av oxazepam: en låg dos som motsvarar koncentrationer som uppmätts i naturen, en hög och för människan terapeutiskt relevant dos, samt en kontrolldos utan oxazepam. Jag förväntade mig att exponerade fiskar skulle uppträda mindre aggressivt och att beteendeskillnader mellan dominanta och underordnade individer skulle mildras. I motsats till hypotesen och tidigare dokumentation av beteendeförändringar hos fiskar som exponerats för oxazepam resulterade ingen av behandlingarna i förändrade dominanshierarkier under detta projekt. Vidare fanns heller inga signifikanta skillnader i aggressivt beteende mellan behandlingsgrupperna. De relativt outforskade konsekvenserna av läkemedelsexponering på populations- och ekosystemnivå motiverar ytterligare studier, företrädesvis över längre tidsperioder och under miljömässigt realistiska förutsättningar. Informationen bör användas för att reglera hantering av läkemedel och vid framtida riskbedömningar av ekotoxikologiska effekter. SLU/Dept. of Forest Ecology and Management 2022 M2 eng swe https://stud.epsilon.slu.se/17915/ |
| spellingShingle | Behaviour Brown trout Dominance Ecotoxicology Exposure Fish Oxazepam Pharmaceutical Salmo trutta Social status Johansson Kvarnström, Elin How social behaviour in juvenile Brown trout (Salmo trutta) are regulated by social hierarchies and exposure to the benzodiazepine oxazepam |
| title | How social behaviour in juvenile Brown trout (Salmo trutta) are regulated by social hierarchies and exposure to the benzodiazepine oxazepam |
| title_full | How social behaviour in juvenile Brown trout (Salmo trutta) are regulated by social hierarchies and exposure to the benzodiazepine oxazepam |
| title_fullStr | How social behaviour in juvenile Brown trout (Salmo trutta) are regulated by social hierarchies and exposure to the benzodiazepine oxazepam |
| title_full_unstemmed | How social behaviour in juvenile Brown trout (Salmo trutta) are regulated by social hierarchies and exposure to the benzodiazepine oxazepam |
| title_short | How social behaviour in juvenile Brown trout (Salmo trutta) are regulated by social hierarchies and exposure to the benzodiazepine oxazepam |
| title_sort | how social behaviour in juvenile brown trout (salmo trutta) are regulated by social hierarchies and exposure to the benzodiazepine oxazepam |
| topic | Behaviour Brown trout Dominance Ecotoxicology Exposure Fish Oxazepam Pharmaceutical Salmo trutta Social status |