Clinical significance of Toxoplasma gondii in immunocompetent cats

Toxoplasma gondii is an obligate intracellular parasite, with felines as its definitive host and all warm-blooded mammals and birds as intermediate hosts. It is known that most infected hosts are asymptotic, especially cats are supposed to be able to develop a long-term immunity after first time inf...

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Autor principal: Lau, Wing Yin
Formato: M2
Lenguaje:Inglés
sueco
Publicado: SLU/Dept. of Biomedical Sciences and Veterinary Public Health (until 231231) 2018
Materias:
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author Lau, Wing Yin
author_browse Lau, Wing Yin
author_facet Lau, Wing Yin
author_sort Lau, Wing Yin
collection Epsilon Archive for Student Projects
description Toxoplasma gondii is an obligate intracellular parasite, with felines as its definitive host and all warm-blooded mammals and birds as intermediate hosts. It is known that most infected hosts are asymptotic, especially cats are supposed to be able to develop a long-term immunity after first time infection. Clinical toxoplasmosis is rare and occurs in patients that are usually immunosuppressed, this fact can make one be less alert about the significance of how T. gondii can potentially affect cats clinically in general, especially for those that are immunocompetent. Clinical toxoplasmosis is a serious disease that can be fatal to cats that do not receive adequate treatment in time as it can progress aggressively. The symptoms vary and are usually nonspecific; a few cases will be summarized in this paper. Most tests, when conducted alone, do not give conclusive information to make a definitive diagnosis. As toxoplasmosis is usually not included in the list of differential diagnosis when it comes to acute cases, because it occurs so rarely, so the running of diagnostic tests is often delayed. These factors pose a great challenge for clinicians to make an early and correct diagnosis which is the key for treatment.
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institution Swedish University of Agricultural Sciences
language Inglés
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publishDate 2018
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publisher SLU/Dept. of Biomedical Sciences and Veterinary Public Health (until 231231)
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spelling RepoSLU140972019-02-25T13:06:16Z Clinical significance of Toxoplasma gondii in immunocompetent cats Lau, Wing Yin Toxoplasma gondii toxoplasmos katt immunokompetent Toxoplasma gondii is an obligate intracellular parasite, with felines as its definitive host and all warm-blooded mammals and birds as intermediate hosts. It is known that most infected hosts are asymptotic, especially cats are supposed to be able to develop a long-term immunity after first time infection. Clinical toxoplasmosis is rare and occurs in patients that are usually immunosuppressed, this fact can make one be less alert about the significance of how T. gondii can potentially affect cats clinically in general, especially for those that are immunocompetent. Clinical toxoplasmosis is a serious disease that can be fatal to cats that do not receive adequate treatment in time as it can progress aggressively. The symptoms vary and are usually nonspecific; a few cases will be summarized in this paper. Most tests, when conducted alone, do not give conclusive information to make a definitive diagnosis. As toxoplasmosis is usually not included in the list of differential diagnosis when it comes to acute cases, because it occurs so rarely, so the running of diagnostic tests is often delayed. These factors pose a great challenge for clinicians to make an early and correct diagnosis which is the key for treatment. Toxoplasma gondii är en intracellulär parasit som har kattdjur som sin slutgiltiga värd och alla varmblodiga däggdjur och fåglar som mellanvärd. De flesta infekterade värdarna visar inga symptom, speciellt katter som kan utveckla en långvarig immunitet efter den första infektionen. Klinisk toxoplasmos är sällsynt och förekommer vanligt hos patienter som är immunnedsatta. Detta faktum kan göra att man är mindre uppmärksam på hur T. gondii kan påverka katterna kliniskt generellt, särskilt för de som är immunokompetenta. Klinisk toxoplasmos är en allvarlig sjukdom som kan vara dödlig för katter som inte får adekvat behandling i tid då det kan utvecklas aggressivt. Symtomen varierar och är vanligtvis ospecifika; några kliniska fall sammanfattas i denna uppsats. De flesta tester ger inte avgörande resultat för att ställa en slutgiltig diagnos, och veterinärer misstänker inte sjukdomen tillräckligt tidigt för att testa för parasiten. Dessa faktorer utgör en stor utmaning för kliniker att göra en tidig och korrekt diagnos som är nyckeln till behandling. SLU/Dept. of Biomedical Sciences and Veterinary Public Health (until 231231) 2018 M2 eng swe https://stud.epsilon.slu.se/14097/
spellingShingle Toxoplasma gondii
toxoplasmos
katt
immunokompetent
Lau, Wing Yin
Clinical significance of Toxoplasma gondii in immunocompetent cats
title Clinical significance of Toxoplasma gondii in immunocompetent cats
title_full Clinical significance of Toxoplasma gondii in immunocompetent cats
title_fullStr Clinical significance of Toxoplasma gondii in immunocompetent cats
title_full_unstemmed Clinical significance of Toxoplasma gondii in immunocompetent cats
title_short Clinical significance of Toxoplasma gondii in immunocompetent cats
title_sort clinical significance of toxoplasma gondii in immunocompetent cats
topic Toxoplasma gondii
toxoplasmos
katt
immunokompetent