Progesteronrelaterad diabetes mellitus hos älghund
Diabetes mellitus (DM) is a relatively common endocrine disease in dogs and is more common in certain breeds than others, e.g. Nordic spitz breeds. Within the Swedish and Norwegian Elkhound population, female dogs are almost exclusively affected. The hypothesis in this study is that Swedish- and Nor...
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| Formato: | Otro |
| Lenguaje: | sueco sueco |
| Publicado: |
2009
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| Acceso en línea: | https://stud.epsilon.slu.se/11796/ |
| _version_ | 1855571941172183040 |
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| author | Wallberg, Annelie |
| author_browse | Wallberg, Annelie |
| author_facet | Wallberg, Annelie |
| author_sort | Wallberg, Annelie |
| collection | Epsilon Archive for Student Projects |
| description | Diabetes mellitus (DM) is a relatively common endocrine disease in dogs and is more common in certain breeds than others, e.g. Nordic spitz breeds. Within the Swedish and Norwegian Elkhound population, female dogs are almost exclusively affected. The hypothesis in this study is that Swedish- and Norwegian Elkhounds develop DM during the progesterone phase of estrous (diestrous or pregnancy).
Medical records from 51 female dogs of the breeds Swedish and Norwegian Elkhound were studied. All cases derived from the Canine Diabetes Mellitus Project at the University of Agricultural Sciences (SLU) up to July 2008. The dogs were followed in average 2,8 months (range one day to 37 months). The study shows that the dogs develop DM in progesterone phase (diestrous or pregnancy). The study also showed that in several cases, remission of the disease was obtained after ovariohysterectomi of the dogs. Moreover, it was indicated that the best chance for remission was if the time lap from the start of clinical signs until performance of the ovariohysterectomi became as short as possible. Thus, the recommendation is to perform an ovariohysterectomi as soon as possible after confirmation of the diagnosis.
Insulin and progesterone concentrations were measured in 15 female dogs with DM and 15 healthy female dogs. The study showed no significant difference in either insulin or progesterone concentrations between sick and healthy female dogs. However, the study showed that most of the female dogs with DM still had insulin production at the time of diagnosis. The insulin concentrations in dogs with DM showed a tendency to be higher at the beginning of the progesterone phase. Further studies with increased number of dogs would be of interest in order to further evaluate differences in both insulin and progesterone concentrations in female elkhounds. |
| format | Otro |
| id | RepoSLU11796 |
| institution | Swedish University of Agricultural Sciences |
| language | Swedish swe |
| publishDate | 2009 |
| publishDateSort | 2009 |
| record_format | eprints |
| spelling | RepoSLU117962017-10-17T07:26:35Z https://stud.epsilon.slu.se/11796/ Progesteronrelaterad diabetes mellitus hos älghund Wallberg, Annelie Veterinary science and hygiene - General aspects Diabetes mellitus (DM) is a relatively common endocrine disease in dogs and is more common in certain breeds than others, e.g. Nordic spitz breeds. Within the Swedish and Norwegian Elkhound population, female dogs are almost exclusively affected. The hypothesis in this study is that Swedish- and Norwegian Elkhounds develop DM during the progesterone phase of estrous (diestrous or pregnancy). Medical records from 51 female dogs of the breeds Swedish and Norwegian Elkhound were studied. All cases derived from the Canine Diabetes Mellitus Project at the University of Agricultural Sciences (SLU) up to July 2008. The dogs were followed in average 2,8 months (range one day to 37 months). The study shows that the dogs develop DM in progesterone phase (diestrous or pregnancy). The study also showed that in several cases, remission of the disease was obtained after ovariohysterectomi of the dogs. Moreover, it was indicated that the best chance for remission was if the time lap from the start of clinical signs until performance of the ovariohysterectomi became as short as possible. Thus, the recommendation is to perform an ovariohysterectomi as soon as possible after confirmation of the diagnosis. Insulin and progesterone concentrations were measured in 15 female dogs with DM and 15 healthy female dogs. The study showed no significant difference in either insulin or progesterone concentrations between sick and healthy female dogs. However, the study showed that most of the female dogs with DM still had insulin production at the time of diagnosis. The insulin concentrations in dogs with DM showed a tendency to be higher at the beginning of the progesterone phase. Further studies with increased number of dogs would be of interest in order to further evaluate differences in both insulin and progesterone concentrations in female elkhounds. Diabetes mellitus (DM) är en relativt vanlig endokrin sjukdom hos hund och är vanligare hos vissa raser än andra, däribland våra nordiska spetsraser. Hos älghund (jämt- och gråhundar) är de som drabbas nästan uteslutande tikar. Huvudfrågeställningen i denna studie är huruvida tikar av jämt- och gråhundsras får sin DM i progesteronfas (diöstrus eller dräktighet) eller jämt spritt under året. Journaler från 51 tikar av älghundsras med diagnos DM studerades. Samtliga studerade tikar ingick i Hunddiabetesprojektet vid Sveriges Lantbruksuniversitet (SLU) till och med juli 2008. Hundarna följdes i genomsnitt 2,8 månader (range en dag till 37 månader). Studien visar att dessa tikar drabbas av DM i progesteronfas (diöstrus eller dräktighet). Studien indikerar också att största förutsättningen till remission av sjukdomen är att tiden från symtomdebut till kastration blir så kort som möjligt. Som veterinär är det därför viktigt att upplysa djurägare till älghundstikar om vikten av att vara observant på symtom samt att tidigt kontakta veterinär. Så snart diagnos har säkerställts bör snar kastration av tiken förespråkas. Insulin- och progesteronkoncentrationer mättes i serum hos 15 sjuka tikar med diagnos DM och 15 friska tikar. Resultaten från studien visade ingen signifikant skillnad avseende vare sig insulin- eller progesteronkoncentrationer mellan sjuka och friska tikar. Det visade sig emellertid att insulinproduktion fanns kvar hos flertalet av de sjuka tikarna vid diagnostillfället. Insulinkoncentrationerna visade även tendens till att ligga högre i början av progesteronfasen hos de sjuka tikarna. Materialet var litet vilket gav en låg power (chans att hitta skillnader). Vidare studier med fler individer skulle därför vara av värde för att visa på eventuella skillnader i både insulin- och progesteronkoncentrationerna hos älghundstikar. 2009-02-02 Other NonPeerReviewed application/pdf sv https://stud.epsilon.slu.se/11796/1/wallberg_a_171017.pdf Wallberg, Annelie, 2009. Progesteronrelaterad diabetes mellitus hos älghund. UNSPECIFIED, Uppsala. Uppsala: (VH) > Dept. of Clinical Sciences (until 231231) <https://stud.epsilon.slu.se/view/divisions/OID-715.html> urn:nbn:se:slu:epsilon-s-7893 swe |
| spellingShingle | Veterinary science and hygiene - General aspects Wallberg, Annelie Progesteronrelaterad diabetes mellitus hos älghund |
| title | Progesteronrelaterad diabetes mellitus hos älghund |
| title_full | Progesteronrelaterad diabetes mellitus hos älghund |
| title_fullStr | Progesteronrelaterad diabetes mellitus hos älghund |
| title_full_unstemmed | Progesteronrelaterad diabetes mellitus hos älghund |
| title_short | Progesteronrelaterad diabetes mellitus hos älghund |
| title_sort | progesteronrelaterad diabetes mellitus hos älghund |
| topic | Veterinary science and hygiene - General aspects |
| url | https://stud.epsilon.slu.se/11796/ https://stud.epsilon.slu.se/11796/ |