Bärarskap av meticillinresistent Staphylococcus pseudintermedius (MRSP) hos svenska hundar
During the last years, meticillin resistant Staphylococcus pseudintermedius (MRSP) have caused an increasing number of infections in Swedish dogs. MRSP is resistant against a majority of the antimicrobials available for dogs in Sweden, making it difficult to treat the infection. Our knowledge of the...
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| Formato: | Otro |
| Lenguaje: | sueco sueco |
| Publicado: |
2009
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| Acceso en línea: | https://stud.epsilon.slu.se/11789/ |
| _version_ | 1855571939783868416 |
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| author | Reimegård, Elin |
| author_browse | Reimegård, Elin |
| author_facet | Reimegård, Elin |
| author_sort | Reimegård, Elin |
| collection | Epsilon Archive for Student Projects |
| description | During the last years, meticillin resistant Staphylococcus pseudintermedius (MRSP) have caused an increasing number of infections in Swedish dogs. MRSP is resistant against a majority of the antimicrobials available for dogs in Sweden, making it difficult to treat the infection. Our knowledge of the bacterium is limited, making it hard to handle infected dogs in a proper way. The aim of this study was to investigate for how long time dogs, who have an infection caused by MRSP, become carriers of the bacterium. Other factors like treatment with antimicrobials, the correlation between clinical symptoms and carriage, common diagnoses and institutionalization where also looked upon. Increased knowledge in this field will improve the handling of patients and the advises to owners.
Bacterial swabs where sampled from 23 Swedish dogs with known carriage of MRSP. Samples where collected on two occasions from four different locations: the nose, around anus, the pharynx and from any infected area on the dog. If the dog was asymptomatic, samples were instead taken from lip commissures. Culturing and identificationing and antimicrobial susceptibility tests were carried out in compliance with chosen method. Oxacillin resistant colonies where indirectly tested for the presence of the mecA gene with latexagglutination and this is used to confirm it as a MRSP.
Among the 23 dogs that where sampled, almost 86 % where still positive within one to five months time. After six to thirteen months, almost 77 % of the dogs were sampled negative for MRSP. MRSP was isolated from one dog 12 months after it was first diagnosed. All of the dogs had been treated with antimicrobials within three months prior to MRSP culture. Among the dogs that tested positive for MRSP both dogs with and without clinical symptoms of infections where found. Above all, two diagnoses where prominent in the study; post operative wound infections and pyoderma. All of the dogs had been treated at veterinary clinics and 16 of 23 dogs had been hospitalised more than two nights.
Rigourous hygiene routines are imperative in preventing spread of infection. Prudent use of antimicrobials and increased bacterial sampling, including resistance patterns, are further steps essential in reducing the selection for MRSP. |
| format | Otro |
| id | RepoSLU11789 |
| institution | Swedish University of Agricultural Sciences |
| language | Swedish swe |
| publishDate | 2009 |
| publishDateSort | 2009 |
| record_format | eprints |
| spelling | RepoSLU117892017-10-17T08:56:28Z https://stud.epsilon.slu.se/11789/ Bärarskap av meticillinresistent Staphylococcus pseudintermedius (MRSP) hos svenska hundar Reimegård, Elin Veterinary science and hygiene - General aspects During the last years, meticillin resistant Staphylococcus pseudintermedius (MRSP) have caused an increasing number of infections in Swedish dogs. MRSP is resistant against a majority of the antimicrobials available for dogs in Sweden, making it difficult to treat the infection. Our knowledge of the bacterium is limited, making it hard to handle infected dogs in a proper way. The aim of this study was to investigate for how long time dogs, who have an infection caused by MRSP, become carriers of the bacterium. Other factors like treatment with antimicrobials, the correlation between clinical symptoms and carriage, common diagnoses and institutionalization where also looked upon. Increased knowledge in this field will improve the handling of patients and the advises to owners. Bacterial swabs where sampled from 23 Swedish dogs with known carriage of MRSP. Samples where collected on two occasions from four different locations: the nose, around anus, the pharynx and from any infected area on the dog. If the dog was asymptomatic, samples were instead taken from lip commissures. Culturing and identificationing and antimicrobial susceptibility tests were carried out in compliance with chosen method. Oxacillin resistant colonies where indirectly tested for the presence of the mecA gene with latexagglutination and this is used to confirm it as a MRSP. Among the 23 dogs that where sampled, almost 86 % where still positive within one to five months time. After six to thirteen months, almost 77 % of the dogs were sampled negative for MRSP. MRSP was isolated from one dog 12 months after it was first diagnosed. All of the dogs had been treated with antimicrobials within three months prior to MRSP culture. Among the dogs that tested positive for MRSP both dogs with and without clinical symptoms of infections where found. Above all, two diagnoses where prominent in the study; post operative wound infections and pyoderma. All of the dogs had been treated at veterinary clinics and 16 of 23 dogs had been hospitalised more than two nights. Rigourous hygiene routines are imperative in preventing spread of infection. Prudent use of antimicrobials and increased bacterial sampling, including resistance patterns, are further steps essential in reducing the selection for MRSP. De senaste åren har ett ökat antal fall av infektioner orsakade av meticillinresistenta Staphylococcus pseudintermedius (MRSP) drabbat hundar i Sverige. MRSP är resistent mot en stor del av de antibiotika som används till hundar i Sverige idag, något som gör den svårbehandlad om en infektion tillstöter. Vår kunskap om bakterien har varit begränsad och detta har gjort hanteringen av smittade hundar svår. Syftet med studien var att undersöka hur länge hundar som haft en infektion orsakad av MRSP (meticillinresistent Staphylococcus pseudintermedius) blir bärare av bakterien. Vi tittade även på andra faktorer i samband med smitta såsom antibiotikabehandling, korrelation mellan kliniska symptom och bärarskap, vanliga diagnoser hos smittad hund samt stationärvårdsbehandling som riskfaktor. Med ökad kunskap om hur bakterien beter sig kan hantering i samband med besök på djursjukhus och rådgivning till djurägare förbättras. Bakterieprover togs från 23 svenska hundar med tidigare känt bärarskap av MRSP. Prover togs vid två upprepade tillfällen från fyra olika lokalisationer på hunden; nos, perianalt, svalg samt infekterat område på hunden, och om inget sådant fanns togs provet från mungipan. Odling, typning och resistensbestämning utfördes enligt gängse metod vid SVA (Statens Veterinärmedicinska Anstalt). Oxacillinresistenta kolonier testades indirekt för förekomst av mecA-genen med hjälp av latexagglutination. De som var positiva benämndes som en MRSP. Av de hundar som provtogs en till fem månader från det att MRSP påvisats första gången var närmare 86 % positiva. Bland de hundar som provtogs sex till tretton månader från det att MRSP påvisats första gången testades ca 77 % negativa. En hund provtogs, och befanns vara positiv avseende 12 månader efter att den diagnosticerades första gången. Samtliga hundar hade blivit behandlade med antibiotika inom tre månader före det att MRSP påvisades första gången. Inget samband mellan kliniska symptom och smitta kunde påvisas. Bland de hundar som ingick i studien kunde framför allt två diagnoser urskiljas; infekterade operationssår och pyodermier (hudinfektioner). Alla hundar i studien hade besökt veterinärkliniker och 16 av 23 hundar hade stationärvårdsbehandlats i mer än två dagar före den första provtagningen som påvisande MRSP. Skärpta hygienrutiner, utökad bakterieprovtagning med resistensbestämning och ansvarsfull antibiotikaanvändning är väsentliga åtgärder för att förebygga selektion och spridning av MRSP. 2009-01-12 Other NonPeerReviewed application/pdf sv https://stud.epsilon.slu.se/11789/1/reimegard_e_171017.pdf Reimegård, Elin, 2009. Bärarskap av meticillinresistent Staphylococcus pseudintermedius (MRSP) hos svenska hundar. UNSPECIFIED, Uppsala. Uppsala: (VH) > Dept. of Clinical Sciences (until 231231) <https://stud.epsilon.slu.se/view/divisions/OID-715.html> urn:nbn:se:slu:epsilon-s-7900 swe |
| spellingShingle | Veterinary science and hygiene - General aspects Reimegård, Elin Bärarskap av meticillinresistent Staphylococcus pseudintermedius (MRSP) hos svenska hundar |
| title | Bärarskap av meticillinresistent Staphylococcus pseudintermedius (MRSP) hos svenska hundar |
| title_full | Bärarskap av meticillinresistent Staphylococcus pseudintermedius (MRSP) hos svenska hundar |
| title_fullStr | Bärarskap av meticillinresistent Staphylococcus pseudintermedius (MRSP) hos svenska hundar |
| title_full_unstemmed | Bärarskap av meticillinresistent Staphylococcus pseudintermedius (MRSP) hos svenska hundar |
| title_short | Bärarskap av meticillinresistent Staphylococcus pseudintermedius (MRSP) hos svenska hundar |
| title_sort | bärarskap av meticillinresistent staphylococcus pseudintermedius (mrsp) hos svenska hundar |
| topic | Veterinary science and hygiene - General aspects |
| url | https://stud.epsilon.slu.se/11789/ https://stud.epsilon.slu.se/11789/ |