Kronisk mitralisinsufficiens hos hund
Myxomatous mitral valve disease is a common disease in older dogs of small- to medium-size breeds. The mitral valve, and less commonly the tricuspid valve may be affected which causes them to leak blood from the ventricle to the atrium of the heart during systole. With increasing severity of mitral...
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| Formato: | Otro |
| Lenguaje: | sueco sueco |
| Publicado: |
2008
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| Acceso en línea: | https://stud.epsilon.slu.se/11772/ |
| _version_ | 1855571936081346560 |
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| author | Blom, Lena |
| author_browse | Blom, Lena |
| author_facet | Blom, Lena |
| author_sort | Blom, Lena |
| collection | Epsilon Archive for Student Projects |
| description | Myxomatous mitral valve disease is a common disease in older dogs of small- to medium-size breeds. The mitral valve, and less commonly the tricuspid valve may be affected which causes them to leak blood from the ventricle to the atrium of the heart during systole. With increasing severity of mitral valve leakage the forward stroke volume ejected into the aorta decreases, which may lead to an increase in blood pressure in the pulmonary vein resulting in pulmonary edema. A decrease in cardiac output may lead to a decrease in blood pressure, but the body may respond in order to normalize the blood pressure. Franzén showed in 2007 that the systolic blood pressure was increased in dogs with severe mitral insufficiency. Franzén used the intensity of the heart murmur to estimate the severity of mitral insufficiency. In this study we used echocardiography for the same purpose. Both studies used an oscillometric method to determine the arterial blood pressure. We wanted to see if we could obtain similar results using an echocardiographic classification. The aim of the study was to give an overview of the disease and investigate if mitral valve insufficiency affects the arterial blood pressure.
We examined a total of 58 dogs (20 male and 38 female) of which 53 had different severity of mitral insufficiency and 5 were healthy controls. The dogs comprised 51 cavalier king charles spaniels, 4 dachshunds, one poodle, one miniature schnauzer and one shih-tzu. The dogs were 2,2-15,6 years old with a mean age of 8,8 years. The female dogs were 2,2-15,1 years old with a mean age of 8,6 years. The male dogs were 3,7-15,6 years old with a mean age of 9,2 years.
The dogs underwent a physical examination and the heart rate, body weight and presence and intensity of heart murmur was recorded. The dog's systolic and diastolic blood pressure was measured using oscillometry and echocardiography was performed to determine the severity of mitral insufficiency.
The heart rate increased with increasing severity of mitral insufficiency. The diastolic blood pressure increased with increasing body weight. The results from our study showed that the severity of mitral insufficiency was not significantly associated with the arterial blood pressure. |
| format | Otro |
| id | RepoSLU11772 |
| institution | Swedish University of Agricultural Sciences |
| language | Swedish swe |
| publishDate | 2008 |
| publishDateSort | 2008 |
| record_format | eprints |
| spelling | RepoSLU117722017-10-17T11:03:47Z https://stud.epsilon.slu.se/11772/ Kronisk mitralisinsufficiens hos hund Blom, Lena Veterinary science and hygiene - General aspects Myxomatous mitral valve disease is a common disease in older dogs of small- to medium-size breeds. The mitral valve, and less commonly the tricuspid valve may be affected which causes them to leak blood from the ventricle to the atrium of the heart during systole. With increasing severity of mitral valve leakage the forward stroke volume ejected into the aorta decreases, which may lead to an increase in blood pressure in the pulmonary vein resulting in pulmonary edema. A decrease in cardiac output may lead to a decrease in blood pressure, but the body may respond in order to normalize the blood pressure. Franzén showed in 2007 that the systolic blood pressure was increased in dogs with severe mitral insufficiency. Franzén used the intensity of the heart murmur to estimate the severity of mitral insufficiency. In this study we used echocardiography for the same purpose. Both studies used an oscillometric method to determine the arterial blood pressure. We wanted to see if we could obtain similar results using an echocardiographic classification. The aim of the study was to give an overview of the disease and investigate if mitral valve insufficiency affects the arterial blood pressure. We examined a total of 58 dogs (20 male and 38 female) of which 53 had different severity of mitral insufficiency and 5 were healthy controls. The dogs comprised 51 cavalier king charles spaniels, 4 dachshunds, one poodle, one miniature schnauzer and one shih-tzu. The dogs were 2,2-15,6 years old with a mean age of 8,8 years. The female dogs were 2,2-15,1 years old with a mean age of 8,6 years. The male dogs were 3,7-15,6 years old with a mean age of 9,2 years. The dogs underwent a physical examination and the heart rate, body weight and presence and intensity of heart murmur was recorded. The dog's systolic and diastolic blood pressure was measured using oscillometry and echocardiography was performed to determine the severity of mitral insufficiency. The heart rate increased with increasing severity of mitral insufficiency. The diastolic blood pressure increased with increasing body weight. The results from our study showed that the severity of mitral insufficiency was not significantly associated with the arterial blood pressure. Kronisk mitralisinsufficiens (tidigare benämnt endokardos) är en vanligt förekommande hjärtsjukdom hos medelålders till äldre hundar och ses framförallt hos små- till medelstora raser. Sjukdomen innebär att mitralisklaffen, och ibland även tricuspidalisklaffen, degenereras och blir otät. Detta leder till att blod strömmar tillbaka från kammaren in i förmaket under systole. I grava fall minskar slagvolymen ut i aorta och blod stasas i lungvenen, vilket i sin tur leder till lungödem. Kroppen aktiverar då kompensatoriska mekanismer som strävar efter att normalisera blodtrycket. Franzén visade 2007 en signifikant ökning av det systoliska blodtrycket vid ökande läckage över mitralisklaffarna hos hund med kronisk mitralisinsufficiens. Hon använde sig av graden av blåsljud för att uppskatta graden av mitralisinsufficiens samt oscillometri för att mäta det arteriella blodtrycket. I denna studie användes ekokardiografi för att gradera mitralisinsufficiensen och oscillometri för att mäta det arteriella blodtrycket. Vi ville se om man erhöll samma resultat med de olika metoderna. Syftet med studien var att ge en överblick av sjukdomen samt att undersöka om det fanns ett samband mellan graden av mitralisinsufficiens och det arteriella blodtrycket. Vi undersökte sammanlagt 58 hundar (20 hanhundar och 38 tikar), varav 53 med varierande grad av kronisk mitralisinsufficiens samt 5 friska kontrollhundar. Det var framförallt hundar av rasen cavalier king charles spaniel (51 stycken) som inkluderades, men även en storpudel, en dvärgschnauzer, en shih-tzu och fyra taxar. Hundarna (samtliga) var mellan 2,2 och 15,6 år gamla med ett medelvärde på 8,8 år. Tikarna var mellan 2,2 och 15,1 år gamla med ett medelvärde på 8,6 år. Hanarna var mellan 3,7 och 15,6 år med ett medelvärde på 9,2 år. Hundarna genomgick en allmän klinisk undersökning för att fastställa hjärtfrekvens och grad av blåsljud. Oscillometri användes för att mäta det systoliska- och diastoliska blodtrycket och ekokardiografi för att bestämma hjärtstorlek samt graden av mitralisinsufficiens. Vår studie visade en statistiskt signifikant ökning av hjärtfrekvensen när graden av mitralisinsufficiens ökade. En ökad kroppsvikt gav en statistiskt signifikant ökning av det diastoliska blodtrycket. Denna studie kunde inte påvisa ett samband mellan graden av mitralisinsufficiens och det arteriella blodtrycket. 2008-05-23 Other NonPeerReviewed application/pdf sv https://stud.epsilon.slu.se/11772/1/blom_l_171017.pdf Blom, Lena, 2008. Kronisk mitralisinsufficiens hos hund : samband mellan graden av klaffinsufficiens och det arteriella blodtrycket. UNSPECIFIED, Uppsala. Uppsala: (VH) > Dept. of Clinical Sciences (until 231231) <https://stud.epsilon.slu.se/view/divisions/OID-715.html> urn:nbn:se:slu:epsilon-s-7917 swe |
| spellingShingle | Veterinary science and hygiene - General aspects Blom, Lena Kronisk mitralisinsufficiens hos hund |
| title | Kronisk mitralisinsufficiens hos hund |
| title_full | Kronisk mitralisinsufficiens hos hund |
| title_fullStr | Kronisk mitralisinsufficiens hos hund |
| title_full_unstemmed | Kronisk mitralisinsufficiens hos hund |
| title_short | Kronisk mitralisinsufficiens hos hund |
| title_sort | kronisk mitralisinsufficiens hos hund |
| topic | Veterinary science and hygiene - General aspects |
| url | https://stud.epsilon.slu.se/11772/ https://stud.epsilon.slu.se/11772/ |