Effect of metabolism cage housing on rodent welfare

The metabolic cage is developed to be able to have a control of total intake of feed and water and the excretion with urine and faeces. In addition, one can efficiently collect non contaminated samples of urine and faeces. For the animal, housing in a metabolic cage involves isolation and problems w...

Descripción completa

Detalles Bibliográficos
Autor principal: Tarland, Emilia
Formato: Otro
Lenguaje:sueco
Inglés
Publicado: 2007
Materias:
Acceso en línea:https://stud.epsilon.slu.se/11715/
_version_ 1855571924853194752
author Tarland, Emilia
author_browse Tarland, Emilia
author_facet Tarland, Emilia
author_sort Tarland, Emilia
collection Epsilon Archive for Student Projects
description The metabolic cage is developed to be able to have a control of total intake of feed and water and the excretion with urine and faeces. In addition, one can efficiently collect non contaminated samples of urine and faeces. For the animal, housing in a metabolic cage involves isolation and problems with cage enrichment since that can interfere with the total collection of urine and faeces. However little research has been done to investigate possible welfare problems for rodents placed in metabolic cages. Housing rodents socially isolated may lead to elevated corticosterone levels and more vulnerability to stress compared to group housed individuals. Studies have also found changes in the central nervous system and the immune system in individually housed rodents. Several negative effects of housing on grid floor are documented e.g. lesions and nerve injury in the hind feet of rats, elevated blood pressure, heart rate and body temperature. Especially mice show a strong preference for nesting material and lack of such may be stressful. More research on the effects of metabolism cage housing on rodent welfare are needed to develop a metabolic cage which enables sampling of uncontaminated urine while allowing the animals to perform their natural behaviours.
format Otro
id RepoSLU11715
institution Swedish University of Agricultural Sciences
language Swedish
Inglés
publishDate 2007
publishDateSort 2007
record_format eprints
spelling RepoSLU117152017-11-23T11:39:08Z https://stud.epsilon.slu.se/11715/ Effect of metabolism cage housing on rodent welfare Tarland, Emilia Animal physiology and biochemistry The metabolic cage is developed to be able to have a control of total intake of feed and water and the excretion with urine and faeces. In addition, one can efficiently collect non contaminated samples of urine and faeces. For the animal, housing in a metabolic cage involves isolation and problems with cage enrichment since that can interfere with the total collection of urine and faeces. However little research has been done to investigate possible welfare problems for rodents placed in metabolic cages. Housing rodents socially isolated may lead to elevated corticosterone levels and more vulnerability to stress compared to group housed individuals. Studies have also found changes in the central nervous system and the immune system in individually housed rodents. Several negative effects of housing on grid floor are documented e.g. lesions and nerve injury in the hind feet of rats, elevated blood pressure, heart rate and body temperature. Especially mice show a strong preference for nesting material and lack of such may be stressful. More research on the effects of metabolism cage housing on rodent welfare are needed to develop a metabolic cage which enables sampling of uncontaminated urine while allowing the animals to perform their natural behaviours. Metabolismburar är framtagna för att kunna studera totalintag och utsöndring (metabolism) av olika ämnen, göra totaluppsamlingar av urin och faeces samt kunna ta okontaminerade prov av urin och faeces. Det har däremot gjorts lite forskning för att påvisa eventuella välfärdsproblem hos gnagare placerade i metabolismburar. Gnagare hållna socialt isolerade kan få förhöjda nivåer av kortikosteron och bli mer känsliga för stress jämfört med grupphållna individer. Studier har också funnit förändringar i det centrala nervsystemet och immunsystemet hos individuellt hållna gnagare. Det finns flera dokumenterade negativa effekter av galler golv som t.ex. sår och nervskador i råttors baktassar, förhöjt blodtryck, förhöjd hjärtfrekvens och kroppstemperatur. Speciellt möss visar en stark preferens för bäddmaterial och avsaknad på detta kan vara stressframkallande. Det behövs mer forskning på hur hållning i metabolismburar kan påverka gnagares välfärd så att en metabolismbur som både ger okontaminerade prov av urin och faeces och tillåter djuren att utföra sina naturliga beteenden, kan utvecklas. 2007-09-28 Other NonPeerReviewed application/pdf sv https://stud.epsilon.slu.se/11715/1/tarland_e_171123.pdf Tarland, Emilia, 2007. Effect of metabolism cage housing on rodent welfare. UNSPECIFIED, Uppsala. Uppsala: (VH) > Dept. of Clinical Sciences (until 231231) <https://stud.epsilon.slu.se/view/divisions/OID-715.html> urn:nbn:se:slu:epsilon-s-9066 eng
spellingShingle Animal physiology and biochemistry
Tarland, Emilia
Effect of metabolism cage housing on rodent welfare
title Effect of metabolism cage housing on rodent welfare
title_full Effect of metabolism cage housing on rodent welfare
title_fullStr Effect of metabolism cage housing on rodent welfare
title_full_unstemmed Effect of metabolism cage housing on rodent welfare
title_short Effect of metabolism cage housing on rodent welfare
title_sort effect of metabolism cage housing on rodent welfare
topic Animal physiology and biochemistry
url https://stud.epsilon.slu.se/11715/
https://stud.epsilon.slu.se/11715/