Effekt på östralcykeln hos ston tillförda GnRH-analogen deslorelin (Ovuplant)
This article starts with a review of the literature regarding the normal reproductive physiology of the mare, prolonged luteal phase and medical drugs used within reproduction of the horse, with emphasis on Ovuplant®. The purpose of this article was to measure the progesterone level in blood, of mar...
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| Format: | L3 |
| Language: | Swedish Inglés |
| Published: |
SLU/Dept. of Clinical Sciences (until 231231)
2007
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| Subjects: |
| _version_ | 1855571918544961536 |
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| author | Tormalm, Ingeborg |
| author_browse | Tormalm, Ingeborg |
| author_facet | Tormalm, Ingeborg |
| author_sort | Tormalm, Ingeborg |
| collection | Epsilon Archive for Student Projects |
| description | This article starts with a review of the literature regarding the normal reproductive physiology of the mare, prolonged luteal phase and medical drugs used within reproduction of the horse, with emphasis on Ovuplant®. The purpose of this article was to measure the progesterone level in blood, of mares implanted with deslorelin acetate (Ovuplant®). The study was performed at the Department of Clinical Sciences, SLU, in Uppsala. There were seven mares included in the study. They were divided into two groups, one experimental group (four mares) and one control group (three mares). Ovuplant® was implanted subcutaneous in the four mares in the experimental group and physiological saline solution was injected in the three mares in the control group. Progesterone level in the blood was thereafter measured three times a week of a period of three months.
The result of the study showed that all mares of the control group had high level of progesterone in the blood for 24 (one mare, the luteal phase was interrupted with PGF2α) and at least 45 days (three mares), respectively. The mares in the control group had all normal cycles.
The conclusion of the study is that Ovuplant® can cause prolonged luteal phase and could be a future way to treat mares with strong oestrous symptoms. |
| format | L3 |
| id | RepoSLU11683 |
| institution | Swedish University of Agricultural Sciences |
| language | swe Inglés |
| publishDate | 2007 |
| publishDateSort | 2007 |
| publisher | SLU/Dept. of Clinical Sciences (until 231231) |
| publisherStr | SLU/Dept. of Clinical Sciences (until 231231) |
| record_format | eprints |
| spelling | RepoSLU116832017-11-24T08:29:05Z Effekt på östralcykeln hos ston tillförda GnRH-analogen deslorelin (Ovuplant) Tormalm, Ingeborg östralcykeln deslorelin Ovuplant This article starts with a review of the literature regarding the normal reproductive physiology of the mare, prolonged luteal phase and medical drugs used within reproduction of the horse, with emphasis on Ovuplant®. The purpose of this article was to measure the progesterone level in blood, of mares implanted with deslorelin acetate (Ovuplant®). The study was performed at the Department of Clinical Sciences, SLU, in Uppsala. There were seven mares included in the study. They were divided into two groups, one experimental group (four mares) and one control group (three mares). Ovuplant® was implanted subcutaneous in the four mares in the experimental group and physiological saline solution was injected in the three mares in the control group. Progesterone level in the blood was thereafter measured three times a week of a period of three months. The result of the study showed that all mares of the control group had high level of progesterone in the blood for 24 (one mare, the luteal phase was interrupted with PGF2α) and at least 45 days (three mares), respectively. The mares in the control group had all normal cycles. The conclusion of the study is that Ovuplant® can cause prolonged luteal phase and could be a future way to treat mares with strong oestrous symptoms. Uppsatsen börjar med en litteraturstudie som tar upp normal reproduktionsfysiologi, förlängd lutealfas och läkemedel som används inom hästreproduktion, med tyngdpunkt på Ovuplant® . Syftet med studien var att mäta progesteronnivåerna i blodet hos ston implanterade med deslorelinacetat (Ovuplant® ) subkutant. Studien utfördes på institutionen för kliniska vetenskaper vid SLU, Uppsala. I försöket ingick sju varmblodiga travarston som genom lottning delades in i en försöksgrupp (fyra ston) och en kontrollgrupp (tre ston). Ovuplant® implanterades subkutant på de fyra ston som ingick i försöksgruppen och fysiologisk koksaltlösning injicerades på de tre stona i kontrollgruppen. Därefter uppmättes progesteronnivåerna i blodet tre dagar i veckan under en period av ca 3 månader. Studien visade att alla ston som fått Ovuplant® implanterat subkutant visade förhöjda nivåer av progesteron i blodet i 24 (ett sto, lutealfasen avslutad med PGF2α) respektive minst 45 (tre ston) dagar. De ston som ingick i kontrollgruppen hade alla normala cykler. Slutsatsen av studien blir att Ovuplant® kan ge upphov till förlängd lutealfas och kan vara en möjlig behandlingsmetod för ston med problembrunster. SLU/Dept. of Clinical Sciences (until 231231) 2007 L3 swe eng https://stud.epsilon.slu.se/11683/ |
| spellingShingle | östralcykeln deslorelin Ovuplant Tormalm, Ingeborg Effekt på östralcykeln hos ston tillförda GnRH-analogen deslorelin (Ovuplant) |
| title | Effekt på östralcykeln hos ston tillförda GnRH-analogen deslorelin (Ovuplant) |
| title_full | Effekt på östralcykeln hos ston tillförda GnRH-analogen deslorelin (Ovuplant) |
| title_fullStr | Effekt på östralcykeln hos ston tillförda GnRH-analogen deslorelin (Ovuplant) |
| title_full_unstemmed | Effekt på östralcykeln hos ston tillförda GnRH-analogen deslorelin (Ovuplant) |
| title_short | Effekt på östralcykeln hos ston tillförda GnRH-analogen deslorelin (Ovuplant) |
| title_sort | effekt på östralcykeln hos ston tillförda gnrh-analogen deslorelin (ovuplant) |
| topic | östralcykeln deslorelin Ovuplant |