Prevalens av subkliniskt smittade katter med vingelsjuka i Göteborg jämfört med Uppsala
Borna disease virus (BDV) is a virus with capability to cause neurological disease in several species of mammals and of ostriches. Also humans are suspected to be susceptible to the virus, as the viral RNA and antibodies against BDV have been found in some humans with psychiatric diseases, like...
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| Formato: | Otro |
| Lenguaje: | sueco sueco |
| Publicado: |
2005
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| Materias: | |
| Acceso en línea: | https://stud.epsilon.slu.se/11529/ |
| _version_ | 1855571889994334208 |
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| author | Eriksson, Jonas |
| author_browse | Eriksson, Jonas |
| author_facet | Eriksson, Jonas |
| author_sort | Eriksson, Jonas |
| collection | Epsilon Archive for Student Projects |
| description | Borna disease virus (BDV) is a virus with capability to cause neurological
disease in several species of mammals and of ostriches. Also humans are
suspected to be susceptible to the virus, as the viral RNA and antibodies against
BDV have been found in some humans with psychiatric diseases, like
schizophrenia and depression. In Sweden there is a disease called staggering
disease in cats, associated to BDV-infection. This disease often has a fatal
progress. Definite diagnosis is reached by histo-pathological and
immunohistochemical examination of the central nervous system. In these cats, a
nonsuppurative meningoencephalomyelitis is induced by the virus. The disease
gives rise to signs like ataxia of the hind limbs, changes in behavior, inability to
withdraw the claws, mostly in the hind limbs and to pain from the lumbosacral
spine. In Sweden, apart from cats there have also been reported Borna-infection in
horses and lynx. The way of infection is not clearly understood, but there are
theories that rodents and some birds may work as naturally reservoirs of BDV. In
Sweden there is evidence that staggering disease in cats occurs in the region of
Mälardalen. There is however no larger studies made for the rest of Sweden.
Blood samples were collected in Gothenburg and Uppsala to study the prevalence
of antibodies against BDV in healthy, outdoor cats that were more than one year
of age. Realtime-PCR and ELISA-studies were performed. More studies are
needed to make the diagnostics to work and to be able to study the prevalence of
BDV in cats outside the region of Mälardalen. |
| format | Otro |
| id | RepoSLU11529 |
| institution | Swedish University of Agricultural Sciences |
| language | Swedish swe |
| publishDate | 2005 |
| publishDateSort | 2005 |
| record_format | eprints |
| spelling | RepoSLU115292017-10-03T10:45:10Z https://stud.epsilon.slu.se/11529/ Prevalens av subkliniskt smittade katter med vingelsjuka i Göteborg jämfört med Uppsala Eriksson, Jonas Veterinary science and hygiene - General aspects Faculty of Veterinary Medicine and Animal Science Borna disease virus (BDV) is a virus with capability to cause neurological disease in several species of mammals and of ostriches. Also humans are suspected to be susceptible to the virus, as the viral RNA and antibodies against BDV have been found in some humans with psychiatric diseases, like schizophrenia and depression. In Sweden there is a disease called staggering disease in cats, associated to BDV-infection. This disease often has a fatal progress. Definite diagnosis is reached by histo-pathological and immunohistochemical examination of the central nervous system. In these cats, a nonsuppurative meningoencephalomyelitis is induced by the virus. The disease gives rise to signs like ataxia of the hind limbs, changes in behavior, inability to withdraw the claws, mostly in the hind limbs and to pain from the lumbosacral spine. In Sweden, apart from cats there have also been reported Borna-infection in horses and lynx. The way of infection is not clearly understood, but there are theories that rodents and some birds may work as naturally reservoirs of BDV. In Sweden there is evidence that staggering disease in cats occurs in the region of Mälardalen. There is however no larger studies made for the rest of Sweden. Blood samples were collected in Gothenburg and Uppsala to study the prevalence of antibodies against BDV in healthy, outdoor cats that were more than one year of age. Realtime-PCR and ELISA-studies were performed. More studies are needed to make the diagnostics to work and to be able to study the prevalence of BDV in cats outside the region of Mälardalen. Bornavirus (Borna disease virus, BDV) är ett virus som kan orsaka en neurologisk sjukdom hos flera arter av däggdjur samt hos struts. Även människa misstänks kunna drabbas av viruset, då viralt RNA samt antikroppar mot BDV har kunnat påvisas hos en del människor med psykiatriska sjukdomar, såsom schizofreni och depression. I Sverige förekommer en hos katt neurologisk sjukdom, som kallas vingelsjuka. Denna sjukdom har ofta dödlig utgång. Definitiv diagnos fås efter histopatologisk och immunohistokemisk undersökning av hjärna och ryggmärg. Viruset ger upphov till en icke-purulent meningoencefalit hos katt. Sjukdomen ger symptom i form av vinglig gång i bakbenen, beteendeförändringar, oförmåga att dra in klorna, framförallt på bakbenen samt genom smärta från kors- och ländrygg. Vingelsjuka orsakas av BDV och förutom hos katter har bornavirusinfektion även rapporterats hos hästar och lodjur i Sverige. Smittvägen är inte helt klarlagd, men misstanke finns att gnagare och vissa fåglar fungerar som naturliga reservoarer för BDV. I Sverige är det klarlagt att det finns vingelsjuka på katt i Mälarregionen. Dock är inga större undersökningar gjorda för övriga Sverige. Blodprover togs i Göteborg och Uppsala för att kunna undersökas för prevalens av antikroppar mot BDV hos friska utekatter mer än ett år gamla. Realtids-PCR och ELISA-undersökning utfördes, dock utan att få fram hållbara resultat. Fler studier behövs för att diagnostiken skall fungera och för att kunna undersöka förekomst av BDV hos katter utanför Mälarregionen. 2005-02-03 Other NonPeerReviewed application/pdf sv https://stud.epsilon.slu.se/11529/1/eriksson_j_171003.pdf Eriksson, Jonas, 2005. Prevalens av subkliniskt smittade katter med vingelsjuka i Göteborg jämfört med Uppsala. UNSPECIFIED, Uppsala. Uppsala: (VH) > Dept. of Biomedical Sciences and Veterinary Public Health (until 231231) <https://stud.epsilon.slu.se/view/divisions/OID-713.html> urn:nbn:se:slu:epsilon-s-7439 swe |
| spellingShingle | Veterinary science and hygiene - General aspects Faculty of Veterinary Medicine and Animal Science Eriksson, Jonas Prevalens av subkliniskt smittade katter med vingelsjuka i Göteborg jämfört med Uppsala |
| title | Prevalens av subkliniskt smittade katter med vingelsjuka i Göteborg jämfört med Uppsala |
| title_full | Prevalens av subkliniskt smittade katter med vingelsjuka i Göteborg jämfört med Uppsala |
| title_fullStr | Prevalens av subkliniskt smittade katter med vingelsjuka i Göteborg jämfört med Uppsala |
| title_full_unstemmed | Prevalens av subkliniskt smittade katter med vingelsjuka i Göteborg jämfört med Uppsala |
| title_short | Prevalens av subkliniskt smittade katter med vingelsjuka i Göteborg jämfört med Uppsala |
| title_sort | prevalens av subkliniskt smittade katter med vingelsjuka i göteborg jämfört med uppsala |
| topic | Veterinary science and hygiene - General aspects Faculty of Veterinary Medicine and Animal Science |
| url | https://stud.epsilon.slu.se/11529/ https://stud.epsilon.slu.se/11529/ |