Mast cell tryptase, a potent inflammatory mediator, requires heparin for enzymatic activation

Mast cell tryptase, a tetrameric serine protease stored in mast cell granules in complex with heparin proteoglycan or chondroitin sulphate proteoglycan, is an important effector molecule in inflammatory reactions like allergies and asthma. In this study we have investigated the requirements for acti...

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Bibliographic Details
Main Author: Lindahl, Susanne
Format: L3
Language:Inglés
Swedish
Published: SLU/Dept. of Molecular Biosciences 2007
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