High quality draft genome of Brucella abortus strain Col-B012, isolated from a Holstein cattle in Nariño Colombia, brings new insights into the diagnosis and the epidemiology of biovar 4 strains
Brucellosis is a commonly diagnosed zoonosis that causes infertility and abortion in cattle, it is acquired from handling of infected animals or consuming contaminated milk or milk products. In Colombia, it is classified as prevention and control disease, despite its relevance little is known abo...
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Peerj
2024
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| Acceso en línea: | https://peerj.com/preprints/3416/ http://hdl.handle.net/20.500.12324/39731 |
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RepoAGROSAVIA39731 |
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dspace |
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Corporación Colombiana de Investigación Agropecuaria |
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Repositorio AGROSAVIA |
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Inglés |
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Brucellosis Biovar Genome Diagnosis Coparative genomics Enfermedades de los animales - L73 Ganado bovino Enfermedades de los animales Brucelosis Epidemiología Ganadería y especies menores http://aims.fao.org/aos/agrovoc/c_1391 http://aims.fao.org/aos/agrovoc/c_426 http://aims.fao.org/aos/agrovoc/c_1122 http://aims.fao.org/aos/agrovoc/c_2615 |
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Brucellosis Biovar Genome Diagnosis Coparative genomics Enfermedades de los animales - L73 Ganado bovino Enfermedades de los animales Brucelosis Epidemiología Ganadería y especies menores http://aims.fao.org/aos/agrovoc/c_1391 http://aims.fao.org/aos/agrovoc/c_426 http://aims.fao.org/aos/agrovoc/c_1122 http://aims.fao.org/aos/agrovoc/c_2615 Pacheco Montealegre, Mauricio Patiño Burbano, Rocio Esperanza Torres Higuera, Ligia Denise Jimenez Velasquez, Sabrina del Carmen Rodriguez Vitola, Jose Luis Caro Quintero, Alejandro High quality draft genome of Brucella abortus strain Col-B012, isolated from a Holstein cattle in Nariño Colombia, brings new insights into the diagnosis and the epidemiology of biovar 4 strains |
| description |
Brucellosis is a commonly diagnosed zoonosis that causes infertility and abortion
in cattle, it is acquired from handling of infected animals or consuming
contaminated milk or milk products. In Colombia, it is classified as prevention and
control disease, despite its relevance little is known about the origin,
epidemiology and the genetic constituents of the strains circulating in dairy farms.
Here we present the draft genome of B. abortus Col-B012, an isolate obtained
from a female Holstein belonging to a dairy farm in Nariño, Colombia. This
genome comprises 3,234,714 bp and 3,018 predicted protein-encoding genes.
Using comparative genomics and phylogenetic analysis, we found that the strain
Col-B012 clustered with known biovar 4 variants. The analysis of the core genesallowed the identification of polymorphisms only present in biovar 4 genomes,
these alleles might be associated with the phenotypic and pathogenic
characteristics of the group and are proposed as possible targets for
identification by PCR. The sequencing of B. abortus Col-B012 genome provides
important insights to improve the diagnosis and the epidemiology of this disease
and represents the first report of the biovar 4 in Colombia. |
| author2 |
Matthew, Jackson |
| author_facet |
Matthew, Jackson Pacheco Montealegre, Mauricio Patiño Burbano, Rocio Esperanza Torres Higuera, Ligia Denise Jimenez Velasquez, Sabrina del Carmen Rodriguez Vitola, Jose Luis Caro Quintero, Alejandro |
| format |
article |
| author |
Pacheco Montealegre, Mauricio Patiño Burbano, Rocio Esperanza Torres Higuera, Ligia Denise Jimenez Velasquez, Sabrina del Carmen Rodriguez Vitola, Jose Luis Caro Quintero, Alejandro |
| author_sort |
Pacheco Montealegre, Mauricio |
| title |
High quality draft genome of Brucella abortus strain Col-B012, isolated from a Holstein cattle in Nariño Colombia, brings new insights into the diagnosis and the epidemiology of biovar 4 strains |
| title_short |
High quality draft genome of Brucella abortus strain Col-B012, isolated from a Holstein cattle in Nariño Colombia, brings new insights into the diagnosis and the epidemiology of biovar 4 strains |
| title_full |
High quality draft genome of Brucella abortus strain Col-B012, isolated from a Holstein cattle in Nariño Colombia, brings new insights into the diagnosis and the epidemiology of biovar 4 strains |
| title_fullStr |
High quality draft genome of Brucella abortus strain Col-B012, isolated from a Holstein cattle in Nariño Colombia, brings new insights into the diagnosis and the epidemiology of biovar 4 strains |
| title_full_unstemmed |
High quality draft genome of Brucella abortus strain Col-B012, isolated from a Holstein cattle in Nariño Colombia, brings new insights into the diagnosis and the epidemiology of biovar 4 strains |
| title_sort |
high quality draft genome of brucella abortus strain col-b012, isolated from a holstein cattle in nariño colombia, brings new insights into the diagnosis and the epidemiology of biovar 4 strains |
| publisher |
Peerj |
| publishDate |
2024 |
| url |
https://peerj.com/preprints/3416/ http://hdl.handle.net/20.500.12324/39731 |
| work_keys_str_mv |
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RepoAGROSAVIA397312024-08-01T03:00:54Z High quality draft genome of Brucella abortus strain Col-B012, isolated from a Holstein cattle in Nariño Colombia, brings new insights into the diagnosis and the epidemiology of biovar 4 strains High quality draft genome of Brucella abortus strain Col-B012, isolated from a Holstein cattle in Nariño Colombia, brings new insights into the diagnosis and the epidemiology of biovar 4 strains Pacheco Montealegre, Mauricio Patiño Burbano, Rocio Esperanza Torres Higuera, Ligia Denise Jimenez Velasquez, Sabrina del Carmen Rodriguez Vitola, Jose Luis Caro Quintero, Alejandro Matthew, Jackson Brucellosis Biovar Genome Diagnosis Coparative genomics Enfermedades de los animales - L73 Ganado bovino Enfermedades de los animales Brucelosis Epidemiología Ganadería y especies menores http://aims.fao.org/aos/agrovoc/c_1391 http://aims.fao.org/aos/agrovoc/c_426 http://aims.fao.org/aos/agrovoc/c_1122 http://aims.fao.org/aos/agrovoc/c_2615 Brucellosis is a commonly diagnosed zoonosis that causes infertility and abortion in cattle, it is acquired from handling of infected animals or consuming contaminated milk or milk products. In Colombia, it is classified as prevention and control disease, despite its relevance little is known about the origin, epidemiology and the genetic constituents of the strains circulating in dairy farms. Here we present the draft genome of B. abortus Col-B012, an isolate obtained from a female Holstein belonging to a dairy farm in Nariño, Colombia. This genome comprises 3,234,714 bp and 3,018 predicted protein-encoding genes. Using comparative genomics and phylogenetic analysis, we found that the strain Col-B012 clustered with known biovar 4 variants. The analysis of the core genesallowed the identification of polymorphisms only present in biovar 4 genomes, these alleles might be associated with the phenotypic and pathogenic characteristics of the group and are proposed as possible targets for identification by PCR. The sequencing of B. abortus Col-B012 genome provides important insights to improve the diagnosis and the epidemiology of this disease and represents the first report of the biovar 4 in Colombia. Ministerio de Agricultura y Desarrollo Rural - MADR Ganadería bovina 2024-07-31T14:41:28Z 2024-07-31T14:41:28Z 2017-11-17 2017 article Artículo científico http://purl.org/coar/resource_type/c_2df8fbb1 info:eu-repo/semantics/article https://purl.org/redcol/resource_type/ART http://purl.org/coar/version/c_970fb48d4fbd8a85 https://peerj.com/preprints/3416/ 2167-8359 http://hdl.handle.net/20.500.12324/39731 10.7287/peerj.preprints.3416v1 reponame:Biblioteca Digital Agropecuaria de Colombia instname:Corporación colombiana de investigación agropecuaria AGROSAVIA eng Peerj 1 1 1 27 Garin-Bastuji, B. Brucelloses bovine, ovine et caprine: Contrôle et prevention. Le Point vétérinaire: revue d'enseignement post-universitaie et de formation permanente, 1993; 25: 15-22. 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