Development and Genome-Wide Analysis of a Blast-Resistant japonica Rice Variety

Rice is one of the most important crops in the world, and its production is severely affected by the rice blast disease caused by the fungus Magnaporthe oryzae. Several major blast resistance genes and QTLs associated with blast resistance have been described and mostly identified in indica rice...

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Autores principales: Escolà, Glòria, González-Miguel, Víctor M., Campo, Sonia, Catala-Forner, Mar, Domingo, Concha, Marqués, Luis, San Segundo, Blanca
Formato: article
Lenguaje:Inglés
Publicado: MDPI 2024
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Acceso en línea:https://hdl.handle.net/20.500.11939/8915
https://www.mdpi.com/2223-7747/12/20/3536
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author Escolà, Glòria
González-Miguel, Víctor M.
Campo, Sonia
Catala-Forner, Mar
Domingo, Concha
Marqués, Luis
San Segundo, Blanca
author_browse Campo, Sonia
Catala-Forner, Mar
Domingo, Concha
Escolà, Glòria
González-Miguel, Víctor M.
Marqués, Luis
San Segundo, Blanca
author_facet Escolà, Glòria
González-Miguel, Víctor M.
Campo, Sonia
Catala-Forner, Mar
Domingo, Concha
Marqués, Luis
San Segundo, Blanca
author_sort Escolà, Glòria
collection ReDivia
description Rice is one of the most important crops in the world, and its production is severely affected by the rice blast disease caused by the fungus Magnaporthe oryzae. Several major blast resistance genes and QTLs associated with blast resistance have been described and mostly identified in indica rice varieties. In this work, we report the obtention of a blast-resistant rice breeding line derived from crosses between the resistant indica variety CT13432 and the japonica elite cultivar JSendra (highly susceptible to blast). The breeding line, named COPSEMAR9, was found to exhibit resistance to leaf blast and panicle blast, as demonstrated by disease assays under controlled and field conditions. Furthermore, a high-quality genome sequence of the blast-resistant breeding line was obtained using a strategy that combines short-read sequencing (Illumina sequencing) and long-read sequencing (Pacbio sequencing). The use of a whole-genome approach allowed the fine mapping of DNA regions of indica and japonica origin present in the COPSEMAR9 genome and the identification of parental gene regions potentially contributing to blast resistance in the breeding line. Rice blast resistance genes (including Pi33 derived from the resistant parent) and defense-related genes in the genome of COPSEMAR9 were identified. Whole-genome analyses also revealed the presence of microRNAs (miRNAs) with a known function in the rice response to M. oryzae infection in COPSEMAR9, which might also contribute to its phenotype of blast resistance. From this study, the genomic information and analysis methods provide valuable knowledge that will be useful in breeding programs for blast resistance in japonica rice cultivars.
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spelling ReDivia89152025-04-25T14:49:37Z Development and Genome-Wide Analysis of a Blast-Resistant japonica Rice Variety Escolà, Glòria González-Miguel, Víctor M. Campo, Sonia Catala-Forner, Mar Domingo, Concha Marqués, Luis San Segundo, Blanca Genome mapping Japonica Magnaporthe oryzae MicroRNA Resistance F30 Plant genetics and breeding Breeding Defense response Oryza sativa Rice is one of the most important crops in the world, and its production is severely affected by the rice blast disease caused by the fungus Magnaporthe oryzae. Several major blast resistance genes and QTLs associated with blast resistance have been described and mostly identified in indica rice varieties. In this work, we report the obtention of a blast-resistant rice breeding line derived from crosses between the resistant indica variety CT13432 and the japonica elite cultivar JSendra (highly susceptible to blast). The breeding line, named COPSEMAR9, was found to exhibit resistance to leaf blast and panicle blast, as demonstrated by disease assays under controlled and field conditions. Furthermore, a high-quality genome sequence of the blast-resistant breeding line was obtained using a strategy that combines short-read sequencing (Illumina sequencing) and long-read sequencing (Pacbio sequencing). The use of a whole-genome approach allowed the fine mapping of DNA regions of indica and japonica origin present in the COPSEMAR9 genome and the identification of parental gene regions potentially contributing to blast resistance in the breeding line. Rice blast resistance genes (including Pi33 derived from the resistant parent) and defense-related genes in the genome of COPSEMAR9 were identified. Whole-genome analyses also revealed the presence of microRNAs (miRNAs) with a known function in the rice response to M. oryzae infection in COPSEMAR9, which might also contribute to its phenotype of blast resistance. From this study, the genomic information and analysis methods provide valuable knowledge that will be useful in breeding programs for blast resistance in japonica rice cultivars. 2024-05-23T11:08:27Z 2024-05-23T11:08:27Z 2023 article publishedVersion Escolà, G., González-Miguel, V. M., Campo, S., Catala-Forner, M., Domingo, C., Marqués, L., & San Segundo, B. (2023). Development and Genome-Wide Analysis of a Blast-Resistant japonica Rice Variety. Plants, 12(20), 3536. 2223-7747 https://hdl.handle.net/20.500.11939/8915 10.3390/plants12203536 https://www.mdpi.com/2223-7747/12/20/3536 en This researchwas supported by Projects RTI2018-101275-B-I00 and PID2021-128825OB-I00 funded byMCIN/AEI/10.13039/501100011033 and by “ERDF A way ofmaking Europe” to B.SS, and PID2019- 104099RR-I00 to C.D. We acknowledge financial support from the MCIN/AEI/10.13039/501100011033 through the “Severo Ochoa Programme for Centres of Excellence in R&D” (SEV-2015-0533 and CEX2019- 000902-S) and the CERCA Programe/“Generalitat de Catalunya”. We also thank support fromthe CSIC Open Access Publication Support Initiative through its Unit of Information Resources for Research (URICI). G.E.was the recipient of Grant PEJ2018-002245-P funded byMCIN/AEI/10.13039/501100011033 and by “ESF Investing in your future”. Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ openAccess MDPI electronico
spellingShingle Genome mapping
Japonica
Magnaporthe oryzae
MicroRNA
Resistance
F30 Plant genetics and breeding
Breeding
Defense response
Oryza sativa
Escolà, Glòria
González-Miguel, Víctor M.
Campo, Sonia
Catala-Forner, Mar
Domingo, Concha
Marqués, Luis
San Segundo, Blanca
Development and Genome-Wide Analysis of a Blast-Resistant japonica Rice Variety
title Development and Genome-Wide Analysis of a Blast-Resistant japonica Rice Variety
title_full Development and Genome-Wide Analysis of a Blast-Resistant japonica Rice Variety
title_fullStr Development and Genome-Wide Analysis of a Blast-Resistant japonica Rice Variety
title_full_unstemmed Development and Genome-Wide Analysis of a Blast-Resistant japonica Rice Variety
title_short Development and Genome-Wide Analysis of a Blast-Resistant japonica Rice Variety
title_sort development and genome wide analysis of a blast resistant japonica rice variety
topic Genome mapping
Japonica
Magnaporthe oryzae
MicroRNA
Resistance
F30 Plant genetics and breeding
Breeding
Defense response
Oryza sativa
url https://hdl.handle.net/20.500.11939/8915
https://www.mdpi.com/2223-7747/12/20/3536
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