Complete circularized genome resources of seven strains of Xylella fastidiosa subsp. fastidiosa using hybrid assembly reveals unknown plasmids

Xylella fastidiosa (Xf) is a vascular plant pathogenic bacterium native to the Americas that is causing significant epidemics and economic losses in olive and almonds in Europe, where it is a quarantine pathogen. Since its first detection in 2013 in Italy, mandatory surveys across Europe revealed th...

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Autores principales: Velasco-Amo, María P., Arias-Giraldo, Luis F., Román-Écija, Miguel, de-la-Fuente, Leonardo, Marco-Noales, Ester, Moralejo, Eduardo, Navas-Cortés, Juan A., Landa, Blanca B.
Formato: article
Lenguaje:Inglés
Publicado: American Phytopathological Society (APS) 2023
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Acceso en línea:https://hdl.handle.net/20.500.11939/8665
https://apsjournals.apsnet.org/doi/10.1094/PHYTO-10-22-0396-A
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author Velasco-Amo, María P.
Arias-Giraldo, Luis F.
Román-Écija, Miguel
de-la-Fuente, Leonardo
Marco-Noales, Ester
Moralejo, Eduardo
Navas-Cortés, Juan A.
Landa, Blanca B.
author_browse Arias-Giraldo, Luis F.
Landa, Blanca B.
Marco-Noales, Ester
Moralejo, Eduardo
Navas-Cortés, Juan A.
Román-Écija, Miguel
Velasco-Amo, María P.
de-la-Fuente, Leonardo
author_facet Velasco-Amo, María P.
Arias-Giraldo, Luis F.
Román-Écija, Miguel
de-la-Fuente, Leonardo
Marco-Noales, Ester
Moralejo, Eduardo
Navas-Cortés, Juan A.
Landa, Blanca B.
author_sort Velasco-Amo, María P.
collection ReDivia
description Xylella fastidiosa (Xf) is a vascular plant pathogenic bacterium native to the Americas that is causing significant epidemics and economic losses in olive and almonds in Europe, where it is a quarantine pathogen. Since its first detection in 2013 in Italy, mandatory surveys across Europe revealed the presence of the bacterium also in France, Spain, and Portugal. Combining ONT and Illumina sequencing data, we assembled high-quality complete genomes of seven Xf subsp. fastidiosa strains isolated from different plants in Spain, the USA, and Mexico. Comparative genomic analyses discovered differences in plasmid content among strains, including plasmids that had been overlooked previously when using Illumina sequencing platform alone. Interestingly, in strain CFBP8073, intercepted in France from plants imported from Mexico, three plasmids were identified, including two (plasmid pXF-P1.CFBP8073 and pXF-P2.CFBP8073) not previously described in X. fastidiosa, and one (pXF5823.CFBP8073) almost identical to a plasmid described in a Xf strain from citrus. Plasmids found in the Spanish strains here were similar to those described previously in other strains from the same subspecies and ST1 isolated in the Balearic Islands and the USA. The genome resources from this work will assist in further studies on the role of plasmids in the epidemiology, ecology, and evolution of this plant pathogen.
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spelling ReDivia86652025-04-25T14:49:15Z Complete circularized genome resources of seven strains of Xylella fastidiosa subsp. fastidiosa using hybrid assembly reveals unknown plasmids Velasco-Amo, María P. Arias-Giraldo, Luis F. Román-Écija, Miguel de-la-Fuente, Leonardo Marco-Noales, Ester Moralejo, Eduardo Navas-Cortés, Juan A. Landa, Blanca B. Bacterial pathogens Microbe-genome Sequencing Bioinformatics Ecology Xylella fastidiosa Plasmids Plant pathology Xylella fastidiosa (Xf) is a vascular plant pathogenic bacterium native to the Americas that is causing significant epidemics and economic losses in olive and almonds in Europe, where it is a quarantine pathogen. Since its first detection in 2013 in Italy, mandatory surveys across Europe revealed the presence of the bacterium also in France, Spain, and Portugal. Combining ONT and Illumina sequencing data, we assembled high-quality complete genomes of seven Xf subsp. fastidiosa strains isolated from different plants in Spain, the USA, and Mexico. Comparative genomic analyses discovered differences in plasmid content among strains, including plasmids that had been overlooked previously when using Illumina sequencing platform alone. Interestingly, in strain CFBP8073, intercepted in France from plants imported from Mexico, three plasmids were identified, including two (plasmid pXF-P1.CFBP8073 and pXF-P2.CFBP8073) not previously described in X. fastidiosa, and one (pXF5823.CFBP8073) almost identical to a plasmid described in a Xf strain from citrus. Plasmids found in the Spanish strains here were similar to those described previously in other strains from the same subspecies and ST1 isolated in the Balearic Islands and the USA. The genome resources from this work will assist in further studies on the role of plasmids in the epidemiology, ecology, and evolution of this plant pathogen. 2023-06-23T12:07:07Z 2023-06-23T12:07:07Z 2023 article publishedVersion Velasco-Amo, M. P., Arias-Giraldo, L. F., Román-Écija, M., Fuente, L. D. L., Marco-Noales, E., Moralejo, E., ... & Landa, B. B. (2023). Complete circularized genome resources of seven strains of Xylella fastidiosa subsp. fastidiosa using hybrid assembly reveals unknown plasmids. Phytopathology®, 113(6), 1128-1132. 0031-949X 1943-7684 (e-ISSN) https://hdl.handle.net/20.500.11939/8665 10.1094/phyto-10-22-0396-a https://apsjournals.apsnet.org/doi/10.1094/PHYTO-10-22-0396-A en Support was provided by the HORIZON-CL6-2021-FARM2FORK-01 project BeXyl (Beyond Xylella, Integrated Management Strategies for Mitigating Xylella fastidiosa Impact in Europe; grant 101060593); the project ERTA2017-00004-C06-02 (Desarrollo de estrategias de erradicación, contención y control de X. fastidiosa en España) from the ‘Programa Estatal de I+D+I Orientada a los Retos de la Sociedad’ of the Spanish Government (AEI-INIA Spain); the Spanish Olive Oil Interprofessional; and the Thematic Interdisciplinary Platform on X. fastidiosa, PTI Sol-Xyl, from Consejo Superior de Investigaciones Científicas. Financial support from the Spanish Ministry of Agriculture and Fisheries to the Institute for Sustainable Agriculture is also acknowledged. L. De La Fuente was a recipient of a research fellowship awarded by the Organization for Economic Cooperation and Development, Cooperative Research Programme, during the writing of this manuscript. M. P. Velasco-Amo was a recipient of a contract financed by the Consejo Superior de Investigaciones Científicas Intramural Project 201840E111. Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ openAccess American Phytopathological Society (APS) electronico
spellingShingle Bacterial pathogens
Microbe-genome Sequencing
Bioinformatics
Ecology
Xylella fastidiosa
Plasmids
Plant pathology
Velasco-Amo, María P.
Arias-Giraldo, Luis F.
Román-Écija, Miguel
de-la-Fuente, Leonardo
Marco-Noales, Ester
Moralejo, Eduardo
Navas-Cortés, Juan A.
Landa, Blanca B.
Complete circularized genome resources of seven strains of Xylella fastidiosa subsp. fastidiosa using hybrid assembly reveals unknown plasmids
title Complete circularized genome resources of seven strains of Xylella fastidiosa subsp. fastidiosa using hybrid assembly reveals unknown plasmids
title_full Complete circularized genome resources of seven strains of Xylella fastidiosa subsp. fastidiosa using hybrid assembly reveals unknown plasmids
title_fullStr Complete circularized genome resources of seven strains of Xylella fastidiosa subsp. fastidiosa using hybrid assembly reveals unknown plasmids
title_full_unstemmed Complete circularized genome resources of seven strains of Xylella fastidiosa subsp. fastidiosa using hybrid assembly reveals unknown plasmids
title_short Complete circularized genome resources of seven strains of Xylella fastidiosa subsp. fastidiosa using hybrid assembly reveals unknown plasmids
title_sort complete circularized genome resources of seven strains of xylella fastidiosa subsp fastidiosa using hybrid assembly reveals unknown plasmids
topic Bacterial pathogens
Microbe-genome Sequencing
Bioinformatics
Ecology
Xylella fastidiosa
Plasmids
Plant pathology
url https://hdl.handle.net/20.500.11939/8665
https://apsjournals.apsnet.org/doi/10.1094/PHYTO-10-22-0396-A
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