From the smallest to the largest subcellular plant pathogen: Citrus tristeza virus and its unique p23 protein

Knowledge on diseases caused by Citrus tristeza virus (CTV) has greatly increased in last decades after their etiology was demonstrated in the past seventies. Professor Ricardo Flores substantially contributed to these advances in topics like: I) improvement of virus purification to obtain biologica...

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Autores principales: Moreno, Pedro, Lopez, Carmelo, Ruiz-Ruiz, Susana, Pena, Leandro, Guerri, José
Formato: Artículo
Lenguaje:Inglés
Publicado: Elsevier 2022
Materias:
Acceso en línea:http://hdl.handle.net/20.500.11939/8013
https://www.sciencedirect.com/science/article/pii/S0168170222000831?via%3Dihub
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author Moreno, Pedro
Lopez, Carmelo
Ruiz-Ruiz, Susana
Pena, Leandro
Guerri, José
author_browse Guerri, José
Lopez, Carmelo
Moreno, Pedro
Pena, Leandro
Ruiz-Ruiz, Susana
author_facet Moreno, Pedro
Lopez, Carmelo
Ruiz-Ruiz, Susana
Pena, Leandro
Guerri, José
author_sort Moreno, Pedro
collection ReDivia
description Knowledge on diseases caused by Citrus tristeza virus (CTV) has greatly increased in last decades after their etiology was demonstrated in the past seventies. Professor Ricardo Flores substantially contributed to these advances in topics like: I) improvement of virus purification to obtain biologically active virions, II) sequencing mild CTV isolates for genetic comparisons with sequences of moderate or severe isolates and genetic engineering, III) analysis of genetic variation of both CTV genomic RNA ends and features of the highly variable 5′ end that allow accommodating this variation within a conserved secondary structure, IV) studies on the structure, subcellular localization and biological functions of the CTV-unique p23 protein, and v) potential use of p23 and other 3′ -proximal regions of the CTV genome to develop transgenic citrus resistant to the virus. Here we review his main achievements on these topics and how they contributed to deeper understanding of CTV biology and to new potential measures for disease control.
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spelling ReDivia80132025-04-25T14:48:40Z From the smallest to the largest subcellular plant pathogen: Citrus tristeza virus and its unique p23 protein Moreno, Pedro Lopez, Carmelo Ruiz-Ruiz, Susana Pena, Leandro Guerri, José CTV pathogenicity CTV resistance p23 protein p23 subcellular localization Virus-host interactions p23-transgenic citrus H20 Plant diseases F60 Plant physiology and biochemistry Knowledge on diseases caused by Citrus tristeza virus (CTV) has greatly increased in last decades after their etiology was demonstrated in the past seventies. Professor Ricardo Flores substantially contributed to these advances in topics like: I) improvement of virus purification to obtain biologically active virions, II) sequencing mild CTV isolates for genetic comparisons with sequences of moderate or severe isolates and genetic engineering, III) analysis of genetic variation of both CTV genomic RNA ends and features of the highly variable 5′ end that allow accommodating this variation within a conserved secondary structure, IV) studies on the structure, subcellular localization and biological functions of the CTV-unique p23 protein, and v) potential use of p23 and other 3′ -proximal regions of the CTV genome to develop transgenic citrus resistant to the virus. Here we review his main achievements on these topics and how they contributed to deeper understanding of CTV biology and to new potential measures for disease control. 2022-03-30T15:23:50Z 2022-03-30T15:23:50Z 2022 article publishedVersion Moreno, P., Lopez, C., Ruiz-Ruiz, S., Pena, L. & Guerri, J. (2022). From the smallest to the largest subcellular plant pathogen: Citrus tristeza virus and its unique p23 protein. Virus Research, 314, 198755. 0168-1702 http://hdl.handle.net/20.500.11939/8013 10.1016/j.virusres.2022.198755 https://www.sciencedirect.com/science/article/pii/S0168170222000831?via%3Dihub en Atribución-NoComercial-SinDerivadas 3.0 España http://creativecommons.org/licenses/by-nc-nd/3.0/es/ openAccess Elsevier electronico
spellingShingle CTV pathogenicity
CTV resistance
p23 protein
p23 subcellular localization
Virus-host interactions
p23-transgenic citrus
H20 Plant diseases
F60 Plant physiology and biochemistry
Moreno, Pedro
Lopez, Carmelo
Ruiz-Ruiz, Susana
Pena, Leandro
Guerri, José
From the smallest to the largest subcellular plant pathogen: Citrus tristeza virus and its unique p23 protein
title From the smallest to the largest subcellular plant pathogen: Citrus tristeza virus and its unique p23 protein
title_full From the smallest to the largest subcellular plant pathogen: Citrus tristeza virus and its unique p23 protein
title_fullStr From the smallest to the largest subcellular plant pathogen: Citrus tristeza virus and its unique p23 protein
title_full_unstemmed From the smallest to the largest subcellular plant pathogen: Citrus tristeza virus and its unique p23 protein
title_short From the smallest to the largest subcellular plant pathogen: Citrus tristeza virus and its unique p23 protein
title_sort from the smallest to the largest subcellular plant pathogen citrus tristeza virus and its unique p23 protein
topic CTV pathogenicity
CTV resistance
p23 protein
p23 subcellular localization
Virus-host interactions
p23-transgenic citrus
H20 Plant diseases
F60 Plant physiology and biochemistry
url http://hdl.handle.net/20.500.11939/8013
https://www.sciencedirect.com/science/article/pii/S0168170222000831?via%3Dihub
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