Comparative Genomic and Phenotypic Characterization of Pathogenic and Non-Pathogenic Strains of Xanthomonas arboricola Reveals Insights into the Infection Process of Bacterial Spot Disease of Stone Fruits

Xanthomonas arboricola pv. pruni is the causal agent of bacterial spot disease of stone fruits, a quarantinable pathogen in several areas worldwide, including the European Union. In order to develop efficient control methods for this disease, it is necessary to improve the understanding of the key d...

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Autores principales: Garita-Cambronero, Jerson, Palacio-Bielsa, Ana, López, María M., Cubero, Jaime
Formato: Artículo
Lenguaje:Inglés
Publicado: PLOS 2020
Materias:
Acceso en línea:http://hdl.handle.net/20.500.11939/6743
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161977
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author Garita-Cambronero, Jerson
Palacio-Bielsa, Ana
López, María M.
Cubero, Jaime
author_browse Cubero, Jaime
Garita-Cambronero, Jerson
López, María M.
Palacio-Bielsa, Ana
author_facet Garita-Cambronero, Jerson
Palacio-Bielsa, Ana
López, María M.
Cubero, Jaime
author_sort Garita-Cambronero, Jerson
collection ReDivia
description Xanthomonas arboricola pv. pruni is the causal agent of bacterial spot disease of stone fruits, a quarantinable pathogen in several areas worldwide, including the European Union. In order to develop efficient control methods for this disease, it is necessary to improve the understanding of the key determinants associated with host restriction, colonization and the development of pathogenesis. After an initial characterization, by multilocus sequence analysis, of 15 strains of X. arboricola isolated from Prunus, one strain did not group into the pathovar pruni or into other pathovars of this species and therefore it was identified and defined as a X. arboricola pv. pruni look-a-like. This non-pathogenic strain and two typical strains of X. arboricola pv. pruni were selected for a whole genome and phenotype comparative analysis in features associated with the pathogenesis process in Xanthomonas. Comparative analysis among these bacterial strains isolated from Prunus spp. and the inclusion of 15 publicly available genome sequences from other pathogenic and non-pathogenic strains of X. arboricola revealed variations in the phenotype associated with variations in the profiles of TonB-dependent transporters, sensors of the two-component regulatory system, methyl accepting chemotaxis proteins, components of the flagella and the type IV pilus, as well as in the repertoire of cell-wall degrading enzymes and the components of the type III secretion system and related effectors. These variations provide a global overview of those mechanisms that could be associated with the development of bacterial spot disease. Additionally, it pointed out some features that might influence the host specificity and the variable virulence observed in X. arboricola.
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spelling ReDivia67432025-04-25T14:47:46Z Comparative Genomic and Phenotypic Characterization of Pathogenic and Non-Pathogenic Strains of Xanthomonas arboricola Reveals Insights into the Infection Process of Bacterial Spot Disease of Stone Fruits Garita-Cambronero, Jerson Palacio-Bielsa, Ana López, María M. Cubero, Jaime Genomic Characterization Xanthomonas arboricola Bacterial spot disease H20 Plant diseases Xanthomonas arboricola pv. pruni is the causal agent of bacterial spot disease of stone fruits, a quarantinable pathogen in several areas worldwide, including the European Union. In order to develop efficient control methods for this disease, it is necessary to improve the understanding of the key determinants associated with host restriction, colonization and the development of pathogenesis. After an initial characterization, by multilocus sequence analysis, of 15 strains of X. arboricola isolated from Prunus, one strain did not group into the pathovar pruni or into other pathovars of this species and therefore it was identified and defined as a X. arboricola pv. pruni look-a-like. This non-pathogenic strain and two typical strains of X. arboricola pv. pruni were selected for a whole genome and phenotype comparative analysis in features associated with the pathogenesis process in Xanthomonas. Comparative analysis among these bacterial strains isolated from Prunus spp. and the inclusion of 15 publicly available genome sequences from other pathogenic and non-pathogenic strains of X. arboricola revealed variations in the phenotype associated with variations in the profiles of TonB-dependent transporters, sensors of the two-component regulatory system, methyl accepting chemotaxis proteins, components of the flagella and the type IV pilus, as well as in the repertoire of cell-wall degrading enzymes and the components of the type III secretion system and related effectors. These variations provide a global overview of those mechanisms that could be associated with the development of bacterial spot disease. Additionally, it pointed out some features that might influence the host specificity and the variable virulence observed in X. arboricola. 2020-11-11T09:17:41Z 2020-11-11T09:17:41Z 2016 article publishedVersion Garita-Cambronero, J., Palacio-Bielsa, A., López, M. M., & Cubero, J. (2016). Comparative genomic and phenotypic characterization of pathogenic and non-pathogenic strains of Xanthomonas arboricola reveals insights into the infection process of bacterial spot disease of stone fruits. PloS one, 11(8), e0161977. 1932-6203 (eISSN) http://hdl.handle.net/20.500.11939/6743 10.1371/journal.pone.0161977 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161977 en Atribución-NoComercial-SinDerivadas 3.0 España http://creativecommons.org/licenses/by-nc-nd/3.0/es/ openAccess PLOS electronico
spellingShingle Genomic Characterization
Xanthomonas arboricola
Bacterial spot disease
H20 Plant diseases
Garita-Cambronero, Jerson
Palacio-Bielsa, Ana
López, María M.
Cubero, Jaime
Comparative Genomic and Phenotypic Characterization of Pathogenic and Non-Pathogenic Strains of Xanthomonas arboricola Reveals Insights into the Infection Process of Bacterial Spot Disease of Stone Fruits
title Comparative Genomic and Phenotypic Characterization of Pathogenic and Non-Pathogenic Strains of Xanthomonas arboricola Reveals Insights into the Infection Process of Bacterial Spot Disease of Stone Fruits
title_full Comparative Genomic and Phenotypic Characterization of Pathogenic and Non-Pathogenic Strains of Xanthomonas arboricola Reveals Insights into the Infection Process of Bacterial Spot Disease of Stone Fruits
title_fullStr Comparative Genomic and Phenotypic Characterization of Pathogenic and Non-Pathogenic Strains of Xanthomonas arboricola Reveals Insights into the Infection Process of Bacterial Spot Disease of Stone Fruits
title_full_unstemmed Comparative Genomic and Phenotypic Characterization of Pathogenic and Non-Pathogenic Strains of Xanthomonas arboricola Reveals Insights into the Infection Process of Bacterial Spot Disease of Stone Fruits
title_short Comparative Genomic and Phenotypic Characterization of Pathogenic and Non-Pathogenic Strains of Xanthomonas arboricola Reveals Insights into the Infection Process of Bacterial Spot Disease of Stone Fruits
title_sort comparative genomic and phenotypic characterization of pathogenic and non pathogenic strains of xanthomonas arboricola reveals insights into the infection process of bacterial spot disease of stone fruits
topic Genomic Characterization
Xanthomonas arboricola
Bacterial spot disease
H20 Plant diseases
url http://hdl.handle.net/20.500.11939/6743
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161977
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