The dynamic of antibiotic resistance in commensal Escherichia coli throughout the growing period in broiler chickens: fast-growing vs. slow-growing breeds
Antimicrobial resistance (AMR) is an important threat to public health worldwide. Furthermore, different studies have demonstrated a close association between antibiotic use in animal production and AMR in humans. It is well known that it is necessary to reduce antibiotic administration in farms by...
| Main Authors: | , , , , , |
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| Format: | article |
| Language: | Inglés |
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Elsevier
2020
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| Online Access: | http://hdl.handle.net/20.500.11939/6646 https://www.sciencedirect.com/science/article/pii/S0032579119578105?via%3Dihub |
| _version_ | 1855032464078012416 |
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| author | Montoro-Dasí, Laura Villagrá, Arantxa Sevilla-Navarro, Sandra Pérez-Gracia, María T. Vega, Santiago Marín, Clara |
| author_browse | Marín, Clara Montoro-Dasí, Laura Pérez-Gracia, María T. Sevilla-Navarro, Sandra Vega, Santiago Villagrá, Arantxa |
| author_facet | Montoro-Dasí, Laura Villagrá, Arantxa Sevilla-Navarro, Sandra Pérez-Gracia, María T. Vega, Santiago Marín, Clara |
| author_sort | Montoro-Dasí, Laura |
| collection | ReDivia |
| description | Antimicrobial resistance (AMR) is an important threat to public health worldwide. Furthermore, different studies have demonstrated a close association between antibiotic use in animal production and AMR in humans. It is well known that it is necessary to reduce antibiotic administration in farms by finding effective alternative treatments, using more resistant breeds and improving animal welfare. However, to be able to assess the alternatives proposed, it is essential to study the epidemiology of AMR under production conditions. Hence, the aim of this study was to investigate the AMR dynamic in 2 genetic poultry breeds during the growing period. The study was performed in 2 experimental poultry houses to simulate real production conditions, and no antibiotics were administered during the growing period. In addition, 2 poultry breeds were used, fast-growing and slow-growing. To evaluate AMR evolution, Escherichia coli was selected as indicator bacterium. To this end, animals from each experimental group were sampled at different times: on day of arrival, at mid-period, and at slaughter day. In the laboratory, cecal content was removed and inoculated in selective media. Then, biochemical tests were performed to confirm E. coli. Finally, antibiotic susceptibility was assessed according to Decision 2013/653. At the onset of the cycle, significant differences were observed between breeds, as the E. coli strains isolated from fast-growing 1-day-old-chicks showed higher AMR rates. However, at the end of the period, no significant differences were found between breeds and their presence of resistant bacteria (above 95%). Therefore, although no antibiotics were administered during the growing period, a high level of AMR at slaughter day was demonstrated. Further studies are necessary to determine the main risk factors that increase the level of AMR throughout the productive cycle in broiler chickens. In conclusion, it is important to highlight that although it is crucial to control both antibiotic use and animal welfare during the growing period, measures should be taken at all levels of the production chain. |
| format | article |
| id | ReDivia6646 |
| institution | Instituto Valenciano de Investigaciones Agrarias (IVIA) |
| language | Inglés |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | ReDivia66462025-04-25T14:47:31Z The dynamic of antibiotic resistance in commensal Escherichia coli throughout the growing period in broiler chickens: fast-growing vs. slow-growing breeds Montoro-Dasí, Laura Villagrá, Arantxa Sevilla-Navarro, Sandra Pérez-Gracia, María T. Vega, Santiago Marín, Clara Multidrug-resistance L73 Animal diseases Antimicrobial resistance Broilers Growing period Escherichia coli Antimicrobial resistance (AMR) is an important threat to public health worldwide. Furthermore, different studies have demonstrated a close association between antibiotic use in animal production and AMR in humans. It is well known that it is necessary to reduce antibiotic administration in farms by finding effective alternative treatments, using more resistant breeds and improving animal welfare. However, to be able to assess the alternatives proposed, it is essential to study the epidemiology of AMR under production conditions. Hence, the aim of this study was to investigate the AMR dynamic in 2 genetic poultry breeds during the growing period. The study was performed in 2 experimental poultry houses to simulate real production conditions, and no antibiotics were administered during the growing period. In addition, 2 poultry breeds were used, fast-growing and slow-growing. To evaluate AMR evolution, Escherichia coli was selected as indicator bacterium. To this end, animals from each experimental group were sampled at different times: on day of arrival, at mid-period, and at slaughter day. In the laboratory, cecal content was removed and inoculated in selective media. Then, biochemical tests were performed to confirm E. coli. Finally, antibiotic susceptibility was assessed according to Decision 2013/653. At the onset of the cycle, significant differences were observed between breeds, as the E. coli strains isolated from fast-growing 1-day-old-chicks showed higher AMR rates. However, at the end of the period, no significant differences were found between breeds and their presence of resistant bacteria (above 95%). Therefore, although no antibiotics were administered during the growing period, a high level of AMR at slaughter day was demonstrated. Further studies are necessary to determine the main risk factors that increase the level of AMR throughout the productive cycle in broiler chickens. In conclusion, it is important to highlight that although it is crucial to control both antibiotic use and animal welfare during the growing period, measures should be taken at all levels of the production chain. 2020-10-14T08:44:35Z 2020-10-14T08:44:35Z 2020 article publishedVersion Montoro-Dasi, L., Villagra, A., Sevilla-Navarro, S., Pérez-Gracia, M. T., Vega, S. & Marin, C. (2020). The dynamic of antibiotic resistance in commensal Escherichia coli throughout the growing period in broiler chickens: fast-growing vs. slow-growing breeds. Poultry Science, 99(3), 1591-1597. 0032-5791 http://hdl.handle.net/20.500.11939/6646 10.1016/j.psj.2019.10.080 https://www.sciencedirect.com/science/article/pii/S0032579119578105?via%3Dihub en Atribución-NoComercial-SinDerivadas 3.0 España http://creativecommons.org/licenses/by-nc-nd/3.0/es/ openAccess Elsevier electronico |
| spellingShingle | Multidrug-resistance L73 Animal diseases Antimicrobial resistance Broilers Growing period Escherichia coli Montoro-Dasí, Laura Villagrá, Arantxa Sevilla-Navarro, Sandra Pérez-Gracia, María T. Vega, Santiago Marín, Clara The dynamic of antibiotic resistance in commensal Escherichia coli throughout the growing period in broiler chickens: fast-growing vs. slow-growing breeds |
| title | The dynamic of antibiotic resistance in commensal Escherichia coli throughout the growing period in broiler chickens: fast-growing vs. slow-growing breeds |
| title_full | The dynamic of antibiotic resistance in commensal Escherichia coli throughout the growing period in broiler chickens: fast-growing vs. slow-growing breeds |
| title_fullStr | The dynamic of antibiotic resistance in commensal Escherichia coli throughout the growing period in broiler chickens: fast-growing vs. slow-growing breeds |
| title_full_unstemmed | The dynamic of antibiotic resistance in commensal Escherichia coli throughout the growing period in broiler chickens: fast-growing vs. slow-growing breeds |
| title_short | The dynamic of antibiotic resistance in commensal Escherichia coli throughout the growing period in broiler chickens: fast-growing vs. slow-growing breeds |
| title_sort | dynamic of antibiotic resistance in commensal escherichia coli throughout the growing period in broiler chickens fast growing vs slow growing breeds |
| topic | Multidrug-resistance L73 Animal diseases Antimicrobial resistance Broilers Growing period Escherichia coli |
| url | http://hdl.handle.net/20.500.11939/6646 https://www.sciencedirect.com/science/article/pii/S0032579119578105?via%3Dihub |
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