Molecular Characterization of the Complete Coding Sequence of Olive Leaf Yellowing-Associated Virus

Genome organization and phylogenetic relationships of olive leaf yellowing-associated virus (OLYaV) with other members of the Closteroviridae family were determined. The complete coding sequence of OLYaV was obtained by high throughput sequencing of total RNA from a 35-year-old olive tree (cv. Zarza...

Full description

Bibliographic Details
Main Authors: Ruiz-García, Ana B., Candresse, Thierry, Canales, Celia, Morán, Félix, Machado de Oliveira, Carlos, Bertolini, Edson, Olmos, Antonio
Format: publishedVersion
Language:Inglés
Published: MDPI 2020
Subjects:
Online Access:http://hdl.handle.net/20.500.11939/6614
https://www.mdpi.com/2223-7747/9/10/1272
_version_ 1855032458792140800
author Ruiz-García, Ana B.
Candresse, Thierry
Canales, Celia
Morán, Félix
Machado de Oliveira, Carlos
Bertolini, Edson
Olmos, Antonio
author_browse Bertolini, Edson
Canales, Celia
Candresse, Thierry
Machado de Oliveira, Carlos
Morán, Félix
Olmos, Antonio
Ruiz-García, Ana B.
author_facet Ruiz-García, Ana B.
Candresse, Thierry
Canales, Celia
Morán, Félix
Machado de Oliveira, Carlos
Bertolini, Edson
Olmos, Antonio
author_sort Ruiz-García, Ana B.
collection ReDivia
description Genome organization and phylogenetic relationships of olive leaf yellowing-associated virus (OLYaV) with other members of the Closteroviridae family were determined. The complete coding sequence of OLYaV was obtained by high throughput sequencing of total RNA from a 35-year-old olive tree (cv. Zarzaleña) from Brazil, showing olive leaf yellowing disease and deformations in the wood. This represents the first report of OLYaV in this country. A genomic sequence of 16,700 nt containing 11 open reading frames (ORFs) was recovered, representing the complete virus coding capacity. The knowledge of the nucleotide sequence of the genome including the gene that codes the coat protein will facilitate the development of diagnostic tests, which are limited so far to PCR-based methods targeting the HSP70h gene. Interestingly, a thaumatin-like protein (ORF2), previously reported in other unassigned viruses in the Closteroviridae family, persimmon virus B and actidinia virus 1, was identified in the OLYaV genome. Phylogenetic analysis of shared proteins (ORF1a, ORF1b, HSP70h, HSP90h and CP) with all members of the Closteroviridae family provides new insight into the taxonomic position of these three closteroviruses and suggests they could represent a new genus in the family.
format publishedVersion
id ReDivia6614
institution Instituto Valenciano de Investigaciones Agrarias (IVIA)
language Inglés
publishDate 2020
publishDateRange 2020
publishDateSort 2020
publisher MDPI
publisherStr MDPI
record_format dspace
spelling ReDivia66142025-04-25T14:47:27Z Molecular Characterization of the Complete Coding Sequence of Olive Leaf Yellowing-Associated Virus Ruiz-García, Ana B. Candresse, Thierry Canales, Celia Morán, Félix Machado de Oliveira, Carlos Bertolini, Edson Olmos, Antonio Closteroviridae thaumatin-like protein genome high-throughput sequencing NGS Olive leaf yellowing-associated virus H20 Plant diseases Olives Genome organization and phylogenetic relationships of olive leaf yellowing-associated virus (OLYaV) with other members of the Closteroviridae family were determined. The complete coding sequence of OLYaV was obtained by high throughput sequencing of total RNA from a 35-year-old olive tree (cv. Zarzaleña) from Brazil, showing olive leaf yellowing disease and deformations in the wood. This represents the first report of OLYaV in this country. A genomic sequence of 16,700 nt containing 11 open reading frames (ORFs) was recovered, representing the complete virus coding capacity. The knowledge of the nucleotide sequence of the genome including the gene that codes the coat protein will facilitate the development of diagnostic tests, which are limited so far to PCR-based methods targeting the HSP70h gene. Interestingly, a thaumatin-like protein (ORF2), previously reported in other unassigned viruses in the Closteroviridae family, persimmon virus B and actidinia virus 1, was identified in the OLYaV genome. Phylogenetic analysis of shared proteins (ORF1a, ORF1b, HSP70h, HSP90h and CP) with all members of the Closteroviridae family provides new insight into the taxonomic position of these three closteroviruses and suggests they could represent a new genus in the family. 2020-09-30T08:10:40Z 2020-09-30T08:10:40Z 2020 publishedVersion Ruiz-García, A.B.; Candresse, T.; Canales, C.; Morán, F.; Machado de Oliveira, C.; Bertolini, E.; Olmos, A. (2020). Molecular Characterization of the Complete Coding Sequence of Olive Leaf Yellowing-Associated Virus. Plants 2020, 9 (10), 1272. 2223-7747 http://hdl.handle.net/20.500.11939/6614 10.3390/plants9101272 https://www.mdpi.com/2223-7747/9/10/1272 en info:eu-repo/grantAgreement/ERDF/POCV 2014-2020/51912 IVIA 51912 Atribución-NoComercial-SinDerivadas 3.0 España http://creativecommons.org/licenses/by-nc-nd/3.0/es/ openAccess MDPI electronico
spellingShingle Closteroviridae
thaumatin-like protein
genome
high-throughput sequencing
NGS
Olive leaf yellowing-associated virus
H20 Plant diseases
Olives
Ruiz-García, Ana B.
Candresse, Thierry
Canales, Celia
Morán, Félix
Machado de Oliveira, Carlos
Bertolini, Edson
Olmos, Antonio
Molecular Characterization of the Complete Coding Sequence of Olive Leaf Yellowing-Associated Virus
title Molecular Characterization of the Complete Coding Sequence of Olive Leaf Yellowing-Associated Virus
title_full Molecular Characterization of the Complete Coding Sequence of Olive Leaf Yellowing-Associated Virus
title_fullStr Molecular Characterization of the Complete Coding Sequence of Olive Leaf Yellowing-Associated Virus
title_full_unstemmed Molecular Characterization of the Complete Coding Sequence of Olive Leaf Yellowing-Associated Virus
title_short Molecular Characterization of the Complete Coding Sequence of Olive Leaf Yellowing-Associated Virus
title_sort molecular characterization of the complete coding sequence of olive leaf yellowing associated virus
topic Closteroviridae
thaumatin-like protein
genome
high-throughput sequencing
NGS
Olive leaf yellowing-associated virus
H20 Plant diseases
Olives
url http://hdl.handle.net/20.500.11939/6614
https://www.mdpi.com/2223-7747/9/10/1272
work_keys_str_mv AT ruizgarciaanab molecularcharacterizationofthecompletecodingsequenceofoliveleafyellowingassociatedvirus
AT candressethierry molecularcharacterizationofthecompletecodingsequenceofoliveleafyellowingassociatedvirus
AT canalescelia molecularcharacterizationofthecompletecodingsequenceofoliveleafyellowingassociatedvirus
AT moranfelix molecularcharacterizationofthecompletecodingsequenceofoliveleafyellowingassociatedvirus
AT machadodeoliveiracarlos molecularcharacterizationofthecompletecodingsequenceofoliveleafyellowingassociatedvirus
AT bertoliniedson molecularcharacterizationofthecompletecodingsequenceofoliveleafyellowingassociatedvirus
AT olmosantonio molecularcharacterizationofthecompletecodingsequenceofoliveleafyellowingassociatedvirus