Synthesis of benzopyran derivatives as PPARα and/or PPARγ activators
We describe the synthesis of 26 compounds, small polycerasoidol analogs, that are Lipinski’s rule-of-five compliant. In order to confirm key structural features to activate PPARα and/or PPARγ, we have adopted structural modifications in the following parts: (i) the benzopyran core (hydrophobic nucle...
| Autores principales: | , , , , , , , , , , , , , , |
|---|---|
| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
2020
|
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.11939/6461 https://www.sciencedirect.com/science/article/pii/S0968089619316505 |
Ejemplares similares: Synthesis of benzopyran derivatives as PPARα and/or PPARγ activators
- Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPARα/PPARγ Agonist Activity and Anti-inflammatory Effect
- Tissue distribution of Peroxisome proliferator-activated receptors in salmon fish (Salmo salar L.)
- Effects of IFN-γ coding plasmid supplementation in the immune response and protection elicited by Trypanosoma cruzi attenuated parasites
- Determination of relation between αS1 casein concentration and coagulation properties of goat milk
- Caracterización de α-S caseínas en leche de cabra de diferentes razas de importancia comercial
- Attempt to increasing freshness in gluten-free tin bread by adding distilled monoglycerides, α-amylase and glucose oxidase