A novel grapevine badnavirus is associated with the Roditis leaf discoloration disease

Roditis leaf discoloration (RLD), a graft-transmissible disease of grapevine, was first reported in Greece in the 1980s. Even though various native grapevine viruses were identified in the affected vines, the etiology of the disease remained unknown. In the present study, we used an NGS platform for...

Descripción completa

Detalles Bibliográficos
Autores principales: Maliogka, Varvara, Olmos, Antonio, Pappi, Polyxeni G., Lotos, Leonidas, Efthimiou, Konstantinos, Grammatikaki, Garyfalia, Candresse, Thierry, Katis, Nikolaos, Avgelis, Apostolos D.
Formato: article
Lenguaje:Inglés
Publicado: 2017
Acceso en línea:http://hdl.handle.net/20.500.11939/5558
https://www.sciencedirect.com/science/article/abs/pii/S0168170215001215?via%3Dihub
_version_ 1855032297571483648
author Maliogka, Varvara
Olmos, Antonio
Pappi, Polyxeni G.
Lotos, Leonidas
Efthimiou, Konstantinos
Grammatikaki, Garyfalia
Candresse, Thierry
Katis, Nikolaos
Avgelis, Apostolos D.
author_browse Avgelis, Apostolos D.
Candresse, Thierry
Efthimiou, Konstantinos
Grammatikaki, Garyfalia
Katis, Nikolaos
Lotos, Leonidas
Maliogka, Varvara
Olmos, Antonio
Pappi, Polyxeni G.
author_facet Maliogka, Varvara
Olmos, Antonio
Pappi, Polyxeni G.
Lotos, Leonidas
Efthimiou, Konstantinos
Grammatikaki, Garyfalia
Candresse, Thierry
Katis, Nikolaos
Avgelis, Apostolos D.
author_sort Maliogka, Varvara
collection ReDivia
description Roditis leaf discoloration (RLD), a graft-transmissible disease of grapevine, was first reported in Greece in the 1980s. Even though various native grapevine viruses were identified in the affected vines, the etiology of the disease remained unknown. In the present study, we used an NGS platform for sequencing siRNAs from a twenty-year old Roditis vine showing typical RLD symptoms. Analysis of the NGS data revealed the presence of various known grapevine viruses and viroids as well as a hitherto uncharacterized DNA virus. The circular genome of the new virus was fully reassembled. It is 6988 nts long and includes 4 open reading frames (ORFs). ORF1, ORF2 and ORF4 code for proteins with unknown functions while ORF3 encodes a polyprotein with motifs related to the replication, encapsidation and movement of the virus. Phylogenetic analysis classified the novel virus within the genus Badnavirus, with closest relationship to Fig badnavirus 1. Further studies showed that the new badnavirus is closely related with the RLD disease and the provisional name grapevine Roditis leaf discoloration-associated virus (GRLDaV) is proposed. Our findings extend the number of DNA viruses identified in grapevine, further drawing attention to the potential importance of this virus group on grapevine pathology.
format article
id ReDivia5558
institution Instituto Valenciano de Investigaciones Agrarias (IVIA)
language Inglés
publishDate 2017
publishDateRange 2017
publishDateSort 2017
record_format dspace
spelling ReDivia55582025-04-25T14:43:17Z A novel grapevine badnavirus is associated with the Roditis leaf discoloration disease Maliogka, Varvara Olmos, Antonio Pappi, Polyxeni G. Lotos, Leonidas Efthimiou, Konstantinos Grammatikaki, Garyfalia Candresse, Thierry Katis, Nikolaos Avgelis, Apostolos D. Roditis leaf discoloration (RLD), a graft-transmissible disease of grapevine, was first reported in Greece in the 1980s. Even though various native grapevine viruses were identified in the affected vines, the etiology of the disease remained unknown. In the present study, we used an NGS platform for sequencing siRNAs from a twenty-year old Roditis vine showing typical RLD symptoms. Analysis of the NGS data revealed the presence of various known grapevine viruses and viroids as well as a hitherto uncharacterized DNA virus. The circular genome of the new virus was fully reassembled. It is 6988 nts long and includes 4 open reading frames (ORFs). ORF1, ORF2 and ORF4 code for proteins with unknown functions while ORF3 encodes a polyprotein with motifs related to the replication, encapsidation and movement of the virus. Phylogenetic analysis classified the novel virus within the genus Badnavirus, with closest relationship to Fig badnavirus 1. Further studies showed that the new badnavirus is closely related with the RLD disease and the provisional name grapevine Roditis leaf discoloration-associated virus (GRLDaV) is proposed. Our findings extend the number of DNA viruses identified in grapevine, further drawing attention to the potential importance of this virus group on grapevine pathology. 2017-06-01T10:12:33Z 2017-06-01T10:12:33Z 2015 MAY 4 2015 article Maliogka, V. I., Olmos, A., Pappi, P. G., Lotos, L., Efthimiou, K., Grammatikaki, G. et al. (2015). A novel grapevine badnavirus is associated with the Roditis leaf discoloration disease. Virus research, 203, 47-55. 0168-1702 http://hdl.handle.net/20.500.11939/5558 10.1016/j.virusres.2015.03.003 https://www.sciencedirect.com/science/article/abs/pii/S0168170215001215?via%3Dihub en openAccess Impreso
spellingShingle Maliogka, Varvara
Olmos, Antonio
Pappi, Polyxeni G.
Lotos, Leonidas
Efthimiou, Konstantinos
Grammatikaki, Garyfalia
Candresse, Thierry
Katis, Nikolaos
Avgelis, Apostolos D.
A novel grapevine badnavirus is associated with the Roditis leaf discoloration disease
title A novel grapevine badnavirus is associated with the Roditis leaf discoloration disease
title_full A novel grapevine badnavirus is associated with the Roditis leaf discoloration disease
title_fullStr A novel grapevine badnavirus is associated with the Roditis leaf discoloration disease
title_full_unstemmed A novel grapevine badnavirus is associated with the Roditis leaf discoloration disease
title_short A novel grapevine badnavirus is associated with the Roditis leaf discoloration disease
title_sort novel grapevine badnavirus is associated with the roditis leaf discoloration disease
url http://hdl.handle.net/20.500.11939/5558
https://www.sciencedirect.com/science/article/abs/pii/S0168170215001215?via%3Dihub
work_keys_str_mv AT maliogkavarvara anovelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT olmosantonio anovelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT pappipolyxenig anovelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT lotosleonidas anovelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT efthimioukonstantinos anovelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT grammatikakigaryfalia anovelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT candressethierry anovelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT katisnikolaos anovelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT avgelisapostolosd anovelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT maliogkavarvara novelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT olmosantonio novelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT pappipolyxenig novelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT lotosleonidas novelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT efthimioukonstantinos novelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT grammatikakigaryfalia novelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT candressethierry novelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT katisnikolaos novelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease
AT avgelisapostolosd novelgrapevinebadnavirusisassociatedwiththeroditisleafdiscolorationdisease