Cytological and molecular characterization of three gametoclones of Citrus clementina

Background: Three gametoclonal plants of Citrus clementina Hort. ex Tan., cv. Nules, designated ESP, FRA, and ITA (derived from three labs in Spain, France, and Italy, respectively), were selected for cytological and molecular characterization in order to elucidate genomic rearrangements provoked by...

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Autores principales: Germana, Maria Antonietta, Aleza, Pablo, Carrera, Esther, Chen, Chunxian, Chiancone, Benedetta, Costantino, Gilles, Dambier, Dominique, Deng, Xiuxin, Federici, Claire T., Froelicher, Yann, Guo, Wenwu, Ibanez, Victoria, Juárez, José, Kwok, Kevin, Luro, Francois, Machado, Marcos Antonio, Naranjo, Miguel A., Navarro, Luis, Ollitrault, Patrick, Ríos, Gabino, Roose, Mikeal L., Talón, Manuel, Xu, Qiang, Gmitter Jr., Frederick G.
Formato: Artículo
Lenguaje:Inglés
Publicado: 2017
Acceso en línea:http://hdl.handle.net/20.500.11939/5263
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author Germana, Maria Antonietta
Aleza, Pablo
Carrera, Esther
Chen, Chunxian
Chiancone, Benedetta
Costantino, Gilles
Dambier, Dominique
Deng, Xiuxin
Federici, Claire T.
Froelicher, Yann
Guo, Wenwu
Ibanez, Victoria
Juárez, José
Kwok, Kevin
Luro, Francois
Machado, Marcos Antonio
Naranjo, Miguel A.
Navarro, Luis
Ollitrault, Patrick
Ríos, Gabino
Roose, Mikeal L.
Talón, Manuel
Xu, Qiang
Gmitter Jr., Frederick G.
author_browse Aleza, Pablo
Carrera, Esther
Chen, Chunxian
Chiancone, Benedetta
Costantino, Gilles
Dambier, Dominique
Deng, Xiuxin
Federici, Claire T.
Froelicher, Yann
Germana, Maria Antonietta
Gmitter Jr., Frederick G.
Guo, Wenwu
Ibanez, Victoria
Juárez, José
Kwok, Kevin
Luro, Francois
Machado, Marcos Antonio
Naranjo, Miguel A.
Navarro, Luis
Ollitrault, Patrick
Roose, Mikeal L.
Ríos, Gabino
Talón, Manuel
Xu, Qiang
author_facet Germana, Maria Antonietta
Aleza, Pablo
Carrera, Esther
Chen, Chunxian
Chiancone, Benedetta
Costantino, Gilles
Dambier, Dominique
Deng, Xiuxin
Federici, Claire T.
Froelicher, Yann
Guo, Wenwu
Ibanez, Victoria
Juárez, José
Kwok, Kevin
Luro, Francois
Machado, Marcos Antonio
Naranjo, Miguel A.
Navarro, Luis
Ollitrault, Patrick
Ríos, Gabino
Roose, Mikeal L.
Talón, Manuel
Xu, Qiang
Gmitter Jr., Frederick G.
author_sort Germana, Maria Antonietta
collection ReDivia
description Background: Three gametoclonal plants of Citrus clementina Hort. ex Tan., cv. Nules, designated ESP, FRA, and ITA (derived from three labs in Spain, France, and Italy, respectively), were selected for cytological and molecular characterization in order to elucidate genomic rearrangements provoked by haploidization. The study included comparisons of their ploidy, homozygosity, genome integrity, and gene dosage, using chromosome counting, flow cytometry, SSR marker genotyping, and array-Comparative Genomic Hybridization (array-CGH). Results: Chromosome counting and flow cytometry revealed that ESP and FRA were haploid, but ITA was tri-haploid. Homozygous patterns, represented by a single peak (allele), were observed among the three plants at almost all SSR loci distributed across the entire diploid donor genome. Those few loci with extra peaks visualized as output from automated sequencing runs, generally low or ambiguous, might result from amplicons of paralogous members at the locus, non-specific sites, or unexpected recombinant alleles. No new alleles were found, suggesting the genomes remained stable and intact during gametogenesis and regeneration. The integrity of the haploid genome also was supported by array-CGH studies, in which genomic profiles were comparable to the diploid control. Conclusions: The presence of few gene hybridization abnormalities, corroborated by gene dosage measurements, were hypothetically due to the segregation of hemizygous alleles and minor genomic rearrangements occurring during the haploidization procedure. In conclusion, these plants that are valuable genetic and breeding materials contain completely homozygous and essentially intact genomes.
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spelling ReDivia52632025-04-25T14:45:48Z Cytological and molecular characterization of three gametoclones of Citrus clementina Germana, Maria Antonietta Aleza, Pablo Carrera, Esther Chen, Chunxian Chiancone, Benedetta Costantino, Gilles Dambier, Dominique Deng, Xiuxin Federici, Claire T. Froelicher, Yann Guo, Wenwu Ibanez, Victoria Juárez, José Kwok, Kevin Luro, Francois Machado, Marcos Antonio Naranjo, Miguel A. Navarro, Luis Ollitrault, Patrick Ríos, Gabino Roose, Mikeal L. Talón, Manuel Xu, Qiang Gmitter Jr., Frederick G. Background: Three gametoclonal plants of Citrus clementina Hort. ex Tan., cv. Nules, designated ESP, FRA, and ITA (derived from three labs in Spain, France, and Italy, respectively), were selected for cytological and molecular characterization in order to elucidate genomic rearrangements provoked by haploidization. The study included comparisons of their ploidy, homozygosity, genome integrity, and gene dosage, using chromosome counting, flow cytometry, SSR marker genotyping, and array-Comparative Genomic Hybridization (array-CGH). Results: Chromosome counting and flow cytometry revealed that ESP and FRA were haploid, but ITA was tri-haploid. Homozygous patterns, represented by a single peak (allele), were observed among the three plants at almost all SSR loci distributed across the entire diploid donor genome. Those few loci with extra peaks visualized as output from automated sequencing runs, generally low or ambiguous, might result from amplicons of paralogous members at the locus, non-specific sites, or unexpected recombinant alleles. No new alleles were found, suggesting the genomes remained stable and intact during gametogenesis and regeneration. The integrity of the haploid genome also was supported by array-CGH studies, in which genomic profiles were comparable to the diploid control. Conclusions: The presence of few gene hybridization abnormalities, corroborated by gene dosage measurements, were hypothetically due to the segregation of hemizygous alleles and minor genomic rearrangements occurring during the haploidization procedure. In conclusion, these plants that are valuable genetic and breeding materials contain completely homozygous and essentially intact genomes. 2017-06-01T10:12:00Z 2017-06-01T10:12:00Z 2013 SEP 10 2013 article publishedVersion Germana, M. A., Aleza, P., Carrera, E., Chen, C., Chiancone, B., Costantino, G., et al. (2013). Cytological and molecular characterization of three gametoclones of citrus clementina. Bmc Plant Biology, 13, 129. 1471-2229 http://hdl.handle.net/20.500.11939/5263 10.1186/1471-2229-13-129 en openAccess Impreso
spellingShingle Germana, Maria Antonietta
Aleza, Pablo
Carrera, Esther
Chen, Chunxian
Chiancone, Benedetta
Costantino, Gilles
Dambier, Dominique
Deng, Xiuxin
Federici, Claire T.
Froelicher, Yann
Guo, Wenwu
Ibanez, Victoria
Juárez, José
Kwok, Kevin
Luro, Francois
Machado, Marcos Antonio
Naranjo, Miguel A.
Navarro, Luis
Ollitrault, Patrick
Ríos, Gabino
Roose, Mikeal L.
Talón, Manuel
Xu, Qiang
Gmitter Jr., Frederick G.
Cytological and molecular characterization of three gametoclones of Citrus clementina
title Cytological and molecular characterization of three gametoclones of Citrus clementina
title_full Cytological and molecular characterization of three gametoclones of Citrus clementina
title_fullStr Cytological and molecular characterization of three gametoclones of Citrus clementina
title_full_unstemmed Cytological and molecular characterization of three gametoclones of Citrus clementina
title_short Cytological and molecular characterization of three gametoclones of Citrus clementina
title_sort cytological and molecular characterization of three gametoclones of citrus clementina
url http://hdl.handle.net/20.500.11939/5263
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