Complete nucleotide sequence of a Spanish isolate of Parietaria mottle virus infecting tomato

The genome of a Spanish isolate of Parietaria mottle virus (PMoV) obtained from tomato (strain PMoV-T) was completely sequenced. Protein motifs conserved for RNA viruses were identified: the p1 protein contained a metyltransferase domain in its N-terminal half and a triphosphatase/helicase domain in...

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Autores principales: Galipienso, Luis, Rubio, Luis, Lopez, Carmelo, Soler, Salvador, Aramburu, Jose
Formato: article
Lenguaje:Inglés
Publicado: 2017
Acceso en línea:http://hdl.handle.net/20.500.11939/5228
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author Galipienso, Luis
Rubio, Luis
Lopez, Carmelo
Soler, Salvador
Aramburu, Jose
author_browse Aramburu, Jose
Galipienso, Luis
Lopez, Carmelo
Rubio, Luis
Soler, Salvador
author_facet Galipienso, Luis
Rubio, Luis
Lopez, Carmelo
Soler, Salvador
Aramburu, Jose
author_sort Galipienso, Luis
collection ReDivia
description The genome of a Spanish isolate of Parietaria mottle virus (PMoV) obtained from tomato (strain PMoV-T) was completely sequenced. Protein motifs conserved for RNA viruses were identified: the p1 protein contained a metyltransferase domain in its N-terminal half and a triphosphatase/helicase domain in its C-terminal half, the p2 protein contained a RNA polymerase domain; the 3a protein contained a RNA-binding domain with alpha-helix and beta-sheet secondary structures. In addition, stem-loop structures with potential capacity of protein interactions were predicted on the untranslated terminal regions. Comparison with the other sequenced PMoV isolate showed nucleotide identities of 93, 90, and 93% for genomic RNAs 1, 2 and 3, respectively, and amino acid identities ranging from 88 to 97% for the different proteins. A cytosine deletion was detected at position 1,366 of RNA 3, involving a start codon for the coat protein (CP) gene different from the other PMoV isolate, resulting in a CP 16 amino acids shorter. Comparison of synonymous and nonsynonymous mutations revealed different selective constraints along the genome.
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spelling ReDivia52282025-04-25T14:45:42Z Complete nucleotide sequence of a Spanish isolate of Parietaria mottle virus infecting tomato Galipienso, Luis Rubio, Luis Lopez, Carmelo Soler, Salvador Aramburu, Jose The genome of a Spanish isolate of Parietaria mottle virus (PMoV) obtained from tomato (strain PMoV-T) was completely sequenced. Protein motifs conserved for RNA viruses were identified: the p1 protein contained a metyltransferase domain in its N-terminal half and a triphosphatase/helicase domain in its C-terminal half, the p2 protein contained a RNA polymerase domain; the 3a protein contained a RNA-binding domain with alpha-helix and beta-sheet secondary structures. In addition, stem-loop structures with potential capacity of protein interactions were predicted on the untranslated terminal regions. Comparison with the other sequenced PMoV isolate showed nucleotide identities of 93, 90, and 93% for genomic RNAs 1, 2 and 3, respectively, and amino acid identities ranging from 88 to 97% for the different proteins. A cytosine deletion was detected at position 1,366 of RNA 3, involving a start codon for the coat protein (CP) gene different from the other PMoV isolate, resulting in a CP 16 amino acids shorter. Comparison of synonymous and nonsynonymous mutations revealed different selective constraints along the genome. 2017-06-01T10:11:55Z 2017-06-01T10:11:55Z 2009 OCT 2009 article Galipienso, L., Rubio, L., Lopez, Carmelo, Soler, Salvador, Aramburu, J. (2009). Complete nucleotide sequence of a Spanish isolate of Parietaria mottle virus infecting tomato. Virus genes, 39(2), 256-260. 0920-8569 http://hdl.handle.net/20.500.11939/5228 10.1007/s11262-009-0388-4 en openAccess Impreso
spellingShingle Galipienso, Luis
Rubio, Luis
Lopez, Carmelo
Soler, Salvador
Aramburu, Jose
Complete nucleotide sequence of a Spanish isolate of Parietaria mottle virus infecting tomato
title Complete nucleotide sequence of a Spanish isolate of Parietaria mottle virus infecting tomato
title_full Complete nucleotide sequence of a Spanish isolate of Parietaria mottle virus infecting tomato
title_fullStr Complete nucleotide sequence of a Spanish isolate of Parietaria mottle virus infecting tomato
title_full_unstemmed Complete nucleotide sequence of a Spanish isolate of Parietaria mottle virus infecting tomato
title_short Complete nucleotide sequence of a Spanish isolate of Parietaria mottle virus infecting tomato
title_sort complete nucleotide sequence of a spanish isolate of parietaria mottle virus infecting tomato
url http://hdl.handle.net/20.500.11939/5228
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