Genetic variability and evolutionary analysis of parietaria mottle virus: role of selection and genetic exchange

The genetic variability and evolution of parietaria mottle virus (PMoV) of the genus Ilarvirus was studied by analyzing nucleotide sequences of 2b and CP genes from isolates collected in different countries. Phylogenetic analysis showed that PMoV isolates clustered in different clades: one (clade I)...

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Main Authors: Galipienso, Luis, Martínez, Carolina, Willemsen, Anouk, Alfaro-Fernández, Ana, Font-San-Ambrosio, Isabel, Davino, Salvatore, Rubio, Luis
Format: article
Language:Inglés
Published: 2017
Online Access:http://hdl.handle.net/20.500.11939/5225
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author Galipienso, Luis
Martínez, Carolina
Willemsen, Anouk
Alfaro-Fernández, Ana
Font-San-Ambrosio, Isabel
Davino, Salvatore
Rubio, Luis
author_browse Alfaro-Fernández, Ana
Davino, Salvatore
Font-San-Ambrosio, Isabel
Galipienso, Luis
Martínez, Carolina
Rubio, Luis
Willemsen, Anouk
author_facet Galipienso, Luis
Martínez, Carolina
Willemsen, Anouk
Alfaro-Fernández, Ana
Font-San-Ambrosio, Isabel
Davino, Salvatore
Rubio, Luis
author_sort Galipienso, Luis
collection ReDivia
description The genetic variability and evolution of parietaria mottle virus (PMoV) of the genus Ilarvirus was studied by analyzing nucleotide sequences of 2b and CP genes from isolates collected in different countries. Phylogenetic analysis showed that PMoV isolates clustered in different clades: one (clade I) composed of only Italian isolates and three clades (clades II-IV) including the Spanish isolates. The Greek isolate GrT-1 used in this study was in clade IV for the CP phylogenetic tree whereas it formed a separate branch in the 2b phylogenetic tree. The nucleotide sequence diversity of both the 2b and CP genes was low (0.062 +/- A 0.006 and 0.063 +/- A 0.006 for 2b and CP, respectively) but higher than those of other ilarviruses. Distribution of synonymous and nonsynonymous substitutions revealed that 2b and CP proteins are under purifying selection, with some positions under diversifying selection. Genetic exchange among Spanish isolates was also detected.
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spelling ReDivia52252025-04-25T14:45:42Z Genetic variability and evolutionary analysis of parietaria mottle virus: role of selection and genetic exchange Galipienso, Luis Martínez, Carolina Willemsen, Anouk Alfaro-Fernández, Ana Font-San-Ambrosio, Isabel Davino, Salvatore Rubio, Luis The genetic variability and evolution of parietaria mottle virus (PMoV) of the genus Ilarvirus was studied by analyzing nucleotide sequences of 2b and CP genes from isolates collected in different countries. Phylogenetic analysis showed that PMoV isolates clustered in different clades: one (clade I) composed of only Italian isolates and three clades (clades II-IV) including the Spanish isolates. The Greek isolate GrT-1 used in this study was in clade IV for the CP phylogenetic tree whereas it formed a separate branch in the 2b phylogenetic tree. The nucleotide sequence diversity of both the 2b and CP genes was low (0.062 +/- A 0.006 and 0.063 +/- A 0.006 for 2b and CP, respectively) but higher than those of other ilarviruses. Distribution of synonymous and nonsynonymous substitutions revealed that 2b and CP proteins are under purifying selection, with some positions under diversifying selection. Genetic exchange among Spanish isolates was also detected. 2017-06-01T10:11:55Z 2017-06-01T10:11:55Z 2015 OCT 2015 article Galipienso, L., Martinez, Carolina, Willemsen, Anouk, Alfaro-Fernandez, Ana, Font-San Ambrosio, I., Davino, Salvatore, Rubio, L. (2015). Genetic variability and evolutionary analysis of parietaria mottle virus: role of selection and genetic exchange. Archives of Virology, 160(10), 2611-2616. 0304-8608 http://hdl.handle.net/20.500.11939/5225 10.1007/s00705-015-2550-8 en openAccess Impreso
spellingShingle Galipienso, Luis
Martínez, Carolina
Willemsen, Anouk
Alfaro-Fernández, Ana
Font-San-Ambrosio, Isabel
Davino, Salvatore
Rubio, Luis
Genetic variability and evolutionary analysis of parietaria mottle virus: role of selection and genetic exchange
title Genetic variability and evolutionary analysis of parietaria mottle virus: role of selection and genetic exchange
title_full Genetic variability and evolutionary analysis of parietaria mottle virus: role of selection and genetic exchange
title_fullStr Genetic variability and evolutionary analysis of parietaria mottle virus: role of selection and genetic exchange
title_full_unstemmed Genetic variability and evolutionary analysis of parietaria mottle virus: role of selection and genetic exchange
title_short Genetic variability and evolutionary analysis of parietaria mottle virus: role of selection and genetic exchange
title_sort genetic variability and evolutionary analysis of parietaria mottle virus role of selection and genetic exchange
url http://hdl.handle.net/20.500.11939/5225
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