Recombination profiles between Tomato yellow leaf curl virus and Tomato yellow leaf curl Sardinia virus in laboratory and field conditions: evolutionary and taxonomic implications

Tomato yellow leaf curl Sardinia virus and Tomato yellow leaf curl virus have co-existed in Italian tomato crops since 2002 and have reached equilibrium, with plants hosting molecules of both species plus their recombinants being the most frequent case. Recombination events are studied in field samp...

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Autores principales: Davino, Salvatore, Miozzi, Laura, Panno, Stefano, Rubio, Luis, Davino, Mario, Accotto, Gian Paolo
Formato: article
Lenguaje:Inglés
Publicado: 2017
Acceso en línea:http://hdl.handle.net/20.500.11939/5085
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author Davino, Salvatore
Miozzi, Laura
Panno, Stefano
Rubio, Luis
Davino, Mario
Accotto, Gian Paolo
author_browse Accotto, Gian Paolo
Davino, Mario
Davino, Salvatore
Miozzi, Laura
Panno, Stefano
Rubio, Luis
author_facet Davino, Salvatore
Miozzi, Laura
Panno, Stefano
Rubio, Luis
Davino, Mario
Accotto, Gian Paolo
author_sort Davino, Salvatore
collection ReDivia
description Tomato yellow leaf curl Sardinia virus and Tomato yellow leaf curl virus have co-existed in Italian tomato crops since 2002 and have reached equilibrium, with plants hosting molecules of both species plus their recombinants being the most frequent case. Recombination events are studied in field samples, as well as in experimental co-infections, when recombinants were detected as early as 45 days following inoculation. In both conditions, recombination breakpoints were essentially absent in regions corresponding to ORFs V2, CP and C4, whereas density was highest in the 3'-terminal portion of ORF C3, next to the region where the two transcription units co-terminate. The vast majority of breakpoints were mapped at antisense ORFs, supporting speculation that the rolling-circle replication mechanism, and the existence of sense and antisense ORFs on the circular genome, may result in clashes between replication and transcription complexes.
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spelling ReDivia50852025-04-25T14:45:20Z Recombination profiles between Tomato yellow leaf curl virus and Tomato yellow leaf curl Sardinia virus in laboratory and field conditions: evolutionary and taxonomic implications Davino, Salvatore Miozzi, Laura Panno, Stefano Rubio, Luis Davino, Mario Accotto, Gian Paolo Tomato yellow leaf curl Sardinia virus and Tomato yellow leaf curl virus have co-existed in Italian tomato crops since 2002 and have reached equilibrium, with plants hosting molecules of both species plus their recombinants being the most frequent case. Recombination events are studied in field samples, as well as in experimental co-infections, when recombinants were detected as early as 45 days following inoculation. In both conditions, recombination breakpoints were essentially absent in regions corresponding to ORFs V2, CP and C4, whereas density was highest in the 3'-terminal portion of ORF C3, next to the region where the two transcription units co-terminate. The vast majority of breakpoints were mapped at antisense ORFs, supporting speculation that the rolling-circle replication mechanism, and the existence of sense and antisense ORFs on the circular genome, may result in clashes between replication and transcription complexes. 2017-06-01T10:11:41Z 2017-06-01T10:11:41Z 2012 DEC 2012 article Davino, Salvatore, Miozzi, L., Panno, Stefano, Rubio, L., Davino, Mario, Accotto, Gian Paolo (2012). Recombination profiles between Tomato yellow leaf curl virus and Tomato yellow leaf curl Sardinia virus in laboratory and field conditions: evolutionary and taxonomic implications. Journal of General Virology, 93, 2712-2717. 0022-1317 http://hdl.handle.net/20.500.11939/5085 10.1099/vir.0.045773-0 en openAccess Impreso
spellingShingle Davino, Salvatore
Miozzi, Laura
Panno, Stefano
Rubio, Luis
Davino, Mario
Accotto, Gian Paolo
Recombination profiles between Tomato yellow leaf curl virus and Tomato yellow leaf curl Sardinia virus in laboratory and field conditions: evolutionary and taxonomic implications
title Recombination profiles between Tomato yellow leaf curl virus and Tomato yellow leaf curl Sardinia virus in laboratory and field conditions: evolutionary and taxonomic implications
title_full Recombination profiles between Tomato yellow leaf curl virus and Tomato yellow leaf curl Sardinia virus in laboratory and field conditions: evolutionary and taxonomic implications
title_fullStr Recombination profiles between Tomato yellow leaf curl virus and Tomato yellow leaf curl Sardinia virus in laboratory and field conditions: evolutionary and taxonomic implications
title_full_unstemmed Recombination profiles between Tomato yellow leaf curl virus and Tomato yellow leaf curl Sardinia virus in laboratory and field conditions: evolutionary and taxonomic implications
title_short Recombination profiles between Tomato yellow leaf curl virus and Tomato yellow leaf curl Sardinia virus in laboratory and field conditions: evolutionary and taxonomic implications
title_sort recombination profiles between tomato yellow leaf curl virus and tomato yellow leaf curl sardinia virus in laboratory and field conditions evolutionary and taxonomic implications
url http://hdl.handle.net/20.500.11939/5085
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