Maximum-likelihood method identifies meiotic restitution mechanism from heterozygosity transmission of centromeric loci: application in citrus

Polyploidisation is a key source of diversification and speciation in plants. Most researchers consider sexual polyploidisation leading to unreduced gamete as its main origin. Unreduced gametes are useful in several crop breeding schemes. Their formation mechanism, i.e., First-Division Restitution (...

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Autores principales: Cuenca, José, Aleza, Pablo, Juárez, José, García-Lor, Andrés, Froelicher, Yann, Navarro, Luis, Ollitrault, Patrick
Formato: article
Lenguaje:Inglés
Publicado: 2017
Acceso en línea:http://hdl.handle.net/20.500.11939/5069
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author Cuenca, José
Aleza, Pablo
Juárez, José
García-Lor, Andrés
Froelicher, Yann
Navarro, Luis
Ollitrault, Patrick
author_browse Aleza, Pablo
Cuenca, José
Froelicher, Yann
García-Lor, Andrés
Juárez, José
Navarro, Luis
Ollitrault, Patrick
author_facet Cuenca, José
Aleza, Pablo
Juárez, José
García-Lor, Andrés
Froelicher, Yann
Navarro, Luis
Ollitrault, Patrick
author_sort Cuenca, José
collection ReDivia
description Polyploidisation is a key source of diversification and speciation in plants. Most researchers consider sexual polyploidisation leading to unreduced gamete as its main origin. Unreduced gametes are useful in several crop breeding schemes. Their formation mechanism, i.e., First-Division Restitution (FDR) or Second-Division Restitution (SDR), greatly impacts the gametic and population structures and, therefore, the breeding efficiency. Previous methods to identify the underlying mechanism required the analysis of a large set of markers over large progeny. This work develops a new maximum-likelihood method to identify the unreduced gamete formation mechanism both at the population and individual levels using independent centromeric markers. Knowledge of marker-centromere distances greatly improves the statistical power of the comparison between the SDR and FDR hypotheses. Simulating data demonstrated the importance of selecting markers very close to the centromere to obtain significant conclusions at individual level. This new method was used to identify the meiotic restitution mechanism in nineteen mandarin genotypes used as female parents in triploid citrus breeding. SDR was identified for 85.3% of 543 triploid hybrids and FDR for 0.6%. No significant conclusions were obtained for 14.1% of the hybrids. At population level SDR was the predominant mechanisms for the 19 parental mandarins.
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spelling ReDivia50692025-04-25T14:45:17Z Maximum-likelihood method identifies meiotic restitution mechanism from heterozygosity transmission of centromeric loci: application in citrus Cuenca, José Aleza, Pablo Juárez, José García-Lor, Andrés Froelicher, Yann Navarro, Luis Ollitrault, Patrick Polyploidisation is a key source of diversification and speciation in plants. Most researchers consider sexual polyploidisation leading to unreduced gamete as its main origin. Unreduced gametes are useful in several crop breeding schemes. Their formation mechanism, i.e., First-Division Restitution (FDR) or Second-Division Restitution (SDR), greatly impacts the gametic and population structures and, therefore, the breeding efficiency. Previous methods to identify the underlying mechanism required the analysis of a large set of markers over large progeny. This work develops a new maximum-likelihood method to identify the unreduced gamete formation mechanism both at the population and individual levels using independent centromeric markers. Knowledge of marker-centromere distances greatly improves the statistical power of the comparison between the SDR and FDR hypotheses. Simulating data demonstrated the importance of selecting markers very close to the centromere to obtain significant conclusions at individual level. This new method was used to identify the meiotic restitution mechanism in nineteen mandarin genotypes used as female parents in triploid citrus breeding. SDR was identified for 85.3% of 543 triploid hybrids and FDR for 0.6%. No significant conclusions were obtained for 14.1% of the hybrids. At population level SDR was the predominant mechanisms for the 19 parental mandarins. 2017-06-01T10:11:39Z 2017-06-01T10:11:39Z 2015 APR 20 article publishedVersion Cuenca, J., Aleza, P., Juarez, J., García-Lor, A., Froelicher, Y., Navarro, L., & Ollitrault, P. (2015). Maximum-likelihood method identifies meiotic restitution mechanism from heterozygosity transmission of centromeric loci: application in citrus. Scientific reports, 5, 9897. 2045-2322 http://hdl.handle.net/20.500.11939/5069 10.1038/srep09897 en openAccess Impreso
spellingShingle Cuenca, José
Aleza, Pablo
Juárez, José
García-Lor, Andrés
Froelicher, Yann
Navarro, Luis
Ollitrault, Patrick
Maximum-likelihood method identifies meiotic restitution mechanism from heterozygosity transmission of centromeric loci: application in citrus
title Maximum-likelihood method identifies meiotic restitution mechanism from heterozygosity transmission of centromeric loci: application in citrus
title_full Maximum-likelihood method identifies meiotic restitution mechanism from heterozygosity transmission of centromeric loci: application in citrus
title_fullStr Maximum-likelihood method identifies meiotic restitution mechanism from heterozygosity transmission of centromeric loci: application in citrus
title_full_unstemmed Maximum-likelihood method identifies meiotic restitution mechanism from heterozygosity transmission of centromeric loci: application in citrus
title_short Maximum-likelihood method identifies meiotic restitution mechanism from heterozygosity transmission of centromeric loci: application in citrus
title_sort maximum likelihood method identifies meiotic restitution mechanism from heterozygosity transmission of centromeric loci application in citrus
url http://hdl.handle.net/20.500.11939/5069
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