Enrichment double-antibody sandwich indirect enzyme-linked immunosorbent assay that uses a specific monoclonal antibody for sensitive detection of Ralstonia solanacearum in asymptomatic potato tubers

Sensitive and specific routine detection of Ralstonia solanacearum in symptomless potato tubers was achieved by efficient enrichment followed by a reliable double-antibody sandwich indirect enzyme-linked immunosorbent assay based on the specific monoclonal antibody 8B-IVIA. This monoclonal antibody...

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Autores principales: Caruso, Paola, Gorris, María T., Cambra, Mariano, Palomo, José L., Collar, Jesús, López, María M.
Formato: article
Lenguaje:Inglés
Publicado: 2017
Acceso en línea:http://hdl.handle.net/20.500.11939/4978
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author Caruso, Paola
Gorris, María T.
Cambra, Mariano
Palomo, José L.
Collar, Jesús
López, María M.
author_browse Cambra, Mariano
Caruso, Paola
Collar, Jesús
Gorris, María T.
López, María M.
Palomo, José L.
author_facet Caruso, Paola
Gorris, María T.
Cambra, Mariano
Palomo, José L.
Collar, Jesús
López, María M.
author_sort Caruso, Paola
collection ReDivia
description Sensitive and specific routine detection of Ralstonia solanacearum in symptomless potato tubers was achieved by efficient enrichment followed by a reliable double-antibody sandwich indirect enzyme-linked immunosorbent assay based on the specific monoclonal antibody 8B-IVIA. This monoclonal antibody reacted with 168 typical R. solanacearum strains and did not recognize 174 other pathogenic or unidentified bacteria isolated from potato. The optimized protocol included an initial enrichment step consisting of shaking the samples in modified Wilbrink broth for 72 h at 29degreesC. This step enabled specific detection by the enzyme-linked immunosorbent assay of 1 to 10 CFU of R. solanacearum per ml of initial potato extract. Analysis of 233 commercial potato lots by this method provided results that coincided with the results of conventional methods.
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spelling ReDivia49782025-04-25T14:45:04Z Enrichment double-antibody sandwich indirect enzyme-linked immunosorbent assay that uses a specific monoclonal antibody for sensitive detection of Ralstonia solanacearum in asymptomatic potato tubers Caruso, Paola Gorris, María T. Cambra, Mariano Palomo, José L. Collar, Jesús López, María M. Sensitive and specific routine detection of Ralstonia solanacearum in symptomless potato tubers was achieved by efficient enrichment followed by a reliable double-antibody sandwich indirect enzyme-linked immunosorbent assay based on the specific monoclonal antibody 8B-IVIA. This monoclonal antibody reacted with 168 typical R. solanacearum strains and did not recognize 174 other pathogenic or unidentified bacteria isolated from potato. The optimized protocol included an initial enrichment step consisting of shaking the samples in modified Wilbrink broth for 72 h at 29degreesC. This step enabled specific detection by the enzyme-linked immunosorbent assay of 1 to 10 CFU of R. solanacearum per ml of initial potato extract. Analysis of 233 commercial potato lots by this method provided results that coincided with the results of conventional methods. 2017-06-01T10:11:29Z 2017-06-01T10:11:29Z 2002 JUL 2002 article Caruso, P., Gorris, M. T., Cambra, M., Palomo, J.L., Collar, J., Lopez, M.M. (2002). Enrichment double-antibody sandwich indirect enzyme-linked immunosorbent assay that uses a specific monoclonal antibody for sensitive detection of Ralstonia solanacearum in asymptomatic potato tubers. Applied and Environmental Microbiology, 68(7), 3634-3638. 0099-2240 http://hdl.handle.net/20.500.11939/4978 10.1128/AEM.68.7.3634-3638.2002 en openAccess Impreso
spellingShingle Caruso, Paola
Gorris, María T.
Cambra, Mariano
Palomo, José L.
Collar, Jesús
López, María M.
Enrichment double-antibody sandwich indirect enzyme-linked immunosorbent assay that uses a specific monoclonal antibody for sensitive detection of Ralstonia solanacearum in asymptomatic potato tubers
title Enrichment double-antibody sandwich indirect enzyme-linked immunosorbent assay that uses a specific monoclonal antibody for sensitive detection of Ralstonia solanacearum in asymptomatic potato tubers
title_full Enrichment double-antibody sandwich indirect enzyme-linked immunosorbent assay that uses a specific monoclonal antibody for sensitive detection of Ralstonia solanacearum in asymptomatic potato tubers
title_fullStr Enrichment double-antibody sandwich indirect enzyme-linked immunosorbent assay that uses a specific monoclonal antibody for sensitive detection of Ralstonia solanacearum in asymptomatic potato tubers
title_full_unstemmed Enrichment double-antibody sandwich indirect enzyme-linked immunosorbent assay that uses a specific monoclonal antibody for sensitive detection of Ralstonia solanacearum in asymptomatic potato tubers
title_short Enrichment double-antibody sandwich indirect enzyme-linked immunosorbent assay that uses a specific monoclonal antibody for sensitive detection of Ralstonia solanacearum in asymptomatic potato tubers
title_sort enrichment double antibody sandwich indirect enzyme linked immunosorbent assay that uses a specific monoclonal antibody for sensitive detection of ralstonia solanacearum in asymptomatic potato tubers
url http://hdl.handle.net/20.500.11939/4978
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