Genetic variability and evolutionary dynamics of viruses of the family Closteroviridae.
RNA viruses have a great potential for genetic variation, rapid evolution and adaptation. Characterization of the genetic variation of viral populations provides relevant information on the processes involved in virus evolution and epidemiology and it is crucial for designing reliable diagnostic too...
| Main Authors: | , , |
|---|---|
| Format: | article |
| Language: | Inglés |
| Published: |
2017
|
| Online Access: | http://hdl.handle.net/20.500.11939/4448 |
| _version_ | 1855032122307248128 |
|---|---|
| author | Rubio, Luis Guerri, José Moreno, Pedro |
| author_browse | Guerri, José Moreno, Pedro Rubio, Luis |
| author_facet | Rubio, Luis Guerri, José Moreno, Pedro |
| author_sort | Rubio, Luis |
| collection | ReDivia |
| description | RNA viruses have a great potential for genetic variation, rapid evolution and adaptation. Characterization of the genetic variation of viral populations provides relevant information on the processes involved in virus evolution and epidemiology and it is crucial for designing reliable diagnostic tools and developing efficient and durable disease control strategies. Here we performed an updated analysis of sequences available in Genbank and reviewed present knowledge on the genetic variability and evolutionary processes of viruses of the family Closteroviridae. Several factors have shaped the genetic structure and diversity of closteroviruses. (I) A strong negative selection seems to be responsible for the high genetic stability in space and time for some viruses. (2) Long distance migration, probably by human transport of infected propagative plant material, have caused that genetically similar virus isolates are found in distant geographical regions. (3) Recombination between divergent sequence variants have generated new genotypes and plays an important role for the evolution of some viruses of the family Closteroviridae. (4) Interaction between virus strains or between different viruses in mixed infections may alter accumulation of certain strains. (5) Host change or virus transmission by insect vectors induced changes in the viral population structure due to positive selection of sequence variants with higher fitness for host-virus or vector-virus interaction (adaptation) or by genetic drift due to random selection of sequence variants during the population bottleneck associated to the transmission process. |
| format | article |
| id | ReDivia4448 |
| institution | Instituto Valenciano de Investigaciones Agrarias (IVIA) |
| language | Inglés |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| record_format | dspace |
| spelling | ReDivia44482025-04-25T14:43:33Z Genetic variability and evolutionary dynamics of viruses of the family Closteroviridae. Rubio, Luis Guerri, José Moreno, Pedro RNA viruses have a great potential for genetic variation, rapid evolution and adaptation. Characterization of the genetic variation of viral populations provides relevant information on the processes involved in virus evolution and epidemiology and it is crucial for designing reliable diagnostic tools and developing efficient and durable disease control strategies. Here we performed an updated analysis of sequences available in Genbank and reviewed present knowledge on the genetic variability and evolutionary processes of viruses of the family Closteroviridae. Several factors have shaped the genetic structure and diversity of closteroviruses. (I) A strong negative selection seems to be responsible for the high genetic stability in space and time for some viruses. (2) Long distance migration, probably by human transport of infected propagative plant material, have caused that genetically similar virus isolates are found in distant geographical regions. (3) Recombination between divergent sequence variants have generated new genotypes and plays an important role for the evolution of some viruses of the family Closteroviridae. (4) Interaction between virus strains or between different viruses in mixed infections may alter accumulation of certain strains. (5) Host change or virus transmission by insect vectors induced changes in the viral population structure due to positive selection of sequence variants with higher fitness for host-virus or vector-virus interaction (adaptation) or by genetic drift due to random selection of sequence variants during the population bottleneck associated to the transmission process. 2017-06-01T10:10:09Z 2017-06-01T10:10:09Z 2013 2013 article publishedVersion Rubio, L., Guerri, J., Moreno, P. (2013). Genetic variability and evolutionary dynamics of viruses of the family Closteroviridae.. Frontiers in microbiology, 4, 151-151. 1664-302X http://hdl.handle.net/20.500.11939/4448 http://hdl.handle.net/20.500.11939/4448 10.3389/fmicb.2013.00151 en openAccess Impreso |
| spellingShingle | Rubio, Luis Guerri, José Moreno, Pedro Genetic variability and evolutionary dynamics of viruses of the family Closteroviridae. |
| title | Genetic variability and evolutionary dynamics of viruses of the family Closteroviridae. |
| title_full | Genetic variability and evolutionary dynamics of viruses of the family Closteroviridae. |
| title_fullStr | Genetic variability and evolutionary dynamics of viruses of the family Closteroviridae. |
| title_full_unstemmed | Genetic variability and evolutionary dynamics of viruses of the family Closteroviridae. |
| title_short | Genetic variability and evolutionary dynamics of viruses of the family Closteroviridae. |
| title_sort | genetic variability and evolutionary dynamics of viruses of the family closteroviridae |
| url | http://hdl.handle.net/20.500.11939/4448 http://hdl.handle.net/20.500.11939/4448 |
| work_keys_str_mv | AT rubioluis geneticvariabilityandevolutionarydynamicsofvirusesofthefamilyclosteroviridae AT guerrijose geneticvariabilityandevolutionarydynamicsofvirusesofthefamilyclosteroviridae AT morenopedro geneticvariabilityandevolutionarydynamicsofvirusesofthefamilyclosteroviridae |