Role of Embryonic and Maternal Genotype on Prenatal Survival and Foetal Growth in Rabbit

Contents The aim of this work was to evaluate the influence of maternal and embryonic genotype on prenatal survival and foetal growth during pregnancy. Embryos were recovered at 48h of gestation from two different donor lines (R=46 and A=40) and transferred to nulliparous recipient does (26 R and 24...

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Autores principales: Naturil-Alfonso, C., Marco-Jiménez, Francisco, Jiménez-Trigos, E., Saenz-de-Juano, M. D., Viudes-De-Castro, María P., Lavara, R., Vicente, José Salvador
Formato: article
Lenguaje:Inglés
Publicado: 2017
Materias:
Acceso en línea:http://hdl.handle.net/20.500.11939/4201
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author Naturil-Alfonso, C.
Marco-Jiménez, Francisco
Jiménez-Trigos, E.
Saenz-de-Juano, M. D.
Viudes-De-Castro, María P.
Lavara, R.
Vicente, José Salvador
author_browse Jiménez-Trigos, E.
Lavara, R.
Marco-Jiménez, Francisco
Naturil-Alfonso, C.
Saenz-de-Juano, M. D.
Vicente, José Salvador
Viudes-De-Castro, María P.
author_facet Naturil-Alfonso, C.
Marco-Jiménez, Francisco
Jiménez-Trigos, E.
Saenz-de-Juano, M. D.
Viudes-De-Castro, María P.
Lavara, R.
Vicente, José Salvador
author_sort Naturil-Alfonso, C.
collection ReDivia
description Contents The aim of this work was to evaluate the influence of maternal and embryonic genotype on prenatal survival and foetal growth during pregnancy. Embryos were recovered at 48h of gestation from two different donor lines (R=46 and A=40) and transferred to nulliparous recipient does (26 R and 24 A). Each recipient doe received six embryos into one oviduct from line R, and six embryos form line A into the other. Laparoscopy was performed at Day 14 to determine implantation rate. Recipient females were slaughter at Days 14, 24 and 30 (12, 24, and 14, respectively) to determine the number of live foetuses and the weight of live foetuses, foetal placenta and maternal placenta. A transcriptome analysis was performed to search for differences between foetal placentas at Days 14 and 24 of development. Prenatal survival at Days 14, and 24 was affected by embryonic genotype and determined by maternal genotype at Day 30. Foetal weight at Day 14 was influenced by both genotypes, being the weight higher for group A/A (0.29 +/- 0.01g vs 0.19 +/- 0.01g, for group R/R). However, both genotypes were determinant for foetal placenta weight at Day 24, while those genotypes affected maternal placenta weight at Day 30. Nevertheless, no differences in foetal placenta at transcriptome level and progesterone and IGF-I plasma levels in recipient does were found. In conclusion, results indicate that the influence of embryo and maternal genotype on the prenatal survival and growth seems to be changing over gestation.
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spelling ReDivia42012025-04-25T14:42:32Z Role of Embryonic and Maternal Genotype on Prenatal Survival and Foetal Growth in Rabbit Naturil-Alfonso, C. Marco-Jiménez, Francisco Jiménez-Trigos, E. Saenz-de-Juano, M. D. Viudes-De-Castro, María P. Lavara, R. Vicente, José Salvador TRANSFERRED MOUSE EMBRYOS MESSENGER-RNA EXPRESSION UTERINE CAPACITY BODY-WEIGHT GENE-EXPRESSION LITTER SIZE IN-VIVO PLACENTAL DEVELOPMENT DIVERGENT SELECTION GESTATIONAL LOSSES Contents The aim of this work was to evaluate the influence of maternal and embryonic genotype on prenatal survival and foetal growth during pregnancy. Embryos were recovered at 48h of gestation from two different donor lines (R=46 and A=40) and transferred to nulliparous recipient does (26 R and 24 A). Each recipient doe received six embryos into one oviduct from line R, and six embryos form line A into the other. Laparoscopy was performed at Day 14 to determine implantation rate. Recipient females were slaughter at Days 14, 24 and 30 (12, 24, and 14, respectively) to determine the number of live foetuses and the weight of live foetuses, foetal placenta and maternal placenta. A transcriptome analysis was performed to search for differences between foetal placentas at Days 14 and 24 of development. Prenatal survival at Days 14, and 24 was affected by embryonic genotype and determined by maternal genotype at Day 30. Foetal weight at Day 14 was influenced by both genotypes, being the weight higher for group A/A (0.29 +/- 0.01g vs 0.19 +/- 0.01g, for group R/R). However, both genotypes were determinant for foetal placenta weight at Day 24, while those genotypes affected maternal placenta weight at Day 30. Nevertheless, no differences in foetal placenta at transcriptome level and progesterone and IGF-I plasma levels in recipient does were found. In conclusion, results indicate that the influence of embryo and maternal genotype on the prenatal survival and growth seems to be changing over gestation. 2017-06-01T10:09:34Z 2017-06-01T10:09:34Z 2015 APR article Naturil-Alfonso, C., Marco-Jimenez, F., Jimenez-Trigos, E., Saenz-de-J.o, M. D., Viudes-de-Castro, M.P., Lavara, R., Vicente, J.S. (2015). Role of Embryonic and Maternal Genotype on Prenatal Survival and Foetal Growth in Rabbit. Reproduction in Domestic Animals, 50(2), 312-320. 0936-6768 http://hdl.handle.net/20.500.11939/4201 10.1111/rda.12493 en openAccess Impreso
spellingShingle TRANSFERRED MOUSE EMBRYOS
MESSENGER-RNA EXPRESSION
UTERINE CAPACITY
BODY-WEIGHT
GENE-EXPRESSION
LITTER SIZE
IN-VIVO
PLACENTAL
DEVELOPMENT
DIVERGENT SELECTION
GESTATIONAL LOSSES
Naturil-Alfonso, C.
Marco-Jiménez, Francisco
Jiménez-Trigos, E.
Saenz-de-Juano, M. D.
Viudes-De-Castro, María P.
Lavara, R.
Vicente, José Salvador
Role of Embryonic and Maternal Genotype on Prenatal Survival and Foetal Growth in Rabbit
title Role of Embryonic and Maternal Genotype on Prenatal Survival and Foetal Growth in Rabbit
title_full Role of Embryonic and Maternal Genotype on Prenatal Survival and Foetal Growth in Rabbit
title_fullStr Role of Embryonic and Maternal Genotype on Prenatal Survival and Foetal Growth in Rabbit
title_full_unstemmed Role of Embryonic and Maternal Genotype on Prenatal Survival and Foetal Growth in Rabbit
title_short Role of Embryonic and Maternal Genotype on Prenatal Survival and Foetal Growth in Rabbit
title_sort role of embryonic and maternal genotype on prenatal survival and foetal growth in rabbit
topic TRANSFERRED MOUSE EMBRYOS
MESSENGER-RNA EXPRESSION
UTERINE CAPACITY
BODY-WEIGHT
GENE-EXPRESSION
LITTER SIZE
IN-VIVO
PLACENTAL
DEVELOPMENT
DIVERGENT SELECTION
GESTATIONAL LOSSES
url http://hdl.handle.net/20.500.11939/4201
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