Single nucleotide polymorphisms may explain the contrasting phenotypes of two variants of a multidrug-resistant Mycobacterium tuberculosis strain

Globally, about 4.5% of new tuberculosis (TB) cases are multi-drug-resistant (MDR), i.e. resistant to the two most powerful first-line anti-TB drugs. Indeed, 480,000 people developed MDR-TB in 2015 and 190,000 people died because of MDR-TB. The MDR Mycobacterium tuberculosis M family, which belongs...

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Bibliographic Details

Main Authors:	Bigi, María Mercedes, López, Beatriz, Blanco, Federico Carlos, Sasiain, María del Carmen, De La Barrera, Silvia Susana, Marti, Marcelo Adrián, Sosa, Ezequiel Jorge, Fernandez Do Porto, Darío Augusto, Ritacco, Viviana, Bigi, Fabiana, Soria, Marcelo Abel
Format:	Artículo
Language:	Inglés
Published:	2017
Subjects:	Mycobacterium tuberculosis Polimorfismo Nucleótidos Fenotipos Polymorphism Nucleotides Phenotypes
Online Access:	http://hdl.handle.net/20.500.12123/967 http://www.tuberculosisjournal.com/article/S1472-9792(16)30366-3/fulltext https://doi.org/10.1016/j.tube.2016.12.007