Two years of surveillance of influenza a virus infection in a swine herd. Results of virological, serological and pathological studies

Swine farms provide a dynamic environment for the evolution of influenza A viruses (IAVs). The present report shows the results of a surveillance effort of IAV infection in one commercial swine farm in Argentina. Two cross-sectional serological and virological studies (n = 480) were carried out in 2...

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Autores principales: Cappuccio, Javier Alejandro, Dibarbora, Marina, Lozada, María Inés, Quiroga, María Alejandra, Olivera, Valeria Soledad, Dangelo, Marta, Pérez, Estefanía Marisol, Barrales, Hernán, Perfumo, Carlos Juan, Pereda, Ariel Julian, Pérez, Daniel R.
Formato: Artículo
Lenguaje:Inglés
Publicado: 2017
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/937
http://ac.els-cdn.com/S0147957116301266/1-s2.0-S0147957116301266-main.pdf?_tid=b44ba944-7d29-11e7-9bec-00000aacb35d&acdnat=1502300553_83818f4df664af7495dfaf8fe5db90d9
https://doi.org/10.1016/j.cimid.2016.12.005
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author Cappuccio, Javier Alejandro
Dibarbora, Marina
Lozada, María Inés
Quiroga, María Alejandra
Olivera, Valeria Soledad
Dangelo, Marta
Pérez, Estefanía Marisol
Barrales, Hernán
Perfumo, Carlos Juan
Pereda, Ariel Julian
Pérez, Daniel R.
author_browse Barrales, Hernán
Cappuccio, Javier Alejandro
Dangelo, Marta
Dibarbora, Marina
Lozada, María Inés
Olivera, Valeria Soledad
Pereda, Ariel Julian
Perfumo, Carlos Juan
Pérez, Daniel R.
Pérez, Estefanía Marisol
Quiroga, María Alejandra
author_facet Cappuccio, Javier Alejandro
Dibarbora, Marina
Lozada, María Inés
Quiroga, María Alejandra
Olivera, Valeria Soledad
Dangelo, Marta
Pérez, Estefanía Marisol
Barrales, Hernán
Perfumo, Carlos Juan
Pereda, Ariel Julian
Pérez, Daniel R.
author_sort Cappuccio, Javier Alejandro
collection INTA Digital
description Swine farms provide a dynamic environment for the evolution of influenza A viruses (IAVs). The present report shows the results of a surveillance effort of IAV infection in one commercial swine farm in Argentina. Two cross-sectional serological and virological studies (n = 480) were carried out in 2011 and 2012. Virus shedding was detected in nasal samples from pigs from ages 7, 21 and 42-days old. More than 90% of sows and gilts but less than 40% of 21-days old piglets had antibodies against IAV. In addition, IAV was detected in 8/17 nasal swabs and 10/15 lung samples taken from necropsied pigs. A subset of these samples was further processed for virus isolation resulting in 6 viruses of the H1N2 subtype (ı2 cluster). Pathological studies revealed an association between suppurative bronchopneumonia and necrotizing bronchiolitis with IAV positive samples. Statistical analyses showed that the degree of lesions in bronchi, bronchiole, and alveoli was higher in lungs positive to IAV. The results of this study depict the relevance of continuing long-term active surveillance of IAV in swine populations to establish IAV evolution relevant to swine and humans.
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spelling INTA9372018-10-17T11:25:08Z Two years of surveillance of influenza a virus infection in a swine herd. Results of virological, serological and pathological studies Cappuccio, Javier Alejandro Dibarbora, Marina Lozada, María Inés Quiroga, María Alejandra Olivera, Valeria Soledad Dangelo, Marta Pérez, Estefanía Marisol Barrales, Hernán Perfumo, Carlos Juan Pereda, Ariel Julian Pérez, Daniel R. Cerdo Enfermedades de los Animales Hatos Virus de la Influenza Porcina Virología Serología Patología Swine Herds Swine influenzavirus Virology Serology Pathology Animal Diseases Porcinos Swine farms provide a dynamic environment for the evolution of influenza A viruses (IAVs). The present report shows the results of a surveillance effort of IAV infection in one commercial swine farm in Argentina. Two cross-sectional serological and virological studies (n = 480) were carried out in 2011 and 2012. Virus shedding was detected in nasal samples from pigs from ages 7, 21 and 42-days old. More than 90% of sows and gilts but less than 40% of 21-days old piglets had antibodies against IAV. In addition, IAV was detected in 8/17 nasal swabs and 10/15 lung samples taken from necropsied pigs. A subset of these samples was further processed for virus isolation resulting in 6 viruses of the H1N2 subtype (ı2 cluster). Pathological studies revealed an association between suppurative bronchopneumonia and necrotizing bronchiolitis with IAV positive samples. Statistical analyses showed that the degree of lesions in bronchi, bronchiole, and alveoli was higher in lungs positive to IAV. The results of this study depict the relevance of continuing long-term active surveillance of IAV in swine populations to establish IAV evolution relevant to swine and humans. Inst.de Virología Fil: Cappuccio, Javier Alejandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Dibarbora, Marina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Lozada, María Inés. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Departamento de Patología. Laboratorio de Patología Especial Veterinaria; Argentina Fil: Quiroga, María Alejandra. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Departamento de Patología. Laboratorio de Patología Especial Veterinaria; Argentina Fil: Olivera, Valeria Soledad. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina Fil: Dangelo, Marta. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina Fil: Pérez, Estefanía Marisol. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Departamento de Patología. Laboratorio de Patología Especial Veterinaria; Argentina Fil: Barrales, Hernán. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Departamento de Patología. Laboratorio de Patología Especial Veterinaria; Argentina Fil: Perfumo, Carlos Juan. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Departamento de Patología. Laboratorio de Patología Especial Veterinaria; Argentina Fil: Pereda, Ariel Julian. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina Fil: Pérez, Daniel R. University of Georgia. College of Veterinary Medicine. Poultry Diagnostic and Research Center; Estados Unidos 2017-08-09T17:08:23Z 2017-08-09T17:08:23Z 2017 info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/937 http://ac.els-cdn.com/S0147957116301266/1-s2.0-S0147957116301266-main.pdf?_tid=b44ba944-7d29-11e7-9bec-00000aacb35d&acdnat=1502300553_83818f4df664af7495dfaf8fe5db90d9 0147-9571 https://doi.org/10.1016/j.cimid.2016.12.005 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Comparative Immunology, Microbiology and Infectious Diseases 50 : 110-115
spellingShingle Cerdo
Enfermedades de los Animales
Hatos
Virus de la Influenza Porcina
Virología
Serología
Patología
Swine
Herds
Swine influenzavirus
Virology
Serology
Pathology
Animal Diseases
Porcinos
Cappuccio, Javier Alejandro
Dibarbora, Marina
Lozada, María Inés
Quiroga, María Alejandra
Olivera, Valeria Soledad
Dangelo, Marta
Pérez, Estefanía Marisol
Barrales, Hernán
Perfumo, Carlos Juan
Pereda, Ariel Julian
Pérez, Daniel R.
Two years of surveillance of influenza a virus infection in a swine herd. Results of virological, serological and pathological studies
title Two years of surveillance of influenza a virus infection in a swine herd. Results of virological, serological and pathological studies
title_full Two years of surveillance of influenza a virus infection in a swine herd. Results of virological, serological and pathological studies
title_fullStr Two years of surveillance of influenza a virus infection in a swine herd. Results of virological, serological and pathological studies
title_full_unstemmed Two years of surveillance of influenza a virus infection in a swine herd. Results of virological, serological and pathological studies
title_short Two years of surveillance of influenza a virus infection in a swine herd. Results of virological, serological and pathological studies
title_sort two years of surveillance of influenza a virus infection in a swine herd results of virological serological and pathological studies
topic Cerdo
Enfermedades de los Animales
Hatos
Virus de la Influenza Porcina
Virología
Serología
Patología
Swine
Herds
Swine influenzavirus
Virology
Serology
Pathology
Animal Diseases
Porcinos
url http://hdl.handle.net/20.500.12123/937
http://ac.els-cdn.com/S0147957116301266/1-s2.0-S0147957116301266-main.pdf?_tid=b44ba944-7d29-11e7-9bec-00000aacb35d&acdnat=1502300553_83818f4df664af7495dfaf8fe5db90d9
https://doi.org/10.1016/j.cimid.2016.12.005
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