Changes in hematological, biochemical, and blood gases prameters in response to progressive inclusion of nitrate in the diet of Holstein calves
Background and Aim: Nitrate (NO3-) reduces enteric methane emissions and could be a source of non-protein nitrogen in ruminant feeds. Nonetheless, it has a potential toxic effect that could compromise animal health and production. The purpose of this study was to determine the effects of progressive...
| Autores principales: | , , , , , , , , , |
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| Formato: | info:ar-repo/semantics/artículo |
| Lenguaje: | Inglés |
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Veterinary World Publisher
2021
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/9104 http://www.veterinaryworld.org/Vol.14/January-2021/8.html https://www.doi.org/10.14202/vetworld.2021.61-69 |
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| author | Ortiz Chura, Abimael Marcoppido, Gisela Ariana Gere, José Ignacio Depetris, Gustavo Stefañuk Bahamonde, Francisco José Trangoni, Marcos David Cravero, Silvio Lorenzo Pedro Faverin, Claudia Cataldi, Angel Adrian Ceron Cucchi, Maria Esperanza |
| author_browse | Cataldi, Angel Adrian Ceron Cucchi, Maria Esperanza Cravero, Silvio Lorenzo Pedro Depetris, Gustavo Faverin, Claudia Gere, José Ignacio Marcoppido, Gisela Ariana Ortiz Chura, Abimael Stefañuk Bahamonde, Francisco José Trangoni, Marcos David |
| author_facet | Ortiz Chura, Abimael Marcoppido, Gisela Ariana Gere, José Ignacio Depetris, Gustavo Stefañuk Bahamonde, Francisco José Trangoni, Marcos David Cravero, Silvio Lorenzo Pedro Faverin, Claudia Cataldi, Angel Adrian Ceron Cucchi, Maria Esperanza |
| author_sort | Ortiz Chura, Abimael |
| collection | INTA Digital |
| description | Background and Aim: Nitrate (NO3-) reduces enteric methane emissions and could be a source of non-protein nitrogen in ruminant feeds. Nonetheless, it has a potential toxic effect that could compromise animal health and production. The purpose of this study was to determine the effects of progressive inclusion of NO3- in the diet on the hematological, biochemical, and blood gases parameters, in turn, the effects on feed intake and live weight gain (LWG) in Holstein calves.
Materials and Methods: Eighteen Holstein heifers and steers (nine animals/treatment) were maintained in individual pens for 45 days. Animals were randomly allocated to either a control or nitrate diet (ND) (containing 15 g of NO3-/kg of dry matter [DM]). The biochemical parameters and blood gases were analyzed only in the NO3- group on days: -1, 1, 7, 13, 19, and 25 corresponding to 0, 20, 40, 60, 80, and 100% of the total inclusion of NO3- in the diet, respectively. In addition, DM intake (DMI) and LWG were evaluated among dietary treatments.
Results: Feeding the ND did not influence DMI or LWG (p>0.05). Methemoglobin (MetHb) and deoxyhemoglobin increased according to the NO3- concentrations in the diet (p<0.05), while an opposite effect was observed for oxyhemoglobin and carboxyhemoglobin (p<0.05). Hematocrit levels decreased (p<0.05), while albumin, alanine aminotransferase, and gamma-glutamyl transpeptidase concentrations were not modified (p>0.05). However, glucose, urea, aspartate aminotransferase (AST), and retinol concentrations increased (p<0.05) according to the NO3- concentrations in the diet. |
| format | info:ar-repo/semantics/artículo |
| id | INTA9104 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Veterinary World Publisher |
| publisherStr | Veterinary World Publisher |
| record_format | dspace |
| spelling | INTA91042025-07-30T12:31:15Z Changes in hematological, biochemical, and blood gases prameters in response to progressive inclusion of nitrate in the diet of Holstein calves Ortiz Chura, Abimael Marcoppido, Gisela Ariana Gere, José Ignacio Depetris, Gustavo Stefañuk Bahamonde, Francisco José Trangoni, Marcos David Cravero, Silvio Lorenzo Pedro Faverin, Claudia Cataldi, Angel Adrian Ceron Cucchi, Maria Esperanza Liver Function Tests Nitrates Diet Calves Toxicity Pruebas de Función Hepática Nitratos Dieta Ternero Toxicidad Raza Holstein Background and Aim: Nitrate (NO3-) reduces enteric methane emissions and could be a source of non-protein nitrogen in ruminant feeds. Nonetheless, it has a potential toxic effect that could compromise animal health and production. The purpose of this study was to determine the effects of progressive inclusion of NO3- in the diet on the hematological, biochemical, and blood gases parameters, in turn, the effects on feed intake and live weight gain (LWG) in Holstein calves. Materials and Methods: Eighteen Holstein heifers and steers (nine animals/treatment) were maintained in individual pens for 45 days. Animals were randomly allocated to either a control or nitrate diet (ND) (containing 15 g of NO3-/kg of dry matter [DM]). The biochemical parameters and blood gases were analyzed only in the NO3- group on days: -1, 1, 7, 13, 19, and 25 corresponding to 0, 20, 40, 60, 80, and 100% of the total inclusion of NO3- in the diet, respectively. In addition, DM intake (DMI) and LWG were evaluated among dietary treatments. Results: Feeding the ND did not influence DMI or LWG (p>0.05). Methemoglobin (MetHb) and deoxyhemoglobin increased according to the NO3- concentrations in the diet (p<0.05), while an opposite effect was observed for oxyhemoglobin and carboxyhemoglobin (p<0.05). Hematocrit levels decreased (p<0.05), while albumin, alanine aminotransferase, and gamma-glutamyl transpeptidase concentrations were not modified (p>0.05). However, glucose, urea, aspartate aminotransferase (AST), and retinol concentrations increased (p<0.05) according to the NO3- concentrations in the diet. Instituto de Patobiología Fil: Ortiz Chura, Abimael. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina Fil: Ortiz Chura, Abimael. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Marcoppido, Gisela Ariana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina Fil: Marcoppido, Gisela Ariana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Gere, José. Universidad Tecnológica Nacional. División Investigación y Desarrollo de Ingenierías; Argentina Fil: Gere, José. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Depetris, Gustavo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina Fil: Stefañuk Bahamonte, Francisco José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina Fil: Trangoni, Marcos David. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular. Argentina Fil: Trangoni, Marcos David. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Cravero, Silvio Lorenzo Pedro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina Fil: Cravero, Silvio Lorenzo Pedro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Faverin, Claudia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina Fil: Cataldi, Angel Adrian. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina Fil: Cataldi, Angel Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Ceron Cucchi, Maria Esperanza. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina Fil: Ceron Cucchi, Maria Esperanza. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina 2021-04-16T11:00:15Z 2021-04-16T11:00:15Z 2021-01 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/9104 http://www.veterinaryworld.org/Vol.14/January-2021/8.html 2231-0916 0972-8988 https://www.doi.org/10.14202/vetworld.2021.61-69 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Veterinary World Publisher Veterinary World 14 (1) : 61-69 (Enero 2021) |
| spellingShingle | Liver Function Tests Nitrates Diet Calves Toxicity Pruebas de Función Hepática Nitratos Dieta Ternero Toxicidad Raza Holstein Ortiz Chura, Abimael Marcoppido, Gisela Ariana Gere, José Ignacio Depetris, Gustavo Stefañuk Bahamonde, Francisco José Trangoni, Marcos David Cravero, Silvio Lorenzo Pedro Faverin, Claudia Cataldi, Angel Adrian Ceron Cucchi, Maria Esperanza Changes in hematological, biochemical, and blood gases prameters in response to progressive inclusion of nitrate in the diet of Holstein calves |
| title | Changes in hematological, biochemical, and blood gases prameters in response to progressive inclusion of nitrate in the diet of Holstein calves |
| title_full | Changes in hematological, biochemical, and blood gases prameters in response to progressive inclusion of nitrate in the diet of Holstein calves |
| title_fullStr | Changes in hematological, biochemical, and blood gases prameters in response to progressive inclusion of nitrate in the diet of Holstein calves |
| title_full_unstemmed | Changes in hematological, biochemical, and blood gases prameters in response to progressive inclusion of nitrate in the diet of Holstein calves |
| title_short | Changes in hematological, biochemical, and blood gases prameters in response to progressive inclusion of nitrate in the diet of Holstein calves |
| title_sort | changes in hematological biochemical and blood gases prameters in response to progressive inclusion of nitrate in the diet of holstein calves |
| topic | Liver Function Tests Nitrates Diet Calves Toxicity Pruebas de Función Hepática Nitratos Dieta Ternero Toxicidad Raza Holstein |
| url | http://hdl.handle.net/20.500.12123/9104 http://www.veterinaryworld.org/Vol.14/January-2021/8.html https://www.doi.org/10.14202/vetworld.2021.61-69 |
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