Antimicrobial resistance of Staphylococcus aureus isolated from bovine mastitis: Systematic review and meta-analysis
Staphylococcus aureus, one of the main contagious mastitis pathogens worldwide, is characterized for causing chronic intramammary infections that respond poorly to antimicrobial therapy, disseminating within the herd leading to high economic losses. The aim of this study was to determine the prevale...
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| Format: | Artículo |
| Language: | Inglés |
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Elsevier
2021
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| Online Access: | http://hdl.handle.net/20.500.12123/8815 https://www.sciencedirect.com/science/article/abs/pii/S0167587721000052 https://doi.org/10.1016/j.prevetmed.2021.105261 |
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| author | Molineri, Ana Ines Camussone, Cecilia Zbrun, María Virginia Suarez Archilla, Guillermo Cristiani, Mariana Neder, Veronica Elizabeth Calvinho, Luis Fernando Signorini Porchiett, Marcelo Lisandro |
| author_browse | Calvinho, Luis Fernando Camussone, Cecilia Cristiani, Mariana Molineri, Ana Ines Neder, Veronica Elizabeth Signorini Porchiett, Marcelo Lisandro Suarez Archilla, Guillermo Zbrun, María Virginia |
| author_facet | Molineri, Ana Ines Camussone, Cecilia Zbrun, María Virginia Suarez Archilla, Guillermo Cristiani, Mariana Neder, Veronica Elizabeth Calvinho, Luis Fernando Signorini Porchiett, Marcelo Lisandro |
| author_sort | Molineri, Ana Ines |
| collection | INTA Digital |
| description | Staphylococcus aureus, one of the main contagious mastitis pathogens worldwide, is characterized for causing chronic intramammary infections that respond poorly to antimicrobial therapy, disseminating within the herd leading to high economic losses. The aim of this study was to determine the prevalence of phenotypic resistance to antimicrobial agents among S. aureus collected worldwide in the context of bovine intramammary infections between the years 1969−2020. A systematic review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). One hundred and fifty-five articles were eligible for quantitative review. Most of studies included in this meta-analysis were from Europe (88), followed by Asia (56), Latin America (39), Africa (32), North America (26), and Oceania (8). The highest overall prevalence of resistant S. aureus was against penicillin (pestimate 0.451, CI95 % 0.415−0.487), followed by clindamycin, erythromycin, and gentamycin (p-estimate = 0.149, 0.085, and 0.069, respectively). Ceftiofur and cephalotin presented the lowest overall prevalence of antimicrobial resistance (AMR, p-estimate = 0.020 and 0.015, respectively). The AMR to almost all the antimicrobials evaluated presented an increasing pattern over time, more apparent from 2009 onwards. The antimicrobials with a higher increase in their AMR prevalence over time were clindamycin, gentamycin, and oxacillin. Africa, Asia and Latin America were the continents with higher AMR to most compounds included in this study. No differences in AMR were detected regarding the clinical origin of the isolates (subclinical vs clinical mastitis) for almost all antibiotics evaluated. Differences in the method for testing AMR (disc diffusion method vs minimum inhibitory concentration) and type of study design for monitoring AMR were detected underscoring the importance of these variables as critical factors to enable comparisons for evaluating emergence of AMR. |
| format | Artículo |
| id | INTA8815 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | INTA88152021-03-04T14:50:03Z Antimicrobial resistance of Staphylococcus aureus isolated from bovine mastitis: Systematic review and meta-analysis Molineri, Ana Ines Camussone, Cecilia Zbrun, María Virginia Suarez Archilla, Guillermo Cristiani, Mariana Neder, Veronica Elizabeth Calvinho, Luis Fernando Signorini Porchiett, Marcelo Lisandro Resistencia a los Antimicrobianos Staphylococcus aureus Enfermedades de los Animales Ganado Bovino Mastítis Bovina Antimicrobial Resistance Animal Diseases Cattle Bovine Mastitis Staphylococcus aureus, one of the main contagious mastitis pathogens worldwide, is characterized for causing chronic intramammary infections that respond poorly to antimicrobial therapy, disseminating within the herd leading to high economic losses. The aim of this study was to determine the prevalence of phenotypic resistance to antimicrobial agents among S. aureus collected worldwide in the context of bovine intramammary infections between the years 1969−2020. A systematic review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). One hundred and fifty-five articles were eligible for quantitative review. Most of studies included in this meta-analysis were from Europe (88), followed by Asia (56), Latin America (39), Africa (32), North America (26), and Oceania (8). The highest overall prevalence of resistant S. aureus was against penicillin (pestimate 0.451, CI95 % 0.415−0.487), followed by clindamycin, erythromycin, and gentamycin (p-estimate = 0.149, 0.085, and 0.069, respectively). Ceftiofur and cephalotin presented the lowest overall prevalence of antimicrobial resistance (AMR, p-estimate = 0.020 and 0.015, respectively). The AMR to almost all the antimicrobials evaluated presented an increasing pattern over time, more apparent from 2009 onwards. The antimicrobials with a higher increase in their AMR prevalence over time were clindamycin, gentamycin, and oxacillin. Africa, Asia and Latin America were the continents with higher AMR to most compounds included in this study. No differences in AMR were detected regarding the clinical origin of the isolates (subclinical vs clinical mastitis) for almost all antibiotics evaluated. Differences in the method for testing AMR (disc diffusion method vs minimum inhibitory concentration) and type of study design for monitoring AMR were detected underscoring the importance of these variables as critical factors to enable comparisons for evaluating emergence of AMR. EEA Rafaela Fil: Molineri, Ana Ines. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Camussone, Cecilia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fil: Zbrun, María Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina. Fil: Suarez Archilla, Guillermo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Cristiani, Mariana. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Neder, Veronica Elizabeth. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Calvinho, Luis Fernando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. 2021-03-04T14:46:04Z 2021-03-04T14:46:04Z 2021-03 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/8815 https://www.sciencedirect.com/science/article/abs/pii/S0167587721000052 0167-5877 https://doi.org/10.1016/j.prevetmed.2021.105261 eng info:eu-repo/semantics/restrictedAccess application/pdf Elsevier Preventive Veterinary Medicine 188 : 105261 (March 2021) |
| spellingShingle | Resistencia a los Antimicrobianos Staphylococcus aureus Enfermedades de los Animales Ganado Bovino Mastítis Bovina Antimicrobial Resistance Animal Diseases Cattle Bovine Mastitis Molineri, Ana Ines Camussone, Cecilia Zbrun, María Virginia Suarez Archilla, Guillermo Cristiani, Mariana Neder, Veronica Elizabeth Calvinho, Luis Fernando Signorini Porchiett, Marcelo Lisandro Antimicrobial resistance of Staphylococcus aureus isolated from bovine mastitis: Systematic review and meta-analysis |
| title | Antimicrobial resistance of Staphylococcus aureus isolated from bovine mastitis: Systematic review and meta-analysis |
| title_full | Antimicrobial resistance of Staphylococcus aureus isolated from bovine mastitis: Systematic review and meta-analysis |
| title_fullStr | Antimicrobial resistance of Staphylococcus aureus isolated from bovine mastitis: Systematic review and meta-analysis |
| title_full_unstemmed | Antimicrobial resistance of Staphylococcus aureus isolated from bovine mastitis: Systematic review and meta-analysis |
| title_short | Antimicrobial resistance of Staphylococcus aureus isolated from bovine mastitis: Systematic review and meta-analysis |
| title_sort | antimicrobial resistance of staphylococcus aureus isolated from bovine mastitis systematic review and meta analysis |
| topic | Resistencia a los Antimicrobianos Staphylococcus aureus Enfermedades de los Animales Ganado Bovino Mastítis Bovina Antimicrobial Resistance Animal Diseases Cattle Bovine Mastitis |
| url | http://hdl.handle.net/20.500.12123/8815 https://www.sciencedirect.com/science/article/abs/pii/S0167587721000052 https://doi.org/10.1016/j.prevetmed.2021.105261 |
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