IL-12 DNA Displays efficient adjuvant effects improving immunogenicity of Ag85A in DNA prime/MVA boost immunizations
Mycobacterium tuberculosis (Mtb) infection is one of the leading causes of death worldwide. The Modified Vaccinia Ankara (MVA) vaccine vector expressing the mycobacterial antigen 85A (MVA85A) was demonstrated to be safe, although it did not improve BCG efficacy, denoting the need to search for impro...
| Main Authors: | , , , , , , , |
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| Format: | Artículo |
| Language: | Inglés |
| Published: |
Frontiers Media
2021
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12123/8630 https://www.frontiersin.org/articles/10.3389/fcimb.2020.581812/full https://doi.org/10.3389/fcimb.2020.581812 |
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