Wild pigs (Sus scrofa) population as reservoirs for deleterious mutations in the RYR1 gene associated with Porcine Stress Syndrome
Porcine Stress Syndrome (PSS) is a disorder codified by the ryanodine receptor 1 gene (RYR1) and affects both animal welfare and the quality of the meat product. As a consequence, individuals with this syndrome generate great worldwide economic losses in the porcine industry. In Argentina, the Bueno...
| Autores principales: | , , , , , , , |
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| Formato: | info:ar-repo/semantics/artículo |
| Lenguaje: | Inglés |
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Elsevier
2020
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/8453 https://www.sciencedirect.com/science/article/pii/S2451943X20300739 https://doi.org/10.1016/j.vas.2020.100160 |
| _version_ | 1855036037947981824 |
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| author | Acosta, Diana Belén Español, Laureano Ángel Figueroa, Carlos Ezequiel Marini, Sebastián José Mac Allister, Matías Exequiel Carpinetti, Bruno Nicolás Fernández, Gabriela Paula Merino, Mariano Lisandro |
| author_browse | Acosta, Diana Belén Carpinetti, Bruno Nicolás Español, Laureano Ángel Fernández, Gabriela Paula Figueroa, Carlos Ezequiel Mac Allister, Matías Exequiel Marini, Sebastián José Merino, Mariano Lisandro |
| author_facet | Acosta, Diana Belén Español, Laureano Ángel Figueroa, Carlos Ezequiel Marini, Sebastián José Mac Allister, Matías Exequiel Carpinetti, Bruno Nicolás Fernández, Gabriela Paula Merino, Mariano Lisandro |
| author_sort | Acosta, Diana Belén |
| collection | INTA Digital |
| description | Porcine Stress Syndrome (PSS) is a disorder codified by the ryanodine receptor 1 gene (RYR1) and affects both animal welfare and the quality of the meat product. As a consequence, individuals with this syndrome generate great worldwide economic losses in the porcine industry. In Argentina, the Buenos Aires Province is the most involved on this activity, and productions are to be in open field with a higher frequency of pigs with diverse pathologies. On the other hand, the biggest and oldest wild pigs population is located on the Atlantic coast of Buenos Aires Province, which presents a continuous bidirectional flow of individuals with the productive areas nearby. The aim of this study is to detect the presence of the RYR1 deleterious allele in the wild population from the Atlantic coast of Buenos Aires, in order to evaluate its possible role as a genetic reservoir for said allele. For this purpose, 106 wild pigs from 28 sites were studied, finding a 6.6% of carrier individuals, indicating that the wild population is not free of this allele. This constitutes the first analysis to detect the presence of the RYR1 deleterious allele, associated to the PSS in wild pigs from Argentina, being one of the few studies to report it worldwide and suggesting wild pigs populations to be a possible genetic reservoir for this disease. |
| format | info:ar-repo/semantics/artículo |
| id | INTA8453 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | INTA84532024-08-19T13:58:53Z Wild pigs (Sus scrofa) population as reservoirs for deleterious mutations in the RYR1 gene associated with Porcine Stress Syndrome Acosta, Diana Belén Español, Laureano Ángel Figueroa, Carlos Ezequiel Marini, Sebastián José Mac Allister, Matías Exequiel Carpinetti, Bruno Nicolás Fernández, Gabriela Paula Merino, Mariano Lisandro Sus scrofa Jabalí Genética Enfermedades de los Animales Síndrome del Estrés Porcino Conservación de Recursos Genéticos Wild Boar Genetics Genes Animal Diseases Porcine Stress Syndrome Genetic Resources Conservation Porcine Stress Syndrome (PSS) is a disorder codified by the ryanodine receptor 1 gene (RYR1) and affects both animal welfare and the quality of the meat product. As a consequence, individuals with this syndrome generate great worldwide economic losses in the porcine industry. In Argentina, the Buenos Aires Province is the most involved on this activity, and productions are to be in open field with a higher frequency of pigs with diverse pathologies. On the other hand, the biggest and oldest wild pigs population is located on the Atlantic coast of Buenos Aires Province, which presents a continuous bidirectional flow of individuals with the productive areas nearby. The aim of this study is to detect the presence of the RYR1 deleterious allele in the wild population from the Atlantic coast of Buenos Aires, in order to evaluate its possible role as a genetic reservoir for said allele. For this purpose, 106 wild pigs from 28 sites were studied, finding a 6.6% of carrier individuals, indicating that the wild population is not free of this allele. This constitutes the first analysis to detect the presence of the RYR1 deleterious allele, associated to the PSS in wild pigs from Argentina, being one of the few studies to report it worldwide and suggesting wild pigs populations to be a possible genetic reservoir for this disease. EEA Marcos Juárez Fil: Acosta, Diana Belén. Universidad Nacional del Noroeste de la Provincia de Buenos Aires. Centro de Bioinvestigaciones; Argentina. Universidad Nacional del Noroeste de la Provincia de Buenos Aires. Centro de Investigaciones y Transferencia del Noroeste de la Provincia de Buenos Aires. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia del Noroeste de la Provincia de Buenos Aires; Argentina Fil: Español, Laureano Ángel. Universidad Nacional del Noroeste de la Provincia de Buenos Aires. Centro de Investigaciones Básicas y Aplicada; Argentina. Universidad Nacional del Noroeste de la Provincia de Buenos Aires. Centro de Investigaciones y Transferencia del Noroeste de la Provincia de Buenos Aires. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia del Noroeste de la Provincia de Buenos Aires; Argentina Fil: Figueroa, Carlos Ezequiel. Universidad Nacional del Noroeste de la Provincia de Buenos Aires. Centro de Bioinvestigaciones; Argentina. Universidad Nacional del Noroeste de la Provincia de Buenos Aires. Centro de Investigaciones y Transferencia del Noroeste de la Provincia de Buenos Aires. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia del Noroeste de la Provincia de Buenos Aires; Argentina Fil: Marini, Sebastián José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina Fil: Mac Allister, Matías Exequiel. Universidad Nacional del Noroeste de la Provincia de Buenos Aires. Centro de Bioinvestigaciones; Argentina. Universidad Nacional del Noroeste de la Provincia de Buenos Aires. Centro de Investigaciones y Transferencia del Noroeste de la Provincia de Buenos Aires. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia del Noroeste de la Provincia de Buenos Aires; Argentina Fil: Carpinetti, Bruno Nicolás. Universidad Nacional Arturo Jauretche. Instituto de Ciencias Sociales y Administración. Gestión Ambiental/Ecología; Argentina Fil: Fernández, Gabriela Paula. Universidad Nacional del Noroeste de la Provincia de Buenos Aires. Centro de Bioinvestigaciones; Argentina. Fil: Merino, Mariano Lisandro. Universidad Nacional del Noroeste de la Provincia de Buenos Aires. Centro de Bioinvestigaciones; Argentina. Gobierno de la Provincia de Buenos Aires. Comisión de Investigaciones Científicas; Argentina 2020-12-18T11:43:55Z 2020-12-18T11:43:55Z 2020-12 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion http://hdl.handle.net/20.500.12123/8453 https://www.sciencedirect.com/science/article/pii/S2451943X20300739 2451-943X https://doi.org/10.1016/j.vas.2020.100160 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Elsevier Veterinary and Animal Science : 100160 (Available online 14 December 2020) |
| spellingShingle | Sus scrofa Jabalí Genética Enfermedades de los Animales Síndrome del Estrés Porcino Conservación de Recursos Genéticos Wild Boar Genetics Genes Animal Diseases Porcine Stress Syndrome Genetic Resources Conservation Acosta, Diana Belén Español, Laureano Ángel Figueroa, Carlos Ezequiel Marini, Sebastián José Mac Allister, Matías Exequiel Carpinetti, Bruno Nicolás Fernández, Gabriela Paula Merino, Mariano Lisandro Wild pigs (Sus scrofa) population as reservoirs for deleterious mutations in the RYR1 gene associated with Porcine Stress Syndrome |
| title | Wild pigs (Sus scrofa) population as reservoirs for deleterious mutations in the RYR1 gene associated with Porcine Stress Syndrome |
| title_full | Wild pigs (Sus scrofa) population as reservoirs for deleterious mutations in the RYR1 gene associated with Porcine Stress Syndrome |
| title_fullStr | Wild pigs (Sus scrofa) population as reservoirs for deleterious mutations in the RYR1 gene associated with Porcine Stress Syndrome |
| title_full_unstemmed | Wild pigs (Sus scrofa) population as reservoirs for deleterious mutations in the RYR1 gene associated with Porcine Stress Syndrome |
| title_short | Wild pigs (Sus scrofa) population as reservoirs for deleterious mutations in the RYR1 gene associated with Porcine Stress Syndrome |
| title_sort | wild pigs sus scrofa population as reservoirs for deleterious mutations in the ryr1 gene associated with porcine stress syndrome |
| topic | Sus scrofa Jabalí Genética Enfermedades de los Animales Síndrome del Estrés Porcino Conservación de Recursos Genéticos Wild Boar Genetics Genes Animal Diseases Porcine Stress Syndrome Genetic Resources Conservation |
| url | http://hdl.handle.net/20.500.12123/8453 https://www.sciencedirect.com/science/article/pii/S2451943X20300739 https://doi.org/10.1016/j.vas.2020.100160 |
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