pBAR–H3.2, a native-optimized binary vector to bypass transgene silencing in alfalfa

Alfalfa is the main forage worldwide due to its high biomass production, excellent nutritional qualities and adaptation to a wide range of environments (Singer et al. 2018). Besides, due to its ability to grow without nitrogen fertilizers derived from fossil fuels and conditions of long-duration per...

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Main Authors: Pascuan, Cecilia Gabriela, Bottero, Ana Emilia, Kapros, Tamas, Ayub, Nicolás Daniel, Soto, Gabriela Cynthia
Format: info:ar-repo/semantics/artículo
Language:Inglés
Published: Springer 2020
Subjects:
Online Access:http://hdl.handle.net/20.500.12123/7732
https://link.springer.com/article/10.1007/s00299-020-02521-3
https://doi.org/10.1007/s00299-020-02521-3
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author Pascuan, Cecilia Gabriela
Bottero, Ana Emilia
Kapros, Tamas
Ayub, Nicolás Daniel
Soto, Gabriela Cynthia
author_browse Ayub, Nicolás Daniel
Bottero, Ana Emilia
Kapros, Tamas
Pascuan, Cecilia Gabriela
Soto, Gabriela Cynthia
author_facet Pascuan, Cecilia Gabriela
Bottero, Ana Emilia
Kapros, Tamas
Ayub, Nicolás Daniel
Soto, Gabriela Cynthia
author_sort Pascuan, Cecilia Gabriela
collection INTA Digital
description Alfalfa is the main forage worldwide due to its high biomass production, excellent nutritional qualities and adaptation to a wide range of environments (Singer et al. 2018). Besides, due to its ability to grow without nitrogen fertilizers derived from fossil fuels and conditions of long-duration perennial crop, alfalfa is a natural candidate for large production of renewable raw materials and vaccines at extremely low cost (Aguirreburualde et al. 2013; Saruul et al. 2002). However, the potential impact of alfalfa in agroindustrial processes is limited by strong transgene silencing. In the absence of genetic tools to bypass this constraint, the identification of alfalfa events with suitable transgene expression for commercial uses (e.g., high expression of transgenic traits) requires the production and analysis of a large number (e.g., 2000–3000) of transgenic events (Barros et al. 2019; Jozefkowicz et al. 2018; McCaslin et al. 2002). Naturally, this is an expensive empirical approach restricted to projects with high budget.
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
publishDate 2020
publishDateRange 2020
publishDateSort 2020
publisher Springer
publisherStr Springer
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spelling INTA77322020-08-18T14:57:17Z pBAR–H3.2, a native-optimized binary vector to bypass transgene silencing in alfalfa Pascuan, Cecilia Gabriela Bottero, Ana Emilia Kapros, Tamas Ayub, Nicolás Daniel Soto, Gabriela Cynthia Medicago sativa Genética Plantas Transgénicas Vectores Genetics Transgenic Plants Vectors Alfalfa Lucerne Alfalfa is the main forage worldwide due to its high biomass production, excellent nutritional qualities and adaptation to a wide range of environments (Singer et al. 2018). Besides, due to its ability to grow without nitrogen fertilizers derived from fossil fuels and conditions of long-duration perennial crop, alfalfa is a natural candidate for large production of renewable raw materials and vaccines at extremely low cost (Aguirreburualde et al. 2013; Saruul et al. 2002). However, the potential impact of alfalfa in agroindustrial processes is limited by strong transgene silencing. In the absence of genetic tools to bypass this constraint, the identification of alfalfa events with suitable transgene expression for commercial uses (e.g., high expression of transgenic traits) requires the production and analysis of a large number (e.g., 2000–3000) of transgenic events (Barros et al. 2019; Jozefkowicz et al. 2018; McCaslin et al. 2002). Naturally, this is an expensive empirical approach restricted to projects with high budget. Instituto de Genética Fil: Pascuan, Cecilia Gabriela. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Genética e Instituto de Biotecnología; Argentina Fil: Bottero, Ana Emilia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Genética e Instituto de Biotecnología; Argentina Fil: Kapros, Tamas. University of Missouri-Kansas City. School of Biological and Chemical Sciences; Estados Unidos Fil: Ayub, Nicolás Daniel. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Genética e Instituto de Biotecnología; Argentina Fil: Soto, Gabriela Cynthia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Genética e Instituto de Biotecnología; Argentina 2020-08-18T14:50:48Z 2020-08-18T14:50:48Z 2020-03 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/7732 https://link.springer.com/article/10.1007/s00299-020-02521-3 0721-7714 1432-203X https://doi.org/10.1007/s00299-020-02521-3 eng info:eu-repo/semantics/restrictedAccess application/pdf Springer Plant Cell Reports 39 : 683–685 (2020)
spellingShingle Medicago sativa
Genética
Plantas Transgénicas
Vectores
Genetics
Transgenic Plants
Vectors
Alfalfa
Lucerne
Pascuan, Cecilia Gabriela
Bottero, Ana Emilia
Kapros, Tamas
Ayub, Nicolás Daniel
Soto, Gabriela Cynthia
pBAR–H3.2, a native-optimized binary vector to bypass transgene silencing in alfalfa
title pBAR–H3.2, a native-optimized binary vector to bypass transgene silencing in alfalfa
title_full pBAR–H3.2, a native-optimized binary vector to bypass transgene silencing in alfalfa
title_fullStr pBAR–H3.2, a native-optimized binary vector to bypass transgene silencing in alfalfa
title_full_unstemmed pBAR–H3.2, a native-optimized binary vector to bypass transgene silencing in alfalfa
title_short pBAR–H3.2, a native-optimized binary vector to bypass transgene silencing in alfalfa
title_sort pbar h3 2 a native optimized binary vector to bypass transgene silencing in alfalfa
topic Medicago sativa
Genética
Plantas Transgénicas
Vectores
Genetics
Transgenic Plants
Vectors
Alfalfa
Lucerne
url http://hdl.handle.net/20.500.12123/7732
https://link.springer.com/article/10.1007/s00299-020-02521-3
https://doi.org/10.1007/s00299-020-02521-3
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