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Distinctive features of bovine alphaherpesvirus types 1 and 5 and the virus-host interactions that might influence clinical outcomes

Bovine herpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are two closely related alpha-herpesviruses. BoHV-1 causes several syndromes in cattle, including respiratory disease and sporadic cases of encephalitis, whereas BoHV-5 is responsible for meningoencephalitis in calves. Although both viruses are neur...

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Main Authors: Marin, Maia Solange, Burucua, María Mercedes, Resentti, Daniel, Rosales, Juan José, Odeon, Anselmo Carlos, Pérez, Sandra
Format: info:ar-repo/semantics/artículo
Language:Inglés
Published: Springer 2020
Subjects:
Herpes Virus Bovino
Patogénesis
Sistema Respiratorio
Meningoencefalitis
Bovine Herpesvirus
Pathogenesis
Respiratory System
Meningoencephalitis
Online Access:http://hdl.handle.net/20.500.12123/7358
https://link.springer.com/article/10.1007/s00705-019-04494-5
https://doi.org/10.1007/s00705-019-04494-5
Summary:Bovine herpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are two closely related alpha-herpesviruses. BoHV-1 causes several syndromes in cattle, including respiratory disease and sporadic cases of encephalitis, whereas BoHV-5 is responsible for meningoencephalitis in calves. Although both viruses are neurotropic they differ in their neuropathogenic potential. This review summarizes the findings on the specific mechanisms and pathways known to modulate the pathogenesis of BoHV-1 and BoHV-5, particularly in relation with respiratory and neurological syndromes, which characterize the infections by each virus, respectively.

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