Rhabdomyolysis in water buffaloes (Bubalus bubalis)
Rhabdomyolysis is a myopathy characterized by severe acute myonecrosis with lysis of muscle cells and extravasation of its content into the bloodstream, causing a secondary renal failure and myoglobinuria. Case-reports have been documented in a wide range of wild or domestic animal species, but t...
| Main Authors: | , , , , , , , |
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| Format: | info:ar-repo/semantics/artículo |
| Language: | Inglés |
| Published: |
Brazilian Association of Veterinary Pathology
2020
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12123/6699 https://bjvp.org.br/banner/2019/11/v-12-n-3-10-rhabdomyolysis-in-water-buffaloes-bubalus-bubalis/ http://dx.doi.org/10.24070/bjvp.1983-0246.v12i3p139-143 |
| Summary: | Rhabdomyolysis is a myopathy characterized by severe acute myonecrosis with lysis of muscle
cells and extravasation of its content into the bloodstream, causing a secondary renal failure
and myoglobinuria. Case-reports have been documented in a wide range of wild or domestic
animal species, but to our knowledge, no reports in water buffaloes (Bubalus bubalis) have
been done. Three animals had signs of paralysis, muscle tremors and myoglobinuria while
others died spontaneously. Samples of blood from affected animals showed increased levels of
creatin kinase (CK), potassium (K), aspartate transaminase (AST), and lactate dehydrogenase
(LDH). In addition, Selenium (Se) levels of those animals were low. Necropsy findings consisted
of severe gelatinous and yellowish edema and pallor of the skeletal muscles of the hind limbs,
lumbar, cervical and scapular region. Microscopically, acute and severe segmental monophasic
coagulative necrosis of skeletal muscles and acute pigmentary tubular nephrosis was observed.
We suspect that selenium deficiency was a predisposing factor of rhabdomyolysis in this
particular case. |
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