Exploring gene networks in two sunflower lines with contrasting leaf senescence phenotype using a system biology approach

Background: Leaf senescence is a complex process, controlled by multiple genetic and environmental variables. In sunflower, leaf senescence is triggered abruptly following anthesis thereby limiting the capacity of plants to keep their green leaf area during grain filling, which subsequently has a st...

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Autores principales: Moschen, Sebastian, Marino, Johanna, Nicosia, Salvador, Higgins, Janet, Alseekh, Saleh, Astigueta, Francisco, Bengoa Luoni, Sofia Ailin, Rivarola, Maximo Lisandro, Fernie, Alisdair R., Blanchet, Nicolas, Langlade, Nicolas B., Paniego, Norma Beatriz, Fernandez, Paula Del Carmen, Heinz, Ruth Amelia
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: BMC 2019
Materias:
Acceso en línea:https://bmcplantbiol.biomedcentral.com/articles/10.1186/s12870-019-2021-6
http://hdl.handle.net/20.500.12123/6248
https://doi.org/10.1186/s12870-019-2021-6
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author Moschen, Sebastian
Marino, Johanna
Nicosia, Salvador
Higgins, Janet
Alseekh, Saleh
Astigueta, Francisco
Bengoa Luoni, Sofia Ailin
Rivarola, Maximo Lisandro
Fernie, Alisdair R.
Blanchet, Nicolas
Langlade, Nicolas B.
Paniego, Norma Beatriz
Fernandez, Paula Del Carmen
Heinz, Ruth Amelia
author_browse Alseekh, Saleh
Astigueta, Francisco
Bengoa Luoni, Sofia Ailin
Blanchet, Nicolas
Fernandez, Paula Del Carmen
Fernie, Alisdair R.
Heinz, Ruth Amelia
Higgins, Janet
Langlade, Nicolas B.
Marino, Johanna
Moschen, Sebastian
Nicosia, Salvador
Paniego, Norma Beatriz
Rivarola, Maximo Lisandro
author_facet Moschen, Sebastian
Marino, Johanna
Nicosia, Salvador
Higgins, Janet
Alseekh, Saleh
Astigueta, Francisco
Bengoa Luoni, Sofia Ailin
Rivarola, Maximo Lisandro
Fernie, Alisdair R.
Blanchet, Nicolas
Langlade, Nicolas B.
Paniego, Norma Beatriz
Fernandez, Paula Del Carmen
Heinz, Ruth Amelia
author_sort Moschen, Sebastian
collection INTA Digital
description Background: Leaf senescence is a complex process, controlled by multiple genetic and environmental variables. In sunflower, leaf senescence is triggered abruptly following anthesis thereby limiting the capacity of plants to keep their green leaf area during grain filling, which subsequently has a strong impact on crop yield. Recently, we performed a selection of contrasting sunflower inbred lines for the progress of leaf senescence through a physiological, cytological and molecular approach. Here we present a large scale transcriptomic analysis using RNA-seq and its integration with metabolic profiles for two contrasting sunflower inbred lines, R453 and B481–6 (early and delayed senescence respectively), with the aim of identifying metabolic pathways associated to leaf senescence. Results: Gene expression profiles revealed a higher number of differentially expressed genes, as well as, higher expression levels in R453, providing evidence for early activation of the senescence program in this line. Metabolic pathways associated with sugars and nutrient recycling were differentially regulated between the lines. Additionally, we identified transcription factors acting as hubs in the co-expression networks; some previously reported as senescence-associated genes in model species but many are novel candidate genes. Conclusions: Understanding the onset and the progress of the senescence process in crops and the identification of these new candidate genes will likely prove highly useful for different management strategies to mitigate the impact of senescence on crop yield. Functional characterization of candidate genes will help to develop molecular tools for biotechnological applications in breeding crop yield.
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
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spelling INTA62482019-10-31T11:46:29Z Exploring gene networks in two sunflower lines with contrasting leaf senescence phenotype using a system biology approach Moschen, Sebastian Marino, Johanna Nicosia, Salvador Higgins, Janet Alseekh, Saleh Astigueta, Francisco Bengoa Luoni, Sofia Ailin Rivarola, Maximo Lisandro Fernie, Alisdair R. Blanchet, Nicolas Langlade, Nicolas B. Paniego, Norma Beatriz Fernandez, Paula Del Carmen Heinz, Ruth Amelia Biotecnología Helianthus Annuus Fenotipos Avejentamiento Hojas Genética Biotechnology Phenotypes Senescence Leaves Genetics Girasol Sunflower Background: Leaf senescence is a complex process, controlled by multiple genetic and environmental variables. In sunflower, leaf senescence is triggered abruptly following anthesis thereby limiting the capacity of plants to keep their green leaf area during grain filling, which subsequently has a strong impact on crop yield. Recently, we performed a selection of contrasting sunflower inbred lines for the progress of leaf senescence through a physiological, cytological and molecular approach. Here we present a large scale transcriptomic analysis using RNA-seq and its integration with metabolic profiles for two contrasting sunflower inbred lines, R453 and B481–6 (early and delayed senescence respectively), with the aim of identifying metabolic pathways associated to leaf senescence. Results: Gene expression profiles revealed a higher number of differentially expressed genes, as well as, higher expression levels in R453, providing evidence for early activation of the senescence program in this line. Metabolic pathways associated with sugars and nutrient recycling were differentially regulated between the lines. Additionally, we identified transcription factors acting as hubs in the co-expression networks; some previously reported as senescence-associated genes in model species but many are novel candidate genes. Conclusions: Understanding the onset and the progress of the senescence process in crops and the identification of these new candidate genes will likely prove highly useful for different management strategies to mitigate the impact of senescence on crop yield. Functional characterization of candidate genes will help to develop molecular tools for biotechnological applications in breeding crop yield. EEA Famaillá Fil: Moschen, Sebastian Nicolás. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Famaillá; Argentina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Marino, Johanna. Universidad Nacional de San Martín. Escuela de Ciencia y Tecnología; Argentina Fil: Nicosia, Salvador. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Higgins, Janet. Norwich Research Park. Earlham Institute; Reino Unido Fil: Alseekh, Saleh. Max-Planck-Institut für Molekulare Pflanzenphysiologie; Alemania Fil: Astigueta, Francisco. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Bengoa Luoni, Sofia Ailin. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto Tecnológico Chascomús. Universidad Nacional de General San Martín. Instituto Tecnológico Chascomús; Argentina Fil: Rivarola, Maximo Lisandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Fernie, Alisdair R. Max-Planck-Institut für Molekulare Pflanzenphysiologie; Alemania Fil: Blanchet, Nicolas. Université de Toulouse. LIPM-INRA-CNRS; Francia Fil: Langlade, Nicolas B. Université de Toulouse. LIPM-INRA-CNRS; Francia Fil: Paniego, Norma Beatriz. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Fernandez, Paula Del Carmen. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Heinz, Ruth Amelia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Agrobiotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina 2019-10-31T11:44:37Z 2019-10-31T11:44:37Z 2019-10 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://bmcplantbiol.biomedcentral.com/articles/10.1186/s12870-019-2021-6 http://hdl.handle.net/20.500.12123/6248 1471-2229 https://doi.org/10.1186/s12870-019-2021-6 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf BMC BMC Plant Biology 19 : Article number 446 (October 2019)
spellingShingle Biotecnología
Helianthus Annuus
Fenotipos
Avejentamiento
Hojas
Genética
Biotechnology
Phenotypes
Senescence
Leaves
Genetics
Girasol
Sunflower
Moschen, Sebastian
Marino, Johanna
Nicosia, Salvador
Higgins, Janet
Alseekh, Saleh
Astigueta, Francisco
Bengoa Luoni, Sofia Ailin
Rivarola, Maximo Lisandro
Fernie, Alisdair R.
Blanchet, Nicolas
Langlade, Nicolas B.
Paniego, Norma Beatriz
Fernandez, Paula Del Carmen
Heinz, Ruth Amelia
Exploring gene networks in two sunflower lines with contrasting leaf senescence phenotype using a system biology approach
title Exploring gene networks in two sunflower lines with contrasting leaf senescence phenotype using a system biology approach
title_full Exploring gene networks in two sunflower lines with contrasting leaf senescence phenotype using a system biology approach
title_fullStr Exploring gene networks in two sunflower lines with contrasting leaf senescence phenotype using a system biology approach
title_full_unstemmed Exploring gene networks in two sunflower lines with contrasting leaf senescence phenotype using a system biology approach
title_short Exploring gene networks in two sunflower lines with contrasting leaf senescence phenotype using a system biology approach
title_sort exploring gene networks in two sunflower lines with contrasting leaf senescence phenotype using a system biology approach
topic Biotecnología
Helianthus Annuus
Fenotipos
Avejentamiento
Hojas
Genética
Biotechnology
Phenotypes
Senescence
Leaves
Genetics
Girasol
Sunflower
url https://bmcplantbiol.biomedcentral.com/articles/10.1186/s12870-019-2021-6
http://hdl.handle.net/20.500.12123/6248
https://doi.org/10.1186/s12870-019-2021-6
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