Systemic administration of imiquimod as an adjuvant improves immunogenicity of a tumor-lysate vaccine inducing the rejection of a highly aggressive T-cell lymphoma

T-cell lymphomas include diverse malignancies. They are rare, some have low survival rates and they lack curative therapies. The aim of this work was to assess whether employing the TLR7 agonist imiquimod and the T-cell costimulatory molecule CD40 or the combination of both as adjuvants of a cell ly...

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Bibliographic Details
Main Authors: Di Sciullo, Maria Paula, Menay, Florencia, Cocozza, Federico, Gravisaco, María José, Waldner, Claudia Inés, Mongini, Claudia
Format: info:ar-repo/semantics/artículo
Language:Inglés
Published: Elsevier 2019
Subjects:
Online Access:https://www.sciencedirect.com/science/article/pii/S1521661618304212
http://hdl.handle.net/20.500.12123/6229
https://doi.org/10.1016/j.clim.2019.04.013

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