Characterization of CD79acy + cells in placentas from ruminants
Previous work carried out to characterise different immune cells in ruminant placentas found strong CD79αcynuclear labelling in cells histologically resembling trophoblast cells. In the attempt to characterize this cellpopulation, placentomes collected from cattle, sheep and water buffaloes...
| Main Authors: | , , , , |
|---|---|
| Format: | info:ar-repo/semantics/artículo |
| Language: | Inglés |
| Published: |
Elsevier
2019
|
| Subjects: | |
| Online Access: | https://www.sciencedirect.com/science/article/pii/S0165242719301849 http://hdl.handle.net/20.500.12123/6201 https://doi.org/10.1016/j.vetimm.2019.109942 |
| _version_ | 1855035633405263872 |
|---|---|
| author | Canton, German Jose Schock, Alex Melo de Sousa, Noelita Beckers, Jean-Francois Chianini, Francesca |
| author_browse | Beckers, Jean-Francois Canton, German Jose Chianini, Francesca Melo de Sousa, Noelita Schock, Alex |
| author_facet | Canton, German Jose Schock, Alex Melo de Sousa, Noelita Beckers, Jean-Francois Chianini, Francesca |
| author_sort | Canton, German Jose |
| collection | INTA Digital |
| description | Previous work carried out to characterise different immune cells in ruminant placentas found strong CD79αcynuclear labelling in cells histologically resembling trophoblast cells. In the attempt to characterize this cellpopulation, placentomes collected from cattle, sheep and water buffaloes were examined by im-munohistochemistry with single and double labelling using monoclonal antibodies (mAb) against B lymphocytesand trophoblast cells. Most CD79αcy+ cells co-expressed placental lactogen or cytokeratin and were CD21 andMHC class II negative strongly suggesting they do not have a B cell origin. However, a potential immunologicalrole of these cells cannot be ruled out and it is currently unknown if thefindings des |
| format | info:ar-repo/semantics/artículo |
| id | INTA6201 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | INTA62012019-10-24T18:54:10Z Characterization of CD79acy + cells in placentas from ruminants Canton, German Jose Schock, Alex Melo de Sousa, Noelita Beckers, Jean-Francois Chianini, Francesca Respuesta Inmunológica Placenta Rumiante Anticuerpos Embriones Animales Immune Response Ruminants Antibodies Animal Embryos Previous work carried out to characterise different immune cells in ruminant placentas found strong CD79αcynuclear labelling in cells histologically resembling trophoblast cells. In the attempt to characterize this cellpopulation, placentomes collected from cattle, sheep and water buffaloes were examined by im-munohistochemistry with single and double labelling using monoclonal antibodies (mAb) against B lymphocytesand trophoblast cells. Most CD79αcy+ cells co-expressed placental lactogen or cytokeratin and were CD21 andMHC class II negative strongly suggesting they do not have a B cell origin. However, a potential immunologicalrole of these cells cannot be ruled out and it is currently unknown if thefindings des EEA Balcarce Fil: Cantón, Germán José. Pentlands Science Park. Moredun Research Institute; Gran Bretaña. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Schock, Alex. Pentlands Science Park. Animal and Plant Health Agency (APHA) Lasswade; Gran Bretaña Fil: Melo de Sousa, Noelita. University of Liège. Faculty of Veterinary Medicine. Physiology of Reproduction; Bélgica Fil: Beckers, Jeans Francois. University of Liège. Faculty of Veterinary Medicine. Physiology of Reproduction; Bélgica Fil: Chianini, Francesca. Pentlands Science Park. Moredun Research Institute; Gran Bretaña 2019-10-24T18:42:15Z 2019-10-24T18:42:15Z 2019-11 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://www.sciencedirect.com/science/article/pii/S0165242719301849 http://hdl.handle.net/20.500.12123/6201 0165-2427 https://doi.org/10.1016/j.vetimm.2019.109942 eng info:eu-repo/semantics/restrictedAccess application/pdf Elsevier Veterinary immunology and immunopathology 217 : 109942. (November 2019) |
| spellingShingle | Respuesta Inmunológica Placenta Rumiante Anticuerpos Embriones Animales Immune Response Ruminants Antibodies Animal Embryos Canton, German Jose Schock, Alex Melo de Sousa, Noelita Beckers, Jean-Francois Chianini, Francesca Characterization of CD79acy + cells in placentas from ruminants |
| title | Characterization of CD79acy + cells in placentas from ruminants |
| title_full | Characterization of CD79acy + cells in placentas from ruminants |
| title_fullStr | Characterization of CD79acy + cells in placentas from ruminants |
| title_full_unstemmed | Characterization of CD79acy + cells in placentas from ruminants |
| title_short | Characterization of CD79acy + cells in placentas from ruminants |
| title_sort | characterization of cd79acy cells in placentas from ruminants |
| topic | Respuesta Inmunológica Placenta Rumiante Anticuerpos Embriones Animales Immune Response Ruminants Antibodies Animal Embryos |
| url | https://www.sciencedirect.com/science/article/pii/S0165242719301849 http://hdl.handle.net/20.500.12123/6201 https://doi.org/10.1016/j.vetimm.2019.109942 |
| work_keys_str_mv | AT cantongermanjose characterizationofcd79acycellsinplacentasfromruminants AT schockalex characterizationofcd79acycellsinplacentasfromruminants AT melodesousanoelita characterizationofcd79acycellsinplacentasfromruminants AT beckersjeanfrancois characterizationofcd79acycellsinplacentasfromruminants AT chianinifrancesca characterizationofcd79acycellsinplacentasfromruminants |