Pathology of cattle experimentally intoxicated with ground Ricinus communis seeds
Five Aberdeen Angus calves were inoculated intra-ruminally with ground seeds of Ricinus communis at doses of 1, 1.5, 2 or 3 gr per kg of body weight, or with saline solution (control), respectively. Grossly, all intoxicated animals showed hemorrhages in abdominal serosas, epicardium, endocardium, sp...
| Main Authors: | , , , , , , |
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| Format: | Artículo |
| Language: | Inglés |
| Published: |
Brazilian Association of Veterinary Pathology
2019
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12123/5667 https://bjvp.org.br/bjvp-archive/2018/11/vol-11-n-3-november-2018/ http://dx.doi.org/10.24070/bjvp.1983-0246.v11i3p86-91 |
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| author | Marin, Raul Eduardo Schild, Carlos Garcia, Juan Canton, German Jose Micheloud, Juan Francisco Morrell, Eleonora Lidia Uzal, Francisco Aleja |
| author_browse | Canton, German Jose Garcia, Juan Marin, Raul Eduardo Micheloud, Juan Francisco Morrell, Eleonora Lidia Schild, Carlos Uzal, Francisco Aleja |
| author_facet | Marin, Raul Eduardo Schild, Carlos Garcia, Juan Canton, German Jose Micheloud, Juan Francisco Morrell, Eleonora Lidia Uzal, Francisco Aleja |
| author_sort | Marin, Raul Eduardo |
| collection | INTA Digital |
| description | Five Aberdeen Angus calves were inoculated intra-ruminally with ground seeds of Ricinus communis at doses of 1, 1.5, 2 or 3 gr per kg of body weight, or with saline solution (control), respectively. Grossly, all intoxicated animals showed hemorrhages in abdominal serosas, epicardium, endocardium, spleen, pre-stomachs, abomasum, and small and large intestine, and diffuse edema of the ruminal mucosa. Microscopically, in all animals inoculated with R. communis seeds, the main feature was the presence of pyknotic and karyorrhectic nuclei in the endothelium of central nervous system, hepatic, ruminal, intestinal, glomerular and alveolar capillaries, and in lymphoid cells of multiple organs. Apoptosis, confirmed by activated caspase-3 immunohistochemistry, was observed in these cells. No gross or microscopic lesions were observed in the control animal. The results of this study suggest that apoptosis is the main mechanism of cell death in cattle intoxicated with R. communis seeds. |
| format | Artículo |
| id | INTA5667 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | Brazilian Association of Veterinary Pathology |
| publisherStr | Brazilian Association of Veterinary Pathology |
| record_format | dspace |
| spelling | INTA56672022-06-03T13:18:47Z Pathology of cattle experimentally intoxicated with ground Ricinus communis seeds Marin, Raul Eduardo Schild, Carlos Garcia, Juan Canton, German Jose Micheloud, Juan Francisco Morrell, Eleonora Lidia Uzal, Francisco Aleja Apoptosis Ganado Bovino Experimentación Ricinus Communis Cattle Experimentation Poisoning Envenenamiento Intoxicación Ricino Five Aberdeen Angus calves were inoculated intra-ruminally with ground seeds of Ricinus communis at doses of 1, 1.5, 2 or 3 gr per kg of body weight, or with saline solution (control), respectively. Grossly, all intoxicated animals showed hemorrhages in abdominal serosas, epicardium, endocardium, spleen, pre-stomachs, abomasum, and small and large intestine, and diffuse edema of the ruminal mucosa. Microscopically, in all animals inoculated with R. communis seeds, the main feature was the presence of pyknotic and karyorrhectic nuclei in the endothelium of central nervous system, hepatic, ruminal, intestinal, glomerular and alveolar capillaries, and in lymphoid cells of multiple organs. Apoptosis, confirmed by activated caspase-3 immunohistochemistry, was observed in these cells. No gross or microscopic lesions were observed in the control animal. The results of this study suggest that apoptosis is the main mechanism of cell death in cattle intoxicated with R. communis seeds. EEA Balcarce Fil: Marin, Raúl. Universidad Nacional de Jujuy; Argentina. Fil: Schild, Carlos. Instituto Nacional de Investigación Agropecuaria (INIA); Uruguay. Fil: García, Juan. Universidad de la República. Centro Universitario de la Región del Este; Uruguay. Fil: Cantón, Germán. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Micheloud, Juan. INTA, Estación Experimental Agropecuaria Salta; Argentina. Fil: Morrell, Eleonora. INTA, Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Uzal, Francisco. Universidad de California; Estados Unidos. 2019-08-22T13:09:06Z 2019-08-22T13:09:06Z 2018-11 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/5667 https://bjvp.org.br/bjvp-archive/2018/11/vol-11-n-3-november-2018/ 1983-0246 http://dx.doi.org/10.24070/bjvp.1983-0246.v11i3p86-91 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Brazilian Association of Veterinary Pathology Brazilian Journal of Veterinary Pathology 11 (3) : 86-91 (November 2018) |
| spellingShingle | Apoptosis Ganado Bovino Experimentación Ricinus Communis Cattle Experimentation Poisoning Envenenamiento Intoxicación Ricino Marin, Raul Eduardo Schild, Carlos Garcia, Juan Canton, German Jose Micheloud, Juan Francisco Morrell, Eleonora Lidia Uzal, Francisco Aleja Pathology of cattle experimentally intoxicated with ground Ricinus communis seeds |
| title | Pathology of cattle experimentally intoxicated with ground Ricinus communis seeds |
| title_full | Pathology of cattle experimentally intoxicated with ground Ricinus communis seeds |
| title_fullStr | Pathology of cattle experimentally intoxicated with ground Ricinus communis seeds |
| title_full_unstemmed | Pathology of cattle experimentally intoxicated with ground Ricinus communis seeds |
| title_short | Pathology of cattle experimentally intoxicated with ground Ricinus communis seeds |
| title_sort | pathology of cattle experimentally intoxicated with ground ricinus communis seeds |
| topic | Apoptosis Ganado Bovino Experimentación Ricinus Communis Cattle Experimentation Poisoning Envenenamiento Intoxicación Ricino |
| url | http://hdl.handle.net/20.500.12123/5667 https://bjvp.org.br/bjvp-archive/2018/11/vol-11-n-3-november-2018/ http://dx.doi.org/10.24070/bjvp.1983-0246.v11i3p86-91 |
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